Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Brian D, Lowes"'
Autor:
Philip D. Tatman, David P. Kao, Kathryn C. Chatfield, Ian A. Carroll, Jessica A. Wagner, Eric R. Jonas, Carmen C. Sucharov, J. David Port, Brian D. Lowes, Wayne A. Minobe, Sophia P. Huebler, Anis Karimpour-Fard, Erin M. Rodriguez, Stephen B. Liggett, Michael R. Bristow
Publikováno v:
JCI Insight, Vol 8, Iss 16 (2023)
We investigated the extent, biologic characterization, phenotypic specificity, and possible regulation of a β1-adrenergic receptor–linked (β1-AR–linked) gene signaling network (β1-GSN) involved in left ventricular (LV) eccentric pathologic rem
Externí odkaz:
https://doaj.org/article/cc7c56d0fed841659469accaddf4f47a
Publikováno v:
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Cigarette smoking is an important risk factor for cardiac diseases. In the current study, we sought to assess the effect of electronic cigarette extract (ECE) and conventional cigarette smoke extract (CSE) on cardiomyocytes. Metho
Externí odkaz:
https://doaj.org/article/1f3f30c513c8445a8a7296ec810df4e8
Autor:
Kajari Dhar, Asmini KC, Fang Qiu, Hesham Basma, Krupa K. Savalia, Jocelyn Jones, Alexandra M. Moulton, Matthew C. Zimmerman, John Um, Daniel Anderson, Marshall Hyden, Brian D. Lowes
Publikováno v:
Translational Medicine Communications, Vol 5, Iss 1, Pp 1-10 (2020)
Abstract Background Myocardial recovery with Left ventricular assistant device (LVAD) therapy is dichotomous with some patients obtaining remission from end-stage heart failure whereas most require transplantation or remain on pump support long term.
Externí odkaz:
https://doaj.org/article/4f1d86d99b9541b2a1f86a51adf16777
Autor:
Scott W. Lundgren, DO, Brian D. Lowes, MD, PhD, Elizabeth Lyden, MS, Ronald Zolty, MD, PhD, Adam Burdorf, DO, MS, Marshall Hyden, MD, John Um, MD, Douglas A. Stoller, MD, PhD
Publikováno v:
Transplantation Direct, Vol 7, Iss 10, p e752 (2021)
Introduction. Although pulmonary function testing (PFT) is typically performed for heart transplant evaluation, the prognostic utility of PFTs after transplantation is unknown. We evaluated whether PFT parameters were correlated with outcomes followi
Externí odkaz:
https://doaj.org/article/09d51326738c40049d551c53b849607a
Autor:
Hesham Basma, Adelaide N. Johanson, Kajari Dhar, Daniel Anderson, Fang Qiu, Stephen Rennard, Brian D. Lowes
Publikováno v:
Heliyon, Vol 5, Iss 10, Pp e02633- (2019)
Purpose: The mechanisms for persistent and progressive loss of myocardial function in advanced heart failure (HF) remain incompletely characterized. In the current study, we sought to determine the impact of TGF-β on fibroblasts transcriptional prof
Externí odkaz:
https://doaj.org/article/45a505f25b1740888d624473d6b2b998
Autor:
Muhannad Aboud Abbasi, Douglas A Stoller, Elizabeth Lyden, Brian D Lowes, Ronald Zolty, Scott W Lundgren
Publikováno v:
The International Journal of Artificial Organs. 45:919-926
Introduction: We aimed to assess the impact of digoxin use following left ventricular assist device (LVAD) implantation on clinical outcomes. Methods: Patients implanted with continuous flow LVADs at a single academic medical center and survived to i
Autor:
Kajari Dhar, Alexandra M. Moulton, Eric Rome, Fang Qiu, Jeff Kittrell, Eugenia Raichlin, Ronald Zolty, John Y. Um, Michael J. Moulton, Hesham Basma, Daniel R. Anderson, James D. Eudy, Brian D. Lowes
Publikováno v:
Journal of Translational Medicine, Vol 14, Iss 1, Pp 1-9 (2016)
Abstract Background Myocardial recovery with left ventricular assist device (LVAD) therapy is highly variable and difficult to predict. Next generation ribonucleic acid (RNA) sequencing is an innovative, rapid, and quantitative approach to gene expre
Externí odkaz:
https://doaj.org/article/a631875d5b0a4987b96d66e8e3f107fc
Autor:
Lee S Toni, Ian A Carroll, Kenneth L Jones, Jessica A Schwisow, Wayne A Minobe, Erin M Rodriguez, Natasha L Altman, Brian D Lowes, Edward M Gilbert, Peter M Buttrick, David P Kao, Michael R Bristow
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224389 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0221519.].
Externí odkaz:
https://doaj.org/article/ed2c4301d6cf4e07ba9c56f9f4108260
Autor:
Lee S Toni, Ian A Carroll, Kenneth L Jones, Jessica A Schwisow, Wayne A Minobe, Erin M Rodriguez, Natasha L Altman, Brian D Lowes, Edward M Gilbert, Peter M Buttrick, David P Kao, Michael R Bristow
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221519 (2019)
ObjectivesTo investigate the biologic relevance of cross-platform concordant changes in gene expression in intact human failing/hypertrophied ventricular myocardium undergoing reverse remodeling.BackgroundInformation is lacking on genes and networks
Externí odkaz:
https://doaj.org/article/7689344aac8444d89351ca8992b0d887
Autor:
Marian Urban, Morgan Moody, Elizabeth Lyden, Lecia Kinen, Anthony W. Castleberry, Aleem Siddique, Brian D. Lowes, Douglas A. Stoller, Scott W. Lungren, John Y. Um
Publikováno v:
Clinical Transplantation. 37