Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Brian D, Williamson"'
Autor:
Craig A. Magaret, Li Li, Allan C. deCamp, Morgane Rolland, Michal Juraska, Brian D. Williamson, James Ludwig, Cindy Molitor, David Benkeser, Alex Luedtke, Brian Simpkins, Fei Heng, Yanqing Sun, Lindsay N. Carpp, Hongjun Bai, Bethany L. Dearlove, Elena E. Giorgi, Mandy Jongeneelen, Boerries Brandenburg, Matthew McCallum, John E. Bowen, David Veesler, Jerald Sadoff, Glenda E. Gray, Sanne Roels, An Vandebosch, Daniel J. Stieh, Mathieu Le Gars, Johan Vingerhoets, Beatriz Grinsztejn, Paul A. Goepfert, Leonardo Paiva de Sousa, Mayara Secco Torres Silva, Martin Casapia, Marcelo H. Losso, Susan J. Little, Aditya Gaur, Linda-Gail Bekker, Nigel Garrett, Carla Truyers, Ilse Van Dromme, Edith Swann, Mary A. Marovich, Dean Follmann, Kathleen M. Neuzil, Lawrence Corey, Alexander L. Greninger, Pavitra Roychoudhury, Ollivier Hyrien, Peter B. Gilbert
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract In the ENSEMBLE randomized, placebo-controlled phase 3 trial (NCT04505722), estimated single-dose Ad26.COV2.S vaccine efficacy (VE) was 56% against moderate to severe–critical COVID-19. SARS-CoV-2 Spike sequences were determined from 484 v
Externí odkaz:
https://doaj.org/article/ae82624b40e944a5925f8f3c70ded9b7
Autor:
Sandi L. Navarro, Brian D. Williamson, Ying Huang, G. A. Nagana Gowda, Daniel Raftery, Lesley F. Tinker, Cheng Zheng, Shirley A. A. Beresford, Hayley Purcell, Danijel Djukovic, Haiwei Gu, Howard D. Strickler, Fred K. Tabung, Ross L. Prentice, Marian L. Neuhouser, Johanna W. Lampe
Publikováno v:
Metabolites, Vol 14, Iss 8, p 463 (2024)
Metabolomics has been used extensively to capture the exposome. We investigated whether prospectively measured metabolites provided predictive power beyond well-established risk factors among 758 women with adjudicated cancers [n = 577 breast (BC) an
Externí odkaz:
https://doaj.org/article/ee0a525611cb46a093caf9512b504bd6
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0310042 (2024)
Combination monoclonal broadly neutralizing antibodies (bnAbs) are currently being developed for preventing HIV-1 acquisition. Recent work has focused on predicting in vitro neutralization potency of both individual bnAbs and combination regimens aga
Externí odkaz:
https://doaj.org/article/093a96afaadf49dd990fb774664ec753
Autor:
Benjamin H. Balderson, Shelly L. Gray, Monica M. Fujii, Kanichi G. Nakata, Brian D. Williamson, Andrea J. Cook, Robert Wellman, Mary Kay Theis, Cara C. Lewis, Dustin Key, Elizabeth A. Phelan
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Central nervous system (CNS) active medications have been consistently linked to falls in older people. However, few randomized trials have evaluated whether CNS-active medication reduction reduces falls and fall-related injuries.
Externí odkaz:
https://doaj.org/article/5eb1fa1251d2461686f73832f4e54a65
Autor:
Brian D. Williamson, Craig A. Magaret, Shelly Karuna, Lindsay N. Carpp, Huub C. Gelderblom, Yunda Huang, David Benkeser, Peter B. Gilbert
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107595- (2023)
Summary: Combination monoclonal broadly neutralizing antibody (bnAb) regimens are in clinical development for HIV prevention, necessitating additional knowledge of bnAb neutralization potency/breadth against circulating viruses. Williamson et al. (20
Externí odkaz:
https://doaj.org/article/6643c1ff735844fdb145351d0dac803d
Autor:
Lauren E. Dang, Susan Gruber, Hana Lee, Issa J. Dahabreh, Elizabeth A. Stuart, Brian D. Williamson, Richard Wyss, Iván Díaz, Debashis Ghosh, Emre Kıcıman, Demissie Alemayehu, Katherine L. Hoffman, Carla Y. Vossen, Raymond A. Huml, Henrik Ravn, Kajsa Kvist, Richard Pratley, Mei-Chiung Shih, Gene Pennello, David Martin, Salina P. Waddy, Charles E. Barr, Mouna Akacha, John B. Buse, Mark van der Laan, Maya Petersen
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Increasing emphasis on the use of real-world evidence (RWE) to support clinical policy and regulatory decision-making has led to a proliferation of guidance, advice, and frameworks from regulatory agencies, academia, professional societies, and indus
Externí odkaz:
https://doaj.org/article/1b066ab2c2c342e3b214a06e4b384ce1
Autor:
Brian D. Williamson, Richard Wyss, Elizabeth A. Stuart, Lauren E. Dang, Andrew N. Mertens, Romain S. Neugebauer, Andrew Wilson, Susan Gruber
Publikováno v:
Journal of Clinical and Translational Science, Vol 7 (2023)
Abstract Background: Real-world data, such as administrative claims and electronic health records, are increasingly used for safety monitoring and to help guide regulatory decision-making. In these settings, it is important to document analytic deci
Externí odkaz:
https://doaj.org/article/9ea4294e22584aec91098abda19a1f28
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background While random forests are one of the most successful machine learning methods, it is necessary to optimize their performance for use with datasets resulting from a two-phase sampling design with a small number of cases—a common s
Externí odkaz:
https://doaj.org/article/59888be2e459495c93e907d674a72e1a
Autor:
Yunda Huang, Yuanyuan Zhang, Kelly E. Seaton, Stephen De Rosa, Jack Heptinstall, Lindsay N. Carpp, April Kaur Randhawa, Lyle R. McKinnon, Paul McLaren, Edna Viegas, Glenda E. Gray, Gavin Churchyard, Susan P. Buchbinder, Srilatha Edupuganti, Linda-Gail Bekker, Michael C. Keefer, Mina C. Hosseinipour, Paul A. Goepfert, Kristen W. Cohen, Brian D. Williamson, M. Juliana McElrath, Georgia D. Tomaras, Juilee Thakar, James J. Kobie
Publikováno v:
EBioMedicine, Vol 84, Iss , Pp 104271- (2022)
Summary: Background: The identification of baseline host determinants that associate with robust HIV-1 vaccine-induced immune responses could aid HIV-1 vaccine development. We aimed to assess both the collective and relative performance of baseline c
Externí odkaz:
https://doaj.org/article/fadb3c4955a04c03b07eef2fa43a9e8d
Autor:
Michael J. Gallagher, Richard Bloomingdale, Aaron D. Berman, Brian D. Williamson, Simon R. Dixon, Robert D. Safian
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 14 (2020)
Abstract Coronavirus disease 2019 is a global pandemic affecting >3 million people in >170 countries, resulting in >200 000 deaths; 35% to 40% of patients and deaths are in the United States. The coronavirus disease 2019 crisis is placing an enormous
Externí odkaz:
https://doaj.org/article/a1156b5ce7d548949df3eb1cf096e7f6