Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Brian D. Scherzer"'
Autor:
Toyzan Todd William, James M. Renga, Mcconnell James R, Gary Roth, Douglas C. Bland, Martin Timothy P, Ronald Ross, Podhorez David E, Stacey L. Powers, Nicholas M. Irvine, Brian D. Scherzer, Kim E. Arndt
Publikováno v:
Organic Process Research & Development. 19:454-462
A scalable process to the insecticide Isoclast manufactured by Dow AgroSciences LLC is described. The process involves the de novo construction of a fully elaborated pyridine sulfide using enamine-mediated cyclization followed by two efficient and in
Autor:
James E. Hitt, Shakil A. Saghir, Brian D. Scherzer, Dan A. Markham, Gary B. Kupperblatt, Jonathan C. Evans, Edmund J. Elder
Publikováno v:
Drug Development and Industrial Pharmacy. 33:755-765
Many new molecular entities targeted for pharmaceutical applications face serious development challenges because of poor water solubility. Although particle engineering technologies such as controlled precipitation have been shown to enhance aqueous
Autor:
Keith P. Johnston, Josh D. Engstrom, Kirk Overhoff, Brian D. Scherzer, Thomas E. Milner, Robert O. Williams, Bo Chen
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 65(1)
An ultra-rapid freezing (URF) technology has been developed to produce high surface area powders composed of solid solutions of an active pharmaceutical ingredient (API) and a polymer stabilizer. A solution of API and polymer excipient(s) is spread o