Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Brian C Gilger"'
Autor:
Elizabeth Crabtree, Katy Uribe, Sara M Smith, Darby Roberts, Jacklyn H Salmon, Jacquelyn J Bower, Liujiang Song, Prabhakar Bastola, Matthew L Hirsch, Brian C Gilger
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0270972 (2022)
Equine recurrent uveitis (ERU) is a spontaneous, painful, and vision threatening disease affecting up to 25% of equine populations worldwide. Current treatments of ERU are non-specific and have many side effects which limits them to short-term use. I
Externí odkaz:
https://doaj.org/article/09fa11cc71154043970cb391d0db4f03
Autor:
Megan Cullen, Megan E Jacob, Vicki Cornish, Ian Q VanderSchel, Henry Van T Cotter, Marc A Cubeta, Ignazio Carbone, Brian C Gilger
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214214 (2019)
Morphological characterization and multi-locus DNA sequence analysis of fungal isolates obtained from 32 clinical cases of equine fungal keratitis (FK) was performed to identify species and determine associations with antifungal susceptibility, respo
Externí odkaz:
https://doaj.org/article/bd097471a90542d59a69d50ae340d697
Autor:
Jacob P. Nilles, Darby Roberts, Jacklyn H. Salmon, Liujiang Song, Carly O’Dea, Lindsay T. Marjoram, Jacquelyn J. Bower, Matthew L. Hirsch, Brian C. Gilger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 227-235 (2023)
Ocular graft versus host disease (OGvHD) develops after allogeneic hematopoietic stem cell transplantation (HSCT) and manifests as ocular surface inflammatory disease. This study evaluated the efficacy of adeno-associated virus (AAV) gene therapy enc
Externí odkaz:
https://doaj.org/article/c856cf60be50447ab1c43e9f6863c637
Publikováno v:
Journal of Fungi, Vol 9, Iss 10, p 966 (2023)
Fungal keratitis (FK) is an invasive infection of the cornea primarily associated with Aspergillus and Fusarium species. FK is treated empirically with a limited selection of topical antifungals with varying levels of success. Though clinical infecti
Externí odkaz:
https://doaj.org/article/71a3d395621a4e7ebe49f3481f1cdbac
Autor:
Liujiang Song, Jacquelyn J. Bower, Telmo Llanga, Jacklyn H. Salmon, Matthew L. Hirsch, Brian C. Gilger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 24-32 (2020)
The chronic ocular toxicity, tolerability, and inflammation following corneal intrastromal injection of saline or escalating doses of an adeno-associated virus (AAV) containing a codon-optimized α-l-iduronidase (AAV-opt-IDUA) expression cassette wer
Externí odkaz:
https://doaj.org/article/e2cdd5cfe5f34b9e86383fe2d4da7c9a
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-10 (2017)
Abstract Background We aimed to determine and compare the in vitro effects of autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) and mesenchymal stem cell supernatant (MSC-Sp) on the wound healing capacity of equine corneal fibroblasts u
Externí odkaz:
https://doaj.org/article/8d75107f327f465b939961f8e6119126
Autor:
Nasif Mahmood, Taylor Cook Suh, Kiran M. Ali, Eelya Sefat, Ummay Mowshome Jahan, Yihan Huang, Brian C. Gilger, Jessica M. Gluck
Publikováno v:
Stem Cell Reviews and Reports. 18:2817-2832
Deficiency and dysfunction of corneal cells leads to the blindness observed in corneal diseases such as limbal stem cell deficiency (LSCD) and bullous keratopathy. Regenerative cell therapies and engineered corneal tissue are promising treatments for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e27a10b4a997ff2e606990ba432301
https://doi.org/10.1007/s12015-022-10435-8
https://doi.org/10.1007/s12015-022-10435-8
Publikováno v:
Veterinary Ophthalmology. 25:412-418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27b43b1e865961b5d187e9c82ca3911e
https://doi.org/10.1111/vop.12997
https://doi.org/10.1111/vop.12997
Publikováno v:
Equine Ophthalmology. :441-498
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd3a68ef5c8ca8ea3e84b9f8fa79cb7e
https://doi.org/10.1002/9781119782285.ch6
https://doi.org/10.1002/9781119782285.ch6
Publikováno v:
J Ocul Pharmacol Ther
PURPOSE: To determine if inhibition of Myristoylated Alanine Rich C Kinase Substrate (MARCKS) protein, using novel MARCKS inhibitor peptides, will reduce the severity of endotoxin-induced uveitis (EIU) in rats. METHODS: EIU was induced in Lewis rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3018117f47e68c78016e697d176582d4
https://doi.org/10.1089/jop.2021.0114
https://doi.org/10.1089/jop.2021.0114