Zobrazeno 1 - 10
of 552
pro vyhledávání: '"Brian D Ross"'
Publikováno v:
Substance Abuse: Research and Treatment, Vol 2010, Iss 4, Pp 9-20 (2010)
Introduction: Chronic methamphetamine use results in persistent neuropsychological deficits in abstinent methamphetamine dependent (AMD) subjects. We examined the hypothesis that elevated concentration of cerebral glutamate (Glu), an excitatory neuro
Externí odkaz:
https://doaj.org/article/dd4806e1b9e240179ef34e56dca31029
Autor:
Craig J Galbán, Bing Ma, Dariya Malyarenko, Martin D Pickles, Kevin Heist, Norah L Henry, Anne F Schott, Colleen H Neal, Nola M Hylton, Alnawaz Rehemtulla, Timothy D Johnson, Charles R Meyer, Thomas L Chenevert, Lindsay W Turnbull, Brian D Ross
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122151 (2015)
PurposeTo evaluate diffusion weighted MRI (DW-MR) as a response metric for assessment of neoadjuvant chemotherapy (NAC) in patients with primary breast cancer using prospective multi-center trials which provided MR scans along with clinical outcome i
Externí odkaz:
https://doaj.org/article/f38230b542824a37b5543fad65f16c3f
Autor:
Jean-Christophe Brisset, Benjamin A Hoff, Thomas L Chenevert, Jon A Jacobson, Jennifer L Boes, Stefanie Galbán, Alnawaz Rehemtulla, Timothy D Johnson, Kenneth J Pienta, Craig J Galbán, Charles R Meyer, Timothy Schakel, Klaas Nicolay, Ajjai S Alva, Maha Hussain, Brian D Ross
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123877 (2015)
Bone metastasis occurs for men with advanced prostate cancer which promotes osseous growth and destruction driven by alterations in osteoblast and osteoclast homeostasis. Patients can experience pain, spontaneous fractures and morbidity eroding overa
Externí odkaz:
https://doaj.org/article/4f5abe73610c40c2b93fec33f6a9b7b2
Autor:
Michael G Harrington, Jiarong Chiang, Janice M Pogoda, Megan Gomez, Kris Thomas, Sarah Deboard Marion, Karen J Miller, Prabha Siddarth, Xinyao Yi, Feimeng Zhou, Sherri Lee, Xianghong Arakaki, Robert P Cowan, Thao Tran, Cherise Charleswell, Brian D Ross, Alfred N Fonteh
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79378 (2013)
Early treatment of Alzheimer's disease may reduce its devastating effects. By focusing research on asymptomatic individuals with Alzheimer's disease pathology (the preclinical stage), earlier indicators of disease may be discovered. Decreasing cerebr
Externí odkaz:
https://doaj.org/article/cd514eb71dc542768d7cacc64dcc6f39
Autor:
Stefanie Galbán, Yong Hyun Jeon, Brittany M Bowman, James Stevenson, Katrina A Sebolt, Lisa M Sharkey, Michael Lafferty, Benjamin A Hoff, Braeden L Butler, Susan S Wigdal, Brock F Binkowski, Paul Otto, Kris Zimmerman, Gediminas Vidugiris, Lance P Encell, Frank Fan, Keith V Wood, Craig J Galbán, Brian D Ross, Alnawaz Rehemtulla
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66248 (2013)
In addition to their degradative role in protein turnover, proteases play a key role as positive or negative regulators of signal transduction pathways and therefore their dysregulation contributes to many disease states. Regulatory roles of protease
Externí odkaz:
https://doaj.org/article/92a47bc9999a43418aeead5d0ff96642
Autor:
Stefanie Galbán, Benjamin Lemasson, Terence M Williams, Fei Li, Kevin A Heist, Timothy D Johnson, Judith S Leopold, Thomas L Chenevert, Theodore S Lawrence, Alnawaz Rehemtulla, Tom Mikkelsen, Eric C Holland, Craig J Galbán, Brian D Ross
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35857 (2012)
The effectiveness of the radiosensitizer gemcitabine (GEM) was evaluated in a mouse glioma along with the imaging biomarker diffusion-weighted magnetic resonance imaging (DW-MRI) for early detection of treatment effects. A genetically engineered muri
Externí odkaz:
https://doaj.org/article/500f7f54274e4c979870df1128096dc6
Autor:
Mahaveer S Bhojani, Rajesh Ranga, Gary D Luker, Alnawaz Rehemtulla, Brian D Ross, Marcian E Van Dort
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22418 (2011)
A radioiodinated derivative of the tumor-homing F3 peptide, (N-(2-{3-[(125)I]Iodobenzoyl}aminoethyl)maleimide-F3Cys peptide, [(125)I]IBMF3 was developed for investigation as a SPECT tumor imaging radioligand. For this purpose, we custom synthesized a
Externí odkaz:
https://doaj.org/article/9034939732b34d409b126e6627c1a2fb
Autor:
Kenneth L Pitter, Craig J Galbán, Stefanie Galbán, Omid Saeed Tehrani, Fei Li, Nikki Charles, Michelle S Bradbury, Oren J Becher, Thomas L Chenevert, Alnawaz Rehemtulla, Brian D Ross, Eric C Holland, Dolores Hambardzumyan
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14545 (2011)
Platelet derived growth factor receptor (PDGFR) activity is deregulated in human GBM due to amplification and rearrangement of the PDGFR-alpha gene locus or overexpression of the PDGF ligand, resulting in the activation of downstream kinases such as
Externí odkaz:
https://doaj.org/article/f0de6ec698e144ed93bcf6f25bb88d2e
Autor:
Stephen M. Moore, James D. Quirk, Andrew W. Lassiter, Richard Laforest, Gregory D. Ayers, Cristian T. Badea, Andriy Y. Fedorov, Paul E. Kinahan, Matthew Holbrook, Peder E. Z. Larson, Renuka Sriram, Thomas L. Chenevert, Dariya Malyarenko, John Kurhanewicz, A. McGarry Houghton, Brian D. Ross, Stephen Pickup, James C. Gee, Rong Zhou, Seth T. Gammon, Henry Charles Manning, Raheleh Roudi, Heike E. Daldrup-Link, Michael T. Lewis, Daniel L. Rubin, Thomas E. Yankeelov, Kooresh I. Shoghi
Publikováno v:
Tomography, Vol 9, Iss 3, Pp 995-1009 (2023)
Preclinical imaging is a critical component in translational research with significant complexities in workflow and site differences in deployment. Importantly, the National Cancer Institute’s (NCI) precision medicine initiative emphasizes the use
Externí odkaz:
https://doaj.org/article/c03b45b43e1546d4a22efc4f2e820217
Autor:
Aman Kushwaha, Rami F. Mourad, Kevin Heist, Humera Tariq, Heang-Ping Chan, Brian D. Ross, Thomas L. Chenevert, Dariya Malyarenko, Lubomir M. Hadjiiski
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 589-602 (2023)
A murine model of myelofibrosis in tibia was used in a co-clinical trial to evaluate segmentation methods for application of image-based biomarkers to assess disease status. The dataset (32 mice with 157 3D MRI scans including 49 test–retest pairs
Externí odkaz:
https://doaj.org/article/57bde20f3b714dee9437b49279f3b73a