Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Brian Coles"'
Autor:
Christine B. Ambrosone, Jiyoung Ahn, Keshav K. Singh, Hamed Rezaishiraz, Helena Furberg, Carol Sweeney, Brian Coles, Andrew Trovato
Publikováno v:
Cancer Research. 65:1105-1111
The proximate cause of cancer cell death by radiation therapy and a number of therapeutic agents is through generation of reactive oxygen species, resulting in DNA damage as well as mitochondrial membrane disruption, triggering the apoptotic cascade.
Publikováno v:
Electrochimica Acta. 42:2285-2294
Electrosynthesis provides a novel methodology to produce specific and selective chemical reaction in proteins. Thus electrooxidation of hen egg-white lysozyme (HEWL) at + 1.2 V (vs sce) at a carbon anode in mildly acid buffer produces selective oxida
Autor:
John R. Arrand, Simon N. Stacey, Deborah J. Burt, Brian Coles, Peter L. Stern, Jennifer S. Bartholomew
Publikováno v:
European Journal of Immunology. 24:3175-3179
Human papillomavirus (HPV) DNA encoding the oncogenic proteins E6 and E7 is usually retained in cervical carcinomas, implicating these proteins as potential target antigens for immune recognition in this virally associated tumor. We have characterize
Publikováno v:
Enzyme and Microbial Technology. 16:795-801
Preparative electrooxidation of lysozyme at copper electrodes held at potentials around 1.2 V vs. a saturated calomel reference electrode induces the formation of a yellow chromophore with a concomitant decrease in the pI of the protein. Ion-exchange
Autor:
David J. Meyer, Peter Reinemer, Huili Chen, Brian Coles, Brian Ketterer, Robert Huber, Chulin Xia
Publikováno v:
Biochemical Journal. 293:351-356
Reaction of human GSH transferase P1-1 (GSTP1-1) with diethylpyrocarbonate (DEPC) at pH 7.0 and 4 degrees C resulted in covalent modification of an equivalent of one histidine and one tyrosine residue per subunit, with loss of activity. Sequence anal
Publikováno v:
European Journal of Biochemistry. 214:803-809
The effects of lactogenic hormones on protein secretion by 25.5-G4.2.3 cells, a rat mammary myoepithelial cell line immortalised with a temperature-sensitive T-antigen, were investigated. Insulin, prolactin, estradiol and progesterone had no effect b
Autor:
K S Gilmore, Thomas W. Kensler, Brian Ketterer, David J. Meyer, Jonathan M. Harris, Brian Coles
Publikováno v:
Carcinogenesis. 14:567-572
Male and female Sprague--Dawley rats were maintained for 5 days on control diet or diet containing 0.075% (w/w) 1,2-dithiole-3-thione (D3T) or 5-(2-pyrazinyl)-4-methyl-1,2-dithiole-3-thione (oltipraz). The content of GSH transferase (GST) subunits 1a
Autor:
Brian Coles
Publikováno v:
Research in Science Education. 22:81-90
Routines are a fundamental aspect of classroom life and much attention in recent years has focused on routines for management. The concept of ‘behaviour settings’ and transitions between them as classroom routines is explained and exemplified. Th
Publikováno v:
Scopus-Elsevier
A rat liver mitochondrial-matrix fraction was prepared and shown to have 1-chloro-2,4-dinitrobenzene(CDNB)-metabolizing glutathione transferase (GST) activity. Further fractionation by sequential gel filtration, isoelectric focusing or chromatofocusi
Autor:
Guidalberto Manfioletti, Vincenzo Giancotti, Colyn Crane-Robinson, Pierre Sautiere, Brian Coles, Peter D. Cary, Graham H. Goodwin, Antonella Bandiera, Emanuele Buratti
Publikováno v:
Nucleic Acids Research. 19:6793-6797
The HMGI-C protein is a nuclear phosphoprotein expressed at high levels in transformed cells. The cDNA encoding the mouse protein has been isolated and the sequence of the encoded protein shows that it is related to the HMGY and I proteins, proteins