Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brian C. Duffy"'
Autor:
Sandra Fernandes-Denney, William G. Kerr, Brian C. Duffy, Otto M. Dungan, Daniel Effiong, Shawn Dormann, John D. Chisholm
Publikováno v:
Org Biomol Chem
AQX-1125 is an indane based SHIP1 agonist that has been evaluated in the clinic for the treatment of bladder pain syndrome/interstitial cystitis. To support our own studies on SHIP1 agonists as potential treatments for IBD and Crohn's disease, a new
Publikováno v:
Organic & Biomolecular Chemistry. 14:1623-1628
Alcohols are effectively converted to their corresponding diphenylmethyl (DPM) ethers by reaction with O-diphenylmethyl trichloroacetimidate in refluxing toluene without the requirement of a catalyst or other additives. A number of acid and base sens
Publikováno v:
Tetrahedron Letters. 56:3301-3305
Trichloroacetimidates are displaced with thiols to form the corresponding sulfides without the need for an added acid or base by simply heating the reactants in refluxing THF. This operationally simple procedure provides the corresponding sulfides in
Publikováno v:
Tetrahedron Letters. 55:1994-1997
Proper choice of reaction conditions allows formation of either the quinone or corresponding diquinone as the major product upon treatment of 2-alkyl-1,4-dimethoxybenzenes with ceric ammonium nitrate.
Publikováno v:
ChemInform. 46
Trichloroacetimidates are displaced with thiols to form the corresponding sulfides without the need for an added acid or base by simply heating the reactants in refluxing THF. This operationally simple procedure provides the corresponding sulfides in
Publikováno v:
ChemInform. 45
CAN oxidation of 1,4-dimethoxybenzene derivatives affords quinone or diquinones depending on the solvent employed and the mode of addition.