Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Brian E, O'Neill"'
Publikováno v:
Vaccines, Vol 2, Iss 2, Pp 216-227 (2014)
Modulation of the cytokine milieu is one approach for vaccine development. However, therapy with pro-inflammatory cytokines, such as IL-12, is limited in practice due to adverse systemic effects. Spatially-restricted gene expression circumvents this
Externí odkaz:
https://doaj.org/article/7ec86175d4894baaadddf69c93233baa
Publikováno v:
Molecular Imaging
Heat shock protein expression can be induced by heat shock making it possible to artificially modulate their levels noninvasively in vivo in a spatially and temporally controlled manner. Here, we report the use of the major heat shock protein 70 (HSP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e02539863769ebdedc844026cc138541
https://pubmed.ncbi.nlm.nih.gov/33216684
https://pubmed.ncbi.nlm.nih.gov/33216684
Publikováno v:
Journal of Controlled Release. 258:67-72
The cell membrane is a semi-fluid container that defines the boundary of cells, and provides an enclosed environment for vital biological processes. A sound excitable drug (SED) that is non-cytotoxic to cells is developed to disrupt the plasma membra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a0aac12ec29636b9479efbc66ec91d
https://doi.org/10.1016/j.jconrel.2017.05.009
https://doi.org/10.1016/j.jconrel.2017.05.009
Publikováno v:
Journal of Controlled Release. 206:153-160
Intravital imaging of nanoparticle extravasation and tumor accumulation has revealed, for the first time, detailed features of carrier and drug behavior in circulation and tissue that suggest new directions for optimization of drug nanocarriers. Usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6788f17903c3e862188d00218439f5ba
https://doi.org/10.1016/j.jconrel.2015.03.010
https://doi.org/10.1016/j.jconrel.2015.03.010
Autor:
Chandni Valson, Nahuel Fittipaldi, Brian E. O'Neill, Randall J. Olsen, Anthony R. Flores, Priyanka Kachroo, Jeff R. Anderson, Christof Karmonik, Misu A. Sanson, Concepcion C. Cantu, James M. Musser, Muthiah Kumaraswami, Nishanth Makthal
Publikováno v:
American Journal of Pathology
Single-nucleotide polymorphisms (SNPs) are the most common source of genetic variation within a species; however, few investigations demonstrate how naturally occurring SNPs may increase strain virulence. We recently used group A Streptococcus as a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::589913dd2ad57d93728563e24c8d7e95
Autor:
Elisabetta Sassaroli, Brian E. O'Neill
Publikováno v:
Physics in Medicine and Biology. 59:6775-6795
High intensity focused ultrasound (HIFU) operated in thermal mode has been reported to reduce interstitial fluid pressure and improve the penetration of large macromolecules and nanoparticles in tumor and normal tissue. Little is understood about how
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c297c53f818dfd98242deef9646527
https://doi.org/10.1088/0031-9155/59/22/6775
https://doi.org/10.1088/0031-9155/59/22/6775
Autor:
Xuewu Liu, Brian E. O'Neill, Mauro Ferrari, Anna Lisa Palange, Jaehong Key, F. Tatulli, Paolo Decuzzi, Yoo Shin Kim, Maricela R. Ramirez, Santosh Aryal, Reginald F. Munden
Publikováno v:
Clinical and Translational Imaging. 2:427-437
Malignancies of the lungs, both primary and metastatic, are the leading cause of death worldwide. Over 1.5 million new cases of primary lung cancer are diagnosed annually worldwide with a dismal five-year survival rate of approximately 15%, which rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9e671a632949b65cdaf2ed4c04e47c
https://doi.org/10.1007/s40336-014-0078-7
https://doi.org/10.1007/s40336-014-0078-7
Publikováno v:
Open Journal of Radiology. :329-338
Objectives: To demonstrate in vitro that changes in ultrasound cavitation threshold might be used for non-invasively distinguishing high viscosity mucinous fluid from low viscosity serous fluid in cystic masses, based on the facts that cavitation thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57f9b22e93261d76b16563278eaedbf0
https://doi.org/10.4236/ojrad.2014.44043
https://doi.org/10.4236/ojrad.2014.44043
Publikováno v:
Bioconjugate Chemistry. 24:1937-1944
Tumor angiogenesis is an important component of cancer biology driven in part by the hypothesis that tumor vessel growth is a necessary requirement for tumor growth. Angiogenesis does not only depend on endothelial cell invasion and proliferation, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::451acc85fcf8854f21b332b6975662d1
https://doi.org/10.1021/bc400374t
https://doi.org/10.1021/bc400374t
Publikováno v:
Journal of Liposome Research. 23:197-202
Liposomes have a long history as passive and active drug carriers. Recently, a few methods have been realized to control the release from liposomes, including heating, ultrasound and laser.We report on a new approach to drive release from liposomes u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d0874ceea457c7dce2b6040366e307
https://doi.org/10.3109/08982104.2013.788024
https://doi.org/10.3109/08982104.2013.788024