Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Brian D, Gray"'
Autor:
Hans Minderman, Maulasri Bhatta, Gautam N Shenoy, Jenni L Loyall, Brian D Gray, Meghana Bapardekar, Alexis Conway, Raymond J Kelleher Jr, Beatriz M Carreno, Gerald Linette, Leonard D Shultz, Sathy V Balu-Iyer, Koon Yan Pak, Richard B Bankert
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Externí odkaz:
https://doaj.org/article/459c116054b34eebac5200ea18da9508
Autor:
Ahmet Kaynak, Harold W. Davis, Subrahmanya D. Vallabhapurapu, Koon Y. Pak, Brian D. Gray, Xiaoyang Qi
Publikováno v:
Pharmaceuticals, Vol 14, Iss 11, p 1193 (2021)
Glioblastoma multiforme (GBM), the most common type of brain cancer, is extremely aggressive and has a dreadful prognosis. GBM comprises 60% of adult brain tumors and the 5 year survival rate of GBM patients is only 4.3%. Standard-of-care treatment i
Externí odkaz:
https://doaj.org/article/002c267e965e47ffbe8ff6e7ce906e59
Autor:
Harold W. Davis, Subrahmanya D. Vallabhapurapu, Zhengtao Chu, Michael A. Wyder, Kenneth D. Greis, Venette Fannin, Ying Sun, Pankaj B. Desai, Koon Y. Pak, Brian D. Gray, Xiaoyang Qi
Publikováno v:
Cells, Vol 9, Iss 9, p 1960 (2020)
Glioblastoma multiforme (GBM), a common type of brain cancer, has a very poor prognosis. In general, viable GBM cells exhibit elevated phosphatidylserine (PS) on their membrane surface compared to healthy cells. We have developed a drug, saposin C-di
Externí odkaz:
https://doaj.org/article/d8d42fb3d44246a289e85d2ce7e47e28
Autor:
Diego R. Martin, Li Wan, Zheng Li, James M. Woolfenden, Koon Y. Pak, Christy Barber, Brian D. Gray, Zhonglin Liu, Rongguang Liang, Lars R. Furenlid
Publikováno v:
Molecular Imaging and Biology. 25:133-143
PURPOSE Previous studies indicate that 99mTc- and fluorescent-labeled c[Cys-Thr-Pro-Ser-Pro-Phe-Ser-His-Cys]OH (TCP-1) peptides were able to detect colorectal cancer (CRC) and tumor-associated vasculature. This study was designed to characterize the
Autor:
Anne Rix, Anna Mrugalla, Natascha Drude, E. Fiegle, Fabian Kiessling, Brian D. Gray, Koon Y. Pak, Felix M. Mottaghy, Wiltrud Lederle, Rene Tolba, H.-J. Kaiser, F. Baskaya
Publikováno v:
Molecular Imaging and Biology, 22(3), 623-633. Springer
PURPOSE: Evaluation of [68Ga]NODAGA-duramycin as a positron emission tomography (PET) tracer of cell death for whole-body detection of chemotherapy-induced organ toxicity.PROCEDURES: Tracer specificity of Ga-68 labeled NODAGA-duramycin was determined
Autor:
Xiaoyang Qi, Subrahmanya D. Vallabhapurapu, Brian D. Gray, Harold W. Davis, Ahmet Kaynak, Koon Y. Pak
Publikováno v:
Pharmaceuticals, Vol 14, Iss 1193, p 1193 (2021)
Pharmaceuticals
Pharmaceuticals
Glioblastoma multiforme (GBM), the most common type of brain cancer, is extremely aggressive and has a dreadful prognosis. GBM comprises 60% of adult brain tumors and the 5 year survival rate of GBM patients is only 4.3%. Standard-of-care treatment i
Autor:
Meghana V. Bapardekar, Gautam N Shenoy, Leonard D. Shultz, Gerald P. Linette, Koon Y. Pak, Sathy V. Balu-Iyer, Richard B. Bankert, Maulasri Bhatta, Hans Minderman, Jenni L Loyall, Brian D. Gray, Alexis Conway, Beatriz M. Carreno, Kunle Odunsi, Raymond J. Kelleher
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 10 (2021)
BackgroundThe human tumor microenvironment (TME) is a complex and dynamic milieu of diverse acellular and cellular components, creating an immunosuppressive environment, which contributes to tumor progression. We have previously shown that phosphatid
Publikováno v:
ACS sensors. 6(10)
Surgical resection of cancerous tissues is a critical procedure for solid tumor treatment. During the operation, the surgeon mostly identifies the cancerous tissues by naked-eye visualization under white light without aid, therefore, the outcome heav
Publikováno v:
Nuclear Medicine and Biology. :23-30
Introduction Both phosphatidylethanolamine (PE) and phosphatidylserine (PS) can be externalized to the outer cell membrane in apoptosis. Thus the objective was to determine whether PE-targeting 18F-duramycin and PS-targeting 18F-Zn-DPA could be used
Autor:
Xiaoyang Qi, Subrahmanya D. Vallabhapurapu, Zhengtao Chu, Michael A. Wyder, Brian D. Gray, Koon Y. Pak, Kenneth D. Greis, Venette Fannin, Pankaj B. Desai, Ying Sun, Harold W. Davis
Publikováno v:
Cells
Volume 9
Issue 9
Cells, Vol 9, Iss 1960, p 1960 (2020)
Volume 9
Issue 9
Cells, Vol 9, Iss 1960, p 1960 (2020)
Glioblastoma multiforme (GBM), a common type of brain cancer, has a very poor prognosis. In general, viable GBM cells exhibit elevated phosphatidylserine (PS) on their membrane surface compared to healthy cells. We have developed a drug, saposin C-di