Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Brian C. Belyea"'
Autor:
Brian C. Belyea, Araceli E. Santiago, Wilson A. Vasconez, Vidya K. Nagalakshmi, Fang Xu, Theodore C. Mehalic, Maria Luisa S. Sequeira-Lopez, R. Ariel Gomez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The hormone renin plays a crucial role in the regulation of blood pressure and fluid-electrolyte homeostasis. Normally, renin is synthesized by juxtaglomerular (JG) cells, a specialized group of myoepithelial cells located near the entrance
Externí odkaz:
https://doaj.org/article/660db11b5d0e49efb6c0e8f6c7c6430b
Purpose: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma of childhood and remains refractory to combined-modality therapy in patients with high risk disease. In skeletal myogenesis, Notch signaling prevents muscle differentiation and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78fa3f13df6dcd86b5dc85f85132363
https://doi.org/10.1158/1078-0432.c.6519921
https://doi.org/10.1158/1078-0432.c.6519921
Autor:
Brian C. Belyea, Fang Xu, Margaret Wiltsie, Hayes Fountain, Jennifer Charlton, Agnes B. Fogo, Maria Luisa Soledad Sequeira-Lopez, Roberto Ariel Gomez
Publikováno v:
Clin Sci (Lond)
Polycystic kidney disease (PKD) is an inherited disorder that results in large kidneys, numerous fluid-filled cysts, and ultimately end-stage kidney disease. PKD is either autosomal dominant caused by mutations in PKD1 or PKD2 genes or autosomal rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93334df8afcad82bde01e4b37792a1e
https://europepmc.org/articles/PMC10052804/
https://europepmc.org/articles/PMC10052804/
Autor:
Maria Luisa S. Sequeira-Lopez, Robert L. Paxton, Douglas W. DeSimone, Hirofumi Watanabe, Bette J. Dzamba, Brian C. Belyea, Minghong Li, R. Ariel Gomez
Publikováno v:
Circ Res
Rationale: Renin-expressing cells are myoendocrine cells crucial for survival. They have been postulated to possess a pressure-sensing mechanism, a baroreceptor, which can detect slight changes in blood pressure and respond with precise and synchroni
Autor:
Rajwinderjit Kaur, Maria Luisa S. Sequeira-Lopez, Brian C. Belyea, Hirofumi Watanabe, Tahagod Mohamed, R. Ariel Gomez, Patrick D. Walker
Publikováno v:
Hypertension
Juxtaglomerular cells are crucial for blood pressure and fluid-electrolyte homeostasis. The factors that maintain the life of renin cells are unknown. In vivo, renin cells receive constant cell-to-cell, mechanical, and neurohumoral stimulation that m
Autor:
Silvia Medrano, Evan A. Brown, Stephen Shang, Mazhar Adli, Turan Tufan, Maria Florencia Martinez, R. Ariel Gomez, Nadia Bertoncello, Omar Guessoum, Maria Luisa S. Sequeira-Lopez, Brian C. Belyea
Publikováno v:
Journal of Clinical Investigation. 128:4787-4803
Renin cells are crucial for survival - they control fluid-electrolyte and blood pressure homeostasis, vascular development, regeneration, and oxygen delivery to tissues. During embryonic development, renin cells are progenitors for multiple cell type