Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Brian D Plouffe"'
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186116 (2017)
Vasculoprotective endothelium glycocalyx (GCX) shedding plays a critical role in vascular disease. Previous work demonstrated that GCX degradation disrupts endothelial cell (EC) gap junction connexin (Cx) proteins, likely blocking interendothelial mo
Externí odkaz:
https://doaj.org/article/c4b68d44eb2748e2ac5cf5bbab858ac7
Autor:
Franziska Diekmann, Philippe Chouvarine, Hannes Sallmon, Louisa Meyer-Kobbe, Moritz Kieslich, Brian D. Plouffe, Shashi K. Murthy, Ralf Lichtinghagen, Ekaterina Legchenko, Georg Hansmann
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8591 (2021)
Pulmonary arterial hypertension (PAH) is a progressive condition with an unmet need for early diagnosis, better monitoring, and risk stratification. The receptor for advanced glycation end products (RAGE) is activated in response to hypoxia and vascu
Externí odkaz:
https://doaj.org/article/804e8014bdee4c22b9f7657b3bcd5d26
Autor:
Shashi K. Murthy, Brian D. Plouffe
Publikováno v:
ELECTROPHORESIS. 38:501-506
With the recent worldwide changes in the legalization of marijuana, there is a significant need for rapid, roadside screening test for driving under the influence of drugs. A robust, sensitive, lateral flow assay has been developed to detect recent u
Circulating Endothelial Cell Quantification by Microfluidics Chip in Pulmonary Arterial Hypertension
Publikováno v:
American journal of respiratory cell and molecular biology. 56(5)
Autor:
Brian D. Plouffe, Shashi K. Murthy
Publikováno v:
Analytical Chemistry
The purification and sorting of cells using microfluidic methodologies has been a remarkably active area of research over the past decade. Much of the scientific and technological work associated with microfluidic cell separation has been driven by n
Autor:
Johann Bauersachs, Christoph Schroeder, Laurent Calvier, Brian D. Plouffe, Lena Grimm, Shashi K. Murthy, Georg Hansmann, Adam Hatch, Ekaterina Legchenko, Hannes Sallmon
Publikováno v:
The Thoracic and Cardiovascular Surgeon. 64
Several studies have identified circulating biomarkers to be associated with the presence and severity of pulmonary arterial hypertension (PAH). Recent evidence supports a role for galectin-3 (Gal-3) and the mineralcorticoid aldosterone in left ventr
Autor:
Don Heiman, Robert S. DiPietro, Brian D. Plouffe, Lewis H. Lewis, Shashi K. Murthy, Dattatri Nagesha, Srinvas Sridhar
Publikováno v:
Journal of Magnetism and Magnetic Materials. 323:2310-2317
The utility and promise of magnetic nanoparticles (MagNPs) for biomedicine rely heavily on accurate determination of the particle diameter attributes. While the average functional size and size distribution of the magnetic nanoparticles directly impa
Autor:
Adam Hatch, Brian D. Plouffe, Alexander von Gise, Georg Hansmann, Roham T. Zamanian, Shashi K. Murthy, Hannes Sallmon
Publikováno v:
Journal of Molecular Medicine. 89:971-983
The number of circulating endothelial progenitor cells (EPCs) inversely correlates with cardiovascular risk and clinical outcome, and thus has been proposed as a valuable biomarker for risk assessment, disease progression, and response to therapy. Ho
Publikováno v:
The FASEB Journal. 23:3309-3314
We have developed a unique microfluidic platform capable of capturing circulating endothelial progenitor cells (EPCs) by understanding surface chemistries and adhesion profiles. The surface of a variable-shear-stress microfluidic device was conjugate
Autor:
Brian D. Plouffe, Danson N. Njoka, Shashi K. Murthy, Milica Radisic, Nora Horick, Joscelyn Harris, Jiahui Liao
Publikováno v:
Langmuir. 23:5050-5055
Microfluidic devices have recently emerged as effective tools for cell separation compared to traditional techniques. These devices offer the advantages of small sample volumes, low cost, and high purity. Adhesion-based separation of cells from heter