Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Brian D Hondowicz"'
Autor:
Brian D Hondowicz, Katharine V Schwedhelm, Arnold Kas, Michael A Tasch, Crystal Rawlings, Nirasha Ramchurren, Martin McIntosh, Leonard A D'Amico, Srinath Sanda, Nathan E Standifer, Jay Shendure, Brad Stone
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29949 (2012)
The identification of novel T cell antigens is central to basic and translational research in autoimmunity, tumor immunology, transplant immunology, and vaccine design for infectious disease. However, current methods for T cell antigen discovery are
Externí odkaz:
https://doaj.org/article/f2025b1ba27e4c41b1153450df9f697c
Publikováno v:
European Journal of Immunology. 48:80-86
CD4+ tissue resident cells are an important first line of defense against viral infections in the lungs and are critical for promoting the localization of lung resident CD8+ T cells. However, relatively little is known about the signaling programs re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f6315943cb2adf602a5ce52f01f076f
https://doi.org/10.1002/eji.201746928
https://doi.org/10.1002/eji.201746928
Autor:
Dowon An, Gladys J. Keitany, Holly R. Steach, Marion Pepper, Jason M. Schenkel, David Masopust, Akshay T. Krishnamurty, Brian D. Hondowicz, William A. Altemeier, Kathryn A. Fraser, Karen S. Kim, Esteban N. Garza, James J. Moon
Publikováno v:
Immunity. 44(1)
Exposure to inhaled allergens generates T helper 2 (Th2) CD4(+) T cells that contribute to episodes of inflammation associated with asthma. Little is known about allergen-specific Th2 memory cells and their contribution to airway inflammation. We gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7711bb32dd3b0e2593e6fd614e507a72
https://pubmed.ncbi.nlm.nih.gov/26789918
https://pubmed.ncbi.nlm.nih.gov/26789918
Autor:
Brian D. Hondowicz, Shawn T. Alexander, Yangzhu Du, Jan Erikson, Eline T. Luning Prak, Michele L. Fields, Marc Monestier, Alice C. Hsu, Michele H. Metzgar, Sun-Ah Kang, Kristin D. Hazard
Publikováno v:
The Journal of Immunology. 176:6491-6502
Autoreactive B cells may become activated in a T-independent manner via synergistic engagement of the BCR and TLRs. Using the VH3H9 Ig H chain transgene to track anti-chromatin B cells, we demonstrate that VH3H9/Vλ1 anti-chromatin B cells proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f01b108858de3a603796dc9bf21103
https://doi.org/10.4049/jimmunol.176.11.6491
https://doi.org/10.4049/jimmunol.176.11.6491
Autor:
Gina N. Wharton, Cristina Cozzo Picca, Jan Erikson, Michele H. Metzgar, Michele L. Fields, Brian D. Hondowicz, Simone A. Nish, Andrew J. Caton
Publikováno v:
The Journal of Immunology. 175:4255-4264
To investigate the mechanism by which T regulatory (Treg) cells may control the early onset of autoimmunity, we have used an adoptive transfer model to track Treg, Th, and anti-chromatin B cell interactions in vivo. We show that anti-chromatin B cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd583331d899b93987401a7f59f1083
https://doi.org/10.4049/jimmunol.175.7.4255
https://doi.org/10.4049/jimmunol.175.7.4255
Autor:
Jan Erikson, Michele L. Fields, Simone A. Nish, Brian D. Hondowicz, Michele H. Metzgar, Andrew J. Caton, Gina N. Wharton
Publikováno v:
The Journal of Immunology. 175:104-111
Circulating autoantibodies against dsDNA and chromatin are a characteristic of systemic lupus erythematosus in humans and many mouse models of this disease. B cells expressing these autoantibodies are normally regulated in nonautoimmune-prone mice bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17ba04d489d981bf8235f31940f4da4e
https://doi.org/10.4049/jimmunol.175.1.104
https://doi.org/10.4049/jimmunol.175.1.104
Autor:
Andrew J. Caton, Jan Erikson, Michele H. Metzgar, Brigette S. Adair, Brian D. Hondowicz, Shawn T. Alexander, Michele L. Fields, Gina N. Wharton
Publikováno v:
Immunological Reviews. 204:165-183
Anti-double-stranded DNA (anti-dsDNA) B cells are regulated in non-autoimmune mice. While some are deleted or undergo receptor editing, a population of anti-dsDNA (VH3H9/V lambda 1) B cells that emigrate into the periphery has also been identified. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597cf48c1544751c8a346d13f223a68f
https://doi.org/10.1111/j.0105-2896.2005.00238.x
https://doi.org/10.1111/j.0105-2896.2005.00238.x
Autor:
Arnold Kas, Srinath Sanda, Brad Stone, Jay Shendure, Katharine Schwedhelm, Martin W. McIntosh, Nirasha Ramchurren, Leonard A. D'Amico, Michael Tasch, Brian D. Hondowicz, Crystal Rawlings, Nathan Standifer
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29949 (2012)
PLoS ONE
PLoS ONE
The identification of novel T cell antigens is central to basic and translational research in autoimmunity, tumor immunology, transplant immunology, and vaccine design for infectious disease. However, current methods for T cell antigen discovery are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e714c4a80935e8f71fbbf2ce8932904a
http://europepmc.org/articles/PMC3257230?pdf=render
http://europepmc.org/articles/PMC3257230?pdf=render
Autor:
Amrita O. Batheja, Jan Erikson, Antonio J. Pagán, Andrew J. Caton, Michele H. Metzgar, Simone Willms, Olivia A. Perng, Brian D. Hondowicz
Publikováno v:
European journal of immunology. 39(9)
T-cell recognition of peptide/MHC complexes is flexible and can lead to differential activation, but how interactions with agonist (full activation) or partial agonist (suboptimal activation) peptides can shape immune responses in vivo is not well ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df6f957124cb89cf003dda7232cb067e
https://pubmed.ncbi.nlm.nih.gov/19662636
https://pubmed.ncbi.nlm.nih.gov/19662636
Autor:
Brian D. Hondowicz, Simone A. Nish, Jan Erikson, Andrew J. Caton, Joseph Larkin, Michele L. Fields
Publikováno v:
Journal of autoimmunity. 31(2)
In Fas/FasL-deficient mice anti-chromatin Ab production is T cell dependent and is not apparent until after 10 weeks of age. Early control of anti-chromatin antibodies may be due to the counterbalancing influence of Treg cells. Here we show that Treg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bed0c43fbd32bdbecfcb43d583af8e1
https://pubmed.ncbi.nlm.nih.gov/18539433
https://pubmed.ncbi.nlm.nih.gov/18539433