Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Brian E, Caffrey"'
Autor:
Stefanie M. Herbel, Lambert Moyon, Marvin Christ, Eslam M. Elsayed, Brian E. Caffrey, Silke Malmsheimer, Iwan Grin, Kerstin Hoffmann, Kristin Surmann, Sascha Blankenburg, Anna Lena Jung, Christina E. Herkt, Marco Borsò, Beyza Bozdag, Axel Imhof, Anke Becker, Samuel Wagner, Gert Bange, Uwe Völker, Wilhelm Bertrams, Annalisa Marsico, Bernd Schmeck
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 2042-2058 (2022)
Legionella pneumophila (L.p.) is a bacterial pathogen which is a common causative agent of pneumonia. In humans, it infects alveolar macrophages and transfers hundreds of virulence factors that interfere with cellular signalling pathways and the tran
Externí odkaz:
https://doaj.org/article/3cfbe5db3b0f4145a005db5fed54388b
Autor:
Christina E. Herkt, Brian E. Caffrey, Kristin Surmann, Sascha Blankenburg, Manuela Gesell Salazar, Anna L. Jung, Stefanie M. Herbel, Kerstin Hoffmann, Leon N. Schulte, Wei Chen, Alexandra Sittka-Stark, Uwe Völker, Martin Vingron, Annalisa Marsico, Wilhelm Bertrams, Bernd Schmeck
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Legionella pneumophila is an important cause of pneumonia. It invades alveolar macrophages and manipulates the immune response by interfering with signaling pathways and gene transcription to support its own replication. MicroRNAs (miRNAs) a
Externí odkaz:
https://doaj.org/article/f562f453df8b4591a2a3cac252c1f3ca
Autor:
Brian E. Caffrey, Falko Apel, Robert Streeck, Arthur I. Skoultchi, Gabriel Sollberger, Arturo Zychlinsky
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Neutrophils are important innate immune cells that tackle invading pathogens with different effector mechanisms. They acquire this antimicrobial potential during their maturation in the bone marrow, where they differentiate from hematopoietic stem ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba8246a54ed234f174838ae6653500d
https://hdl.handle.net/21.11116/0000-0006-8A94-721.11116/0000-0006-8A96-5
https://hdl.handle.net/21.11116/0000-0006-8A94-721.11116/0000-0006-8A96-5
Autor:
Brian E. Caffrey, C Herkt, Leon N. Schulte, Annalisa Marsico, Bernd Schmeck, Kerstin Hoffmann, Wei Chen, Uwe Völker, Wilhelm Bertrams, Stefanie M. Herbel, Sascha Blankenburg, Alexandra Sittka-Stark, Manuela Gesell Salazar, Kristin Surmann, Anna L. Jung, Martin Vingron
Publikováno v:
mBio 11:e03155-19 (2020)
mBio, Vol 11, Iss 2 (2020)
mBio
mBio, Vol 11, Iss 2, p e03155-19 (2020)
mBio, Vol 11, Iss 2 (2020)
mBio
mBio, Vol 11, Iss 2, p e03155-19 (2020)
Cases of Legionella pneumophila pneumonia occur worldwide, with potentially fatal outcome. When causing human disease, Legionella injects a plethora of virulence factors to reprogram macrophages to circumvent immune defense and create a replication n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2825320d9f4e2e9532f64b122681c0a
https://doi.org/10.1128/mbio.03155-19
https://doi.org/10.1128/mbio.03155-19
Autor:
Brian E Caffrey, Tom A Williams, Xiaowei Jiang, Christina Toft, Karsten Hokamp, Mario A Fares
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35659 (2012)
Functional divergence is the process by which new genes and functions originate through the modification of existing ones. Both genetic and environmental factors influence the evolution of new functions, including gene duplication or changes in the e
Externí odkaz:
https://doaj.org/article/df3d863eabe04e30bc4bbe9925194b8a
Neutrophils are important innate immune cells that tackle invading pathogens with different effector mechanisms. They acquire this antimicrobial potential during their maturation in the bone marrow, where they differentiate from hematopoietic stem ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f7780836ef92cc9e9280d304fa8b22
https://doi.org/10.1101/763482
https://doi.org/10.1101/763482
Autor:
Sandrine Hughes, Jumamurat R. Bayjanov, Maria Elena Martino, Benjamin Gillet, Sacha A. F. T. van Hijum, Michiel Wels, Michiel Kleerebezem, Brian E. Caffrey, Pauline Joncour, François Leulier
Publikováno v:
Environmental Microbiology. 18:4974-4989
The ability of bacteria to adapt to diverse environmental conditions is well-known. The process of bacterial adaptation to a niche has been linked to large changes in the genome content, showing that many bacterial genomes reflect the constraints imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5978edd8ecdfae0db186f16592d4e7ac
https://doi.org/10.1111/1462-2920.13455
https://doi.org/10.1111/1462-2920.13455
Autor:
Victor F, Oliveira, Lauro A G, Moares, Ester A, Mota, Liana K, Jannotti-Passos, Paulo M Z, Coelho, Ana C A, Mattos, Flávia F B, Couto, Brian E, Caffrey, Annalisa, Marsico, Renata, Guerra-Sá
Publikováno v:
BioMed Research International
Long noncoding RNAs (lncRNAs) are transcripts generally longer than 200 nucleotides with no or poor protein coding potential, and most of their functions are also poorly characterized. Recently, an increasing number of studies have shown that lncRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::08bef69d68e7a454e6ef96eeafb63e7d
https://pubmed.ncbi.nlm.nih.gov/30112357
https://pubmed.ncbi.nlm.nih.gov/30112357
Autor:
Ana Carolina Alves de Mattos, Flavia Fernanda Bubula Couto, Paulo Marcos Zech Coelho, Renata Guerra-Sá, Ester Alves Mota, Liana K. Jannotti-Passos, Annalisa Marsico, Brian E. Caffrey, Lauro A. G. Moares, Victor F. Oliveira
Publikováno v:
BioMed Research International, Vol 2018 (2018)
Long noncoding RNAs (lncRNAs) are transcripts generally longer than 200 nucleotides with no or poor protein coding potential, and most of their functions are also poorly characterized. Recently, an increasing number of studies have shown that lncRNAs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1299e6433bee755967099a137a87c3a3