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of 163
pro vyhledávání: '"Brian D, Tait"'
Autor:
Brian D. Tait
Publikováno v:
Exploration of Immunology, Vol 4, Iss 5, Pp 568-576 (2024)
Type I diabetes susceptibility is caused by both environmental and genetic factors, the latter comprising approximately half of the total risk as evidenced by the fact that identical twins have approximately 50% concordance, suggesting 50% of the dis
Externí odkaz:
https://doaj.org/article/cc3f0476eed042d9bad0b73bea704971
Autor:
Brian D, Tait
Publikováno v:
International Journal of Immunogenetics. 49:1-7
Haplotyping or determination of genetic phase has always played a pivotal role in MHC (HLA studies) both in helping to understand inheritance patterns in diseases such as type 1 diabetes (T1D) and in ensuring better matching in transplantation scenar
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Externí odkaz:
https://doaj.org/article/e09d8616a8c741538fc460665f8784b7
Autor:
Judith Field, Sharon R Browning, Laura J Johnson, Patrick Danoy, Michael D Varney, Brian D Tait, Kaushal S Gandhi, Jac C Charlesworth, Robert N Heard, Australia and New Zealand Multiple Sclerosis Genetics Consortium, Graeme J Stewart, Trevor J Kilpatrick, Simon J Foote, Melanie Bahlo, Helmut Butzkueven, James Wiley, David R Booth, Bruce V Taylor, Matthew A Brown, Justin P Rubio, Jim Stankovich
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13454 (2010)
We conducted an association study across the human leukocyte antigen (HLA) complex to identify loci associated with multiple sclerosis (MS). Comparing 1927 SNPs in 1618 MS cases and 3413 controls of European ancestry, we identified seven SNPs that we
Externí odkaz:
https://doaj.org/article/666c12ee17314e0d830ff51e46de6064
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology, Vol 8 (2017)
Autor:
David C Sayer, Brian D. Tait, Abha Chopra, Lavinia Gordon, Fernando J. Rossello, Ming Je Hsieh, Colin W. Pouton, Helen Irving, David R. Powell, Matthew J. Burton, D. Cooper, Nicholas M. Murphy, Mark D. Pertile
Publikováno v:
Scientific Reports
We describe a method for determining the parental HLA haplotypes of a single individual without recourse to conventional segregation genetics. Blood samples were cultured to identify and sort chromosome 6 by bivariate flow cytometry. Single chromosom
Autor:
June J Pierce, David M. Reboussin, Letitia H Perdue, Anthony Louey, Julie A. Lane, Jeff Post, Sean Boyle, Dustin T. Williams, Joan E. Hilner, Beena Akolkar, Michael D. Varney, Wolfgang Helmberg, P. V. Moonsamy, Persia Bonella, Rebecca Rappner, Janelle A. Noble, Henry A. Erlich, Josyf C. Mychaleckyj, Paul Sali, Eva Lavant, Samuel Kim, T Dgc, Michael W. Steffes, Anna Lisa Fear, Joyce Carlson, Brian D. Tait
Publikováno v:
Clinical Trials (London, England)
Background Although human leukocyte antigen (HLA) DQ and DR loci appear to confer the strongest genetic risk for type 1 diabetes, more detailed information is required for other loci within the HLA region to understand causality and stratify addition
Autor:
Josyf C. Mychaleckyj, Brian D. Tait, Henry A. Erlich, Ana M. Valdes, Eva Lavant, Anthony Louey, Persia Bonella, P. V. Moonsamy, Joyce Carlson, Janelle A. Noble, Anna Lisa Fear, Michael D. Varney
Publikováno v:
Diabetes. 59:2055-2062
OBJECTIVETo determine the relative risk associated with DPA1 and DPB1 alleles and haplotypes in type 1 diabetes.RESEARCH DESIGN AND METHODSThe frequency of DPA1 and DPB1 alleles and haplotypes in type 1 diabetic patients was compared to the family ba
Autor:
Simon J. Foote, Mark Marriott, Niall Tubridy, Brian D. Tait, Bruce V. Taylor, Jim Stankovich, C. Chapman, Trevor J. Kilpatrick, Michael D. Varney, Justin P. Rubio, Helmut Butzkueven
Publikováno v:
Tissue Antigens. 74:17-21
Human leucocyte antigen (HLA)-DRB1*1501 and other class II alleles influence susceptibility to multiple sclerosis (MS), but their contribution if any to the clinical course of MS remains uncertain. Here, we have investigated DRB1 alleles in a large s
Autor:
Fiona Hudson, Peter G. Kerr, Brian D. Tait, John Kanellis, John P. Dowling, Alison Skene, William R. Mulley
Publikováno v:
Transplantation. 87:286-289
Rituximab may improve graft survival in renal acute antibody-mediated rejection (AMR), but data confirming efficacy and optimal dosing is lacking. High-dose regimens may be associated with significant rates of infective complications. We therefore co