Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Brian C. VanderVen"'
Autor:
Monique E. Theriault, Davide Pisu, Kaley M. Wilburn, Gabrielle Lê-Bury, Case W. MacNamara, H. Michael Petrassi, Melissa Love, Jeremy M. Rock, Brian C. VanderVen, David G. Russell
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
An inhibitor of Mycobacterium tuberculosis (Mtb) survival acts as an iron chelator, demonstrating that iron deprivation alters Mtb cholesterol and central carbon metabolism.
Externí odkaz:
https://doaj.org/article/ab9219f46bfa49c894494067d5bb497b
Autor:
Pakorn Aiewsakun, Pinidphon Prombutara, Tegar Adriansyah Putra Siregar, Thanida Laopanupong, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Suparerk Borwornpinyo, Pirut Tong-Ngam, Alisa Tubsuwan, Prapaporn Srilohasin, Angkana Chaiprasert, Wuthiwat Ruangchai, Prasit Palittapongarnpim, Therdsak Prammananan, Brian C. VanderVen, Marisa Ponpuak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Tuberculosis is a global public health problem with emergence of multidrug-resistant infections. Previous epidemiological studies of tuberculosis in Thailand have identified a clonal outbreak multidrug-resistant strain of Mycobacterium tuber
Externí odkaz:
https://doaj.org/article/cc4308bcab2248c6a6699842dda13551
Autor:
Thabatta L. S. A. Rosa, Maria Angela M. Marques, Zachary DeBoard, Kelly Hutchins, Carlos Adriano A. Silva, Christine R. Montague, Tianao Yuan, Julio J. Amaral, Georgia C. Atella, Patrícia S. Rosa, Katherine A. Mattos, Brian C. VanderVen, Ramanuj Lahiri, Nicole S. Sampson, Patrick J. Brennan, John T. Belisle, Maria Cristina V. Pessolani, Marcia Berrêdo-Pinho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Externí odkaz:
https://doaj.org/article/b7cdfbc411e443f0854efac06d6e89e4
Autor:
Thabatta L. S. A. Rosa, Maria Angela M. Marques, Zachary DeBoard, Kelly Hutchins, Carlos Adriano A. Silva, Christine R. Montague, Tianao Yuan, Julio J. Amaral, Georgia C. Atella, Patrícia S. Rosa, Katherine A. Mattos, Brian C. VanderVen, Ramanuj Lahiri, Nicole S. Sampson, Patrick J. Brennan, John T. Belisle, Maria Cristina V. Pessolani, Marcia Berrêdo-Pinho
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Upon infection, Mycobacterium leprae, an obligate intracellular bacillus, induces accumulation of cholesterol-enriched lipid droplets (LDs) in Schwann cells (SCs). LDs are promptly recruited to M. leprae-containing phagosomes, and inhibition of this
Externí odkaz:
https://doaj.org/article/8febf0d55d394f6994a5972e33c674cd
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Recent data indicate that the metabolism of Mycobacterium tuberculosis (Mtb) inside its host cell is heavily dependent on cholesterol and fatty acids. Mtb exhibits a unique capacity to co-metabolize different carbon sources and the products
Externí odkaz:
https://doaj.org/article/f6c81e6275fa44bfb16513cf85230f7e
Publikováno v:
Microorganisms, Vol 7, Iss 6, p 177 (2019)
Pathogenic mycobacteria are known for their ability to maintain persistent infections in various mammals. The canonical pathogen in this genus is Mycobacterium tuberculosis and this bacterium is particularly successful at surviving and replicating wi
Externí odkaz:
https://doaj.org/article/bd5c8756a69f4f57bd401010e40e8dc0
Autor:
Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy Rock
Publikováno v:
eLife, Vol 12 (2023)
Cyclic AMP (cAMP) is a ubiquitous second messenger that transduces signals from cellular receptors to downstream effectors. Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis, devotes a considerable amount of coding capacity to p
Externí odkaz:
https://doaj.org/article/fe201b0981a543b4b8b62123b421ec24
Autor:
Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy Rock
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39ed9373da1fe77fee82ffa66145756d
https://doi.org/10.7554/elife.81177.sa2
https://doi.org/10.7554/elife.81177.sa2
Autor:
Kirstin L. Brown, Kaley M. Wilburn, Christine R. Montague, Jason C. Grigg, Olalla Sanz, Esther Pérez-Herrán, David Barros, Lluís Ballell, Brian C. VanderVen, Lindsay D. Eltis
Publikováno v:
Antimicrobial Agents and Chemotherapy. 67
Despite the deployment of combination tuberculosis (TB) chemotherapy, efforts to identify shorter, nonrelapsing treatments have resulted in limited success. Recent evidence indicates that GSK2556286 (GSK286), which acts via Rv1625c, a membrane-bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a674ae15e608cbe3e8cd257613cc6b78
https://doi.org/10.1128/aac.01294-22
https://doi.org/10.1128/aac.01294-22
Autor:
Rachael A. Fieweger, Kaley M. Wilburn, Christine R. Montague, Emma K. Roszkowski, Carolyn M. Kelly, Teresa L. Southard, Holger Sondermann, Evgeniya V. Nazarova, Brian C. VanderVen
Publikováno v:
Journal of Biological Chemistry. 299:102910
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f6cb567852e737b00d82a1752dc9c7d
https://doi.org/10.1016/j.jbc.2023.102910
https://doi.org/10.1016/j.jbc.2023.102910