Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Brian E Fee"'
Autor:
Prashant Rai, Martin Sharpe, Charan K. Ganta, Paul J. Baker, Katrin D. Mayer-Barber, Brian E. Fee, Gregory A. Taylor, Michael B. Fessler
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Externí odkaz:
https://doaj.org/article/6ca47ef1b2184a5eb91872baf4a58d7d
Autor:
Yazan Alwarawrah, Keiko Danzaki, Amanda G. Nichols, Brian E. Fee, Cheryl Bock, Gary Kucera, Laura P. Hale, Gregory A. Taylor, Nancie J. MacIver
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Immunity Related GTPases (IRG) are a family of proteins produced during infection that regulate membrane remodeling events in cells, particularly autophagy and mitophagy. The human IRGM gene has been strongly associated with Crohn’s diseas
Externí odkaz:
https://doaj.org/article/9e50381ee66e446780fb21acef46e994
Autor:
Aparna C. Swaminathan, Hongmei Zhu, Victor Tapson, Yuliya Lokhnygina, Abby Poms, Zach Kelleher, Elijah Gaspard, Karla Kennedy, Brian E. Fee, Terry Fortin, S. Nicholas Mason, Kishan Parikh, Tim J. McMahon
Publikováno v:
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Multiple classes of oral therapy are available for the treatment of pulmonary arterial hypertension (PAH), but there is little to guide clinicians in choosing a specific regimen or therapeutic class. We aimed to investigate whethe
Externí odkaz:
https://doaj.org/article/92fe33bd0f0a4461aeb63464bf07a18e
Autor:
Hsin-I. Huang, Mark L. Jewell, Nourhan Youssef, Min-Nung Huang, Elizabeth R. Hauser, Brian E. Fee, Nathan P. Rudemiller, Jamie R. Privratsky, Junyi J. Zhang, Estefany Y. Reyes, Donghai Wang, Gregory A. Taylor, Michael D. Gunn, Dennis C. Ko, Donald N. Cook, Vidyalakshmi Chandramohan, Steven D. Crowley, Gianna Elena Hammer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Intestinal immunity is coordinated by specialized mononuclear phagocyte populations, constituted by a diversity of cell subsets. Although the cell subsets constituting the mononuclear phagocyte network are thought to be similar in both small and larg
Externí odkaz:
https://doaj.org/article/ec895c03dad444b39ecd52aa071d83d9
Autor:
Gregory A Taylor, Hsin-I Huang, Brian E Fee, Nourhan Youssef, Mark L Jewell, Viviana Cantillana, Alexi A Schoenborn, Allison R Rogala, Anne F Buckley, Carl G Feng, Bruce A Vallance, Ajay S Gulati, Gianna E Hammer
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008553 (2020)
IRGM and its mouse orthologue Irgm1 are dynamin-like proteins that regulate vesicular remodeling, intracellular microbial killing, and pathogen immunity. IRGM dysfunction is linked to inflammatory bowel disease (IBD), and while it is thought that def
Externí odkaz:
https://doaj.org/article/0f551c4084a24ce09013efa7ff036e98
Autor:
Allison R. Rogala, Alexi A. Schoenborn, Brian E. Fee, Viviana A. Cantillana, Maria J. Joyce, Raad Z. Gharaibeh, Sayanty Roy, Anthony A. Fodor, R. Balfour Sartor, Gregory A. Taylor, Ajay S. Gulati
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 2 (2018)
Crohn's disease (CD) represents a chronic inflammatory disorder of the intestinal tract. Several susceptibility genes have been linked to CD, though their precise role in the pathogenesis of this disorder remains unclear. Immunity-related GTPase M (I
Externí odkaz:
https://doaj.org/article/2015fd711c414025973890eb9e992121
Publikováno v:
Infect Immun
Gamma-interferon (IFNγ)-induced immunity-related GTPases (IRGs) confer cell-autonomous immunity to the intracellular protozoan pathogen Toxoplasma gondii. Effector IRGs are loaded onto the Toxoplasma-containing parasitophorous vacuole (PV), where th
Autor:
Nourhan Youssef, Donald N. Cook, Gianna E. Hammer, Vidyalakshmi Chandramohan, Elizabeth R. Hauser, Gregory A. Taylor, Dennis C. Ko, Junyi J. Zhang, Steven D. Crowley, Hsin-I Huang, Nathan P. Rudemiller, Min-Nung Huang, Estefany Y. Reyes, Jamie R. Privratsky, Michael D. Gunn, Brian E. Fee, Donghai Wang, Mark L. Jewell
Intestinal immunity is coordinated by specialized mononuclear phagocyte populations, constituted by a diversity of cell subsets. Although the cell subsets constituting the mononuclear phagocyte network are thought to be similar in both small and larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee4710a452201e2367b49fd89c7ba61
https://doi.org/10.1101/2021.01.28.428597
https://doi.org/10.1101/2021.01.28.428597
Autor:
Timothy J. McMahon, Terry Fortin, S. Nicholas Mason, Abby Poms, Elijah Gaspard, Hongmei Zhu, Yuliya Lokhnygina, Brian E. Fee, Karla Kennedy, Victor F. Tapson, Zach Kelleher, Kishan S. Parikh, Aparna Swaminathan
Publikováno v:
Respiratory Research
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Respiratory Research, Vol 21, Iss 1, Pp 1-11 (2020)
Background Multiple classes of oral therapy are available for the treatment of pulmonary arterial hypertension (PAH), but there is little to guide clinicians in choosing a specific regimen or therapeutic class. We aimed to investigate whether treatme
Autor:
Hsin-I Huang, Viviana Cantillana, Ajay S. Gulati, Gregory A. Taylor, Gianna E. Hammer, Mark L. Jewell, Allison R. Rogala, Anne F. Buckley, Nourhan Youssef, Alexi A. Schoenborn, Bruce A. Vallance, Carl G. Feng, Brian E. Fee
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 5, p e1008553 (2020)
PLoS Pathogens, Vol 16, Iss 5, p e1008553 (2020)
IRGM and its mouse orthologue Irgm1 are dynamin-like proteins that regulate vesicular remodeling, intracellular microbial killing, and pathogen immunity. IRGM dysfunction is linked to inflammatory bowel disease (IBD), and while it is thought that def