Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Brian D, Polizzotti"'
Autor:
Sayemul Islam, Rebecca C. Huggins, Abdulaziz N. A. E. Almeseri, Michael Domic, Seung Hyun Song, Brian D. Polizzotti, Albert Kim
Publikováno v:
IEEE Transactions on Biomedical Engineering. 70:1380-1388
Hypoxia and hypoxemia are the conditions when oxygen is depleted from the cell due to, for example, respiratory failure, cancer, etc. While the current therapy brought reasonable clinical outcomes, its systematic nature of oxygen delivery can be comp
Autor:
David C. Zebrowski, Charlotte H. Jensen, Robert Becker, Fulvia Ferrazzi, Christina Baun, Svend Hvidsten, Søren P. Sheikh, Brian D. Polizzotti, Ditte C. Andersen, Felix B. Engel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract After birth cardiomyocytes undergo terminal differentiation, characterized by binucleation and centrosome disassembly, rendering the heart unable to regenerate. Yet, it has been suggested that newborn mammals regenerate their hearts after ap
Externí odkaz:
https://doaj.org/article/e7d8aee405594a0083d3e1c9ea9c1ef3
Autor:
Ryan Patenaude, Sayeda Yasmin-Karim, Yifeng Peng, Kai W. Wucherpfennig, Wifred Ngwa, John N. Kheir, Brian D. Polizzotti
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics.
Autor:
Brian D. Polizzotti, John N. Kheir, Nathan McDannold, Tao Sun, Yifeng Peng, Tien Nguyen, Chenguang Peng, Tyrone M. Porter
Publikováno v:
ACS Materials Letters. 3:978-987
Autor:
Ashwin Kumar Vutha, Ryan Patenaude, Alexis Cole, Rajesh Kumar, John N. Kheir, Brian D. Polizzotti
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance The treatment of hypoxemia that is refractory to the current standard of care is time-sensitive and requires skilled caregivers and use of specialized equipment (e.g., extracorporeal membrane oxygenation). Most patients experiencing refr
Autor:
Kevin Bersell, Sangita Choudhury, Mariya Mollova, Brian D. Polizzotti, Balakrishnan Ganapathy, Stuart Walsh, Brian Wadugu, Shima Arab, Bernhard Kühn
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 6, Pp 1459-1469 (2013)
SUMMARY Numerous mouse models have utilized Cre-loxP technology to modify gene expression. Adverse effects of Cre recombinase activity have been reported, including in the heart. However, the mechanisms associated with cardiac Cre toxicity are largel
Externí odkaz:
https://doaj.org/article/f1ba5260553c4419b0f397239307fecf
Autor:
Balakrishnan Ganapathy, Nikitha Nandhagopal, Brian D Polizzotti, David Bennett, Alparslan Asan, Yijen Wu, Bernhard Kühn
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155456 (2016)
BACKGROUND:We previously developed and validated a strategy for stimulating heart regeneration by administration of recombinant neuregulin (rNRG1), a growth factor, in mice. rNRG1 stimulated proliferation of heart muscle cells, cardiomyocytes, and wa
Externí odkaz:
https://doaj.org/article/5c29601be6df4c94a87b315224a8e42b
Autor:
Daniel P, Erdosy, Malia B, Wenny, Joy, Cho, Christopher, DelRe, Miranda V, Walter, Felipe, Jiménez-Ángeles, Baofu, Qiao, Ricardo, Sanchez, Yifeng, Peng, Brian D, Polizzotti, Monica Olvera, de la Cruz, Jarad A, Mason
Publikováno v:
Nature. 608(7924)
Liquids with permanent microporosity can absorb larger quantities of gas molecules than conventional solvents
Autor:
Ali Raza, John N. Kheir, Brian D. Polizzotti, Humera Ahmed, Robert F. Padera, Alexis R. Cole, Nick Andrews
Publikováno v:
Medical Gas Research
The purpose of this work was to determine the safety of inhaled hydrogen gas in healthy animals. Female mice were exposed to medical air with or without hydrogen gas (concentration 2.4%) for 72 hours (n = 25 mice/group). Mice underwent a standardized
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36788 (2012)
Administration of a recombinant peptide of Periostin (rPN) has recently been shown to stimulate cardiomyocyte proliferation and angiogenesis after myocardial infarction (MI) [1]. However, strategies for targeting the delivery of rPN to the heart are
Externí odkaz:
https://doaj.org/article/6868cffae385493782a6b900e1059f66