Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Brian C. Bond"'
Autor:
David Virley, Elena Jazin, Stephen J. Moss, Brian C Bond, Frank S. Walsh, Nigel J. Cairns, Paul Preece, Gary B.T. Moore, Anne W. Mudge, A. Jackie Hunter
Publikováno v:
Molecular Brain Research. 106:101-116
Expression levels of mRNA are commonly measured as a ratio of test to reference gene. The assumption is that reference genes such as β-actin or cyclophilin are unaffected by treatment and act as steady-state controls. TaqMan™ real-time RT-PCR was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::759e2de965bb3d03701a69b92b3645e8
https://doi.org/10.1016/s0169-328x(02)00417-5
https://doi.org/10.1016/s0169-328x(02)00417-5
Publikováno v:
Molecular Brain Research. 90:48-56
The aim of this study was to develop a rapid and accurate high throughput method of screening multiple genes across a single sample set to detect changes in gene expression in the dorsal root ganglion (DRG) following partial sciatic nerve ligation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d86effbbf9212b926be32ffceb34465
https://doi.org/10.1016/s0169-328x(01)00086-9
https://doi.org/10.1016/s0169-328x(01)00086-9
Autor:
Brian C Bond, Robert P. Davis, Karen Louise Philpott, Michael F. James, Colin A. Campbell, David C. Harrison, Andrew A. Parsons
Publikováno v:
Molecular Brain Research. 89:133-146
Proteins of the caspase family are involved in the signalling pathway that ultimately leads to programmed cell death (apoptosis), which has been reported to occur in some experimental models of stroke. In a previous paper we used quantitative reverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ffbec8d4336b9581df5d2d2b557efed
https://doi.org/10.1016/s0169-328x(01)00058-4
https://doi.org/10.1016/s0169-328x(01)00058-4
Autor:
Andrew D. Medhurst, Brian C Bond, Colin A. Campbell, Karen Louise Philpott, Robert P. Davis, David C. Harrison
Publikováno v:
Molecular Brain Research. 75:143-149
Quantitative reverse transcription and polymerisation chain reaction (RT-PCR) using Taqman¿trade mark omitted¿ fluorogenic probes has been used to measure changes in gene expression in the cerebral cortex of rats in the permanent middle cerebral ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2471467fe8e86636403cddd156dcdf
https://doi.org/10.1016/s0169-328x(99)00305-8
https://doi.org/10.1016/s0169-328x(99)00305-8
Autor:
Melanie J. Robbins, Andrew R. Lloyd, Hannah M Critchlow, James D. Clarke, Peter R. Maycox, Declan N.C. Jones, Brian C Bond, Jackie Cilia
Publikováno v:
Journal of psychopharmacology (Oxford, England). 22(5)
Antipsychotic drugs have been shown to modulate immediate early gene (IEG) expression in rat brain regions that are associated with schizophrenia, which may be directly linked to their immediate therapeutic benefit. In this study, we analysed the exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad97bd186202116fc726f0ea92563ea
https://pubmed.ncbi.nlm.nih.gov/18208916
https://pubmed.ncbi.nlm.nih.gov/18208916
Autor:
Jeff L. Mooney, Elizabeth C. Jazwinska, Michael R. Barnes, Mark Hurle, Connie L. Erickson-Miller, Hugh M Davis, William V. Williams, Uma Prabhakar, Theresa M. Conway, Elizabeth I. Valoret, Larry D. Greller, Brian C. Bond, Valeriu Damian-Iordachi, Diane K. Jorkasky, Zhong Li, Andrew P. Stubbs, Blanche Levitt, Paul R. Murdock, Frank L. Tobin, Lisa Cass, Priti Hedge, Steve Clark
Publikováno v:
DNA and cell biology. 24(7)
Administration of endotoxin (LPS) in humans results in profound physiological responses, including activation of peripheral blood mononuclear cells and the release of inflammatory factors. The time course of the response of selected inflammatory prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe3672c3dbae2c1f3e2ee574823d8c9
https://pubmed.ncbi.nlm.nih.gov/16008510
https://pubmed.ncbi.nlm.nih.gov/16008510
Autor:
David C, Harrison, Brian C, Bond
Publikováno v:
Methods in molecular medicine. 104
Many researchers have sought to study changes in gene expression in preclinical models of stroke. These range from in vitro models of ischemia, neuronal death, and regeneration to in vivo animal models aimed at replicating pathologies and regenerativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e77cb196d7b24ce0f2901858e475735b
https://pubmed.ncbi.nlm.nih.gov/15454673
https://pubmed.ncbi.nlm.nih.gov/15454673
Autor:
David C. Harrison, Brian C Bond
Many researchers have sought to study changes in gene expression in preclinical models of stroke. These range from in vitro models of ischemia, neuronal death, and regeneration to in vivo animal models aimed at replicating pathologies and regenerativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cad29ee2c66aa30a7746cae6d14da9d0
https://doi.org/10.1385/1-59259-836-6:265
https://doi.org/10.1385/1-59259-836-6:265
A standard operating procedure for assessing liquid handler performance in high-throughput screening
Autor:
Ricardo Macarron, Robert P. Hertzberg, Andrew J. Pope, Jamie M. Wilson, Clive D. Battle, Nathan Gaul, Yvonne M. Clements, Stacy L. Bartram, Stephen Ashman, Mcallister W Elliott, Brian C. Bond, Juan A. Mostacero, Fernando Ramón, Paul Taylor, Stuart M. Baddeley
Publikováno v:
Journal of biomolecular screening. 7(6)
The thrust of early drug discovery in recent years has been toward the configuration of homogeneous miniaturized assays. This has allowed organizations to contain costs in the face of exponential increases in the number of screening assays that need
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a943f351cf702e632b89bf6f68f699a4
https://pubmed.ncbi.nlm.nih.gov/14599354
https://pubmed.ncbi.nlm.nih.gov/14599354
Publikováno v:
Brain research. 857(1-2)
Death receptors are associated with the homeostatic and pathologic induction of cell death. TR3 is a recently characterised member of the death receptor family that is expressed in the adult brain. In order to establish the role of TR3 in acute CNS d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::601e999a927a82c484bb3bee134061e4
https://pubmed.ncbi.nlm.nih.gov/10700560
https://pubmed.ncbi.nlm.nih.gov/10700560