Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Brian C Syverud"'
Publikováno v:
Regenerative Engineering and Translational Medicine. 6:365-372
Volumetric muscle loss (VML) is traumatic, degenerative, or surgical loss of skeletal muscle that exceeds the regenerative capacity of the remaining muscle, thus resulting in impaired muscle function. In humans, the loss of 30% or more mass of any on
Publikováno v:
Regen Eng Transl Med
Volumetric muscle loss (VML) is traumatic, degenerative, or surgical loss of skeletal muscle that exceeds the regenerative capacity of the remaining muscle, thus resulting in impaired muscle function. In humans, the loss of 30% or more mass of any on
Autor:
Lisa M. Larkin, Christopher L. Mendias, Brittany L. Rodriguez, Jonathan P. Gumucio, Shelby E. Florida, Olga M Wroblewski, Brian C Syverud
Publikováno v:
Tissue Engineering Part C: Methods. 24:263-271
The growing deficit in suitable tissues for patients awaiting organ transplants demonstrates the clinical need for engineered tissues as alternative graft sources. Demonstrating safety and efficacy by tracking the migration and fate of implanted cell
Autor:
Alexie A. Larson, Molly N. Pantelic, Shelby E. Florida, Lisa M. Larkin, Brian C Syverud, Brittany L. Rodriguez
Publikováno v:
Cells Tissues Organs. 205:197-207
Our lab showed that administration of dexamethasone (DEX) stimulated myogenesis and resulted in advanced structure in our engineered skeletal muscle units (SMU). While administration of 25 nM DEX resulted in the most advanced structure, 10 nM dosing
Publikováno v:
Tissue Engineering Part C: Methods. 23:616-626
The lack of tools for assessing engineered tissue viability and function in a noninvasive manner is a major regulatory and translational challenge facing tissue engineers. Label-free, nonlinear optical molecular imaging (OMI) has utilized endogenous
Volumetric muscle loss (VML) is a loss of skeletal muscle that results in a sustained impairment of function and is often accompanied by physical deformity. To address the need for more innovative repair options, our laboratory has developed scaffold
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1daa45de0e39b4189e0dd2eb2153735
https://europepmc.org/articles/PMC6583911/
https://europepmc.org/articles/PMC6583911/
Publikováno v:
Tissue engineering. Part C, Methods. 24(1)
Skeletal muscle satellite cells have tremendous therapeutic potential in cell therapy or skeletal muscle tissue engineering. Obtaining a sufficiently pure satellite cell population, however, presents a significant challenge. We hypothesized that size
Publikováno v:
Tissue engineering. Part A. 22(5-6)
Tissue engineered skeletal muscle has potential for application as a graft source for repairing soft tissue injuries, a model for testing pharmaceuticals, and a biomechanical actuator system for soft robots. However, engineered muscle to date has not
Autor:
Angela M. Myers, Brian C Syverud, William M. Kuzon, Keith W VanDusen, Lisa M. Larkin, Ellen M. Arruda, Vasudevan D. Mahalingam
Publikováno v:
Hernia : the journal of hernias and abdominal wall surgery. 21(4)
Evaluation of potential grafts to improve upon current strategies for abdominal wall (AW) repair in small animal models typically involves mechanical testing using methods that currently are inadequate to assess physiologically relevant parameters. T
Publikováno v:
Cells, tissues, organs. 202(3-4)
Tissue-engineered skeletal muscle holds promise as a source of graft tissue for repair of volumetric muscle loss and as a model system for pharmaceutical testing. To reach this potential, engineered tissues must advance past the neonatal phenotype th