Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Brian C, Schaefer"'
Autor:
Evalyne N. Wambugu, Gathii Kimita, Sarah N. Kituyi, Michael A. Washington, Clement Masakhwe, Lucy M. Mutunga, Gurdeep Jaswant, S.M. Thumbi, Brian C. Schaefer, John N. Waitumbi
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 8, Pp 1642-1650 (2024)
Rabies, a viral disease that causes lethal encephalitis, kills ≈59,000 persons worldwide annually, despite availability of effective countermeasures. Rabies is endemic in Kenya and is mainly transmitted to humans through bites from rabid domestic d
Externí odkaz:
https://doaj.org/article/840e5c4ac1794f689dd3a21b40626d7a
Autor:
Kate E Mastraccio, Celeste Huaman, Si'Ana A Coggins, Caitlyn Clouse, Madeline Rader, Lianying Yan, Pratyusha Mandal, Imran Hussain, Anwar E Ahmed, Trung Ho, Austin Feasley, Bang K Vu, Ina L Smith, Wanda Markotter, Dawn L Weir, Eric D Laing, Christopher C Broder, Brian C Schaefer
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 10, Pp n/a-n/a (2023)
Abstract Infections with rabies virus (RABV) and related lyssaviruses are uniformly fatal once virus accesses the central nervous system (CNS) and causes disease signs. Current immunotherapies are thus focused on the early, pre‐symptomatic stage of
Externí odkaz:
https://doaj.org/article/f2f7561c73df4203a58b8d3978a4070c
Autor:
Celeste Huaman, Adrian C. Paskey, Caitlyn Clouse, Austin Feasley, Madeline Rader, Gregory K. Rice, Andrea E. Luquette, Maren C. Fitzpatrick, Hannah M. Drumm, Lianying Yan, Regina Z. Cer, Marina Donduashvili, Tamar Buchukuri, Anna Nanava, Christine E. Hulseberg, Michael A. Washington, Eric D. Laing, Francisco Malagon, Christopher C. Broder, Kimberly A. Bishop-Lilly, Brian C. Schaefer
Publikováno v:
Viruses, Vol 15, Iss 9, p 1797 (2023)
Rabies is a fatal zoonosis that is considered a re-emerging infectious disease. Although rabies remains endemic in canines throughout much of the world, vaccination programs have essentially eliminated dog rabies in the Americas and much of Europe. H
Externí odkaz:
https://doaj.org/article/b34376f25a66460d831389ae1c6da654
Autor:
Elisabet Bjanes, Reyna Garcia Sillas, Rina Matsuda, Benjamin Demarco, Timothée Fettrelet, Alexandra A DeLaney, Opher S Kornfeld, Bettina L Lee, Eric M Rodríguez López, Daniel Grubaugh, Meghan A Wynosky-Dolfi, Naomi H Philip, Elise Krespan, Dorothy Tovar, Leonel Joannas, Daniel P Beiting, Jorge Henao-Mejia, Brian C Schaefer, Kaiwen W Chen, Petr Broz, Igor E Brodsky
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009967 (2021)
Cell death plays a critical role in inflammatory responses. During pyroptosis, inflammatory caspases cleave Gasdermin D (GSDMD) to release an N-terminal fragment that generates plasma membrane pores that mediate cell lysis and IL-1 cytokine release.
Externí odkaz:
https://doaj.org/article/8d9976e5a9e54adc98393333ee0b5aa5
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 5, p e1007986 (2021)
The adaptive immune system serves as a potent and highly specific defense mechanism against pathogen infection. One component of this system, the effector T cell, facilitates pathogen clearance upon detection of specific antigens by the T cell recept
Externí odkaz:
https://doaj.org/article/410e6f8f72684783986f3c0b857dcfc2
Autor:
Kariana E. Rios, Ming Zhou, Nathaniel M. Lott, Chelsi R. Beauregard, Dennis P. McDaniel, Thomas P. Conrads, Brian C. Schaefer
Publikováno v:
Cells, Vol 11, Iss 7, p 1175 (2022)
CARD19 is a mitochondrial protein of unknown function. While CARD19 was originally reported to regulate TCR-dependent NF-κB activation via interaction with BCL10, this function is not recapitulated ex vivo in primary murine CD8+ T cells. Here, we em
Externí odkaz:
https://doaj.org/article/8f981d76c573421587c0da605ad086c0
Autor:
Brian C. Schaefer
Publikováno v:
Gene Cloning and Analysis ISBN: 9781003421474
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f5e663e5acfc8cb341ea915974c0bf
https://doi.org/10.1201/9781003421474-7
https://doi.org/10.1201/9781003421474-7
Autor:
Dawn L. Weir, Si’Ana A. Coggins, Bang K. Vu, Jessica Coertse, Lianying Yan, Ina L. Smith, Eric D. Laing, Wanda Markotter, Christopher C. Broder, Brian C. Schaefer
Publikováno v:
Viruses, Vol 13, Iss 3, p 391 (2021)
Australian bat lyssavirus (ABLV) is a rhabdovirus that circulates in four species of pteropid bats (ABLVp) and the yellow-bellied sheath-tailed bat (ABLVs) in mainland Australia. In the three confirmed human cases of ABLV, rabies illness preceded fat
Externí odkaz:
https://doaj.org/article/33cbc7344ca540ca93d5a6f8ca07b5c2
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2524
Bioluminescence imaging (BLI) is a technique that can be employed to quantify biological processes in living cells. When used in small animal models such as mice, BLI can provide both longitudinal and positional information regarding the biological p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::faaa2a3c578c48bce181a9a113f5a07e
https://pubmed.ncbi.nlm.nih.gov/35821488
https://pubmed.ncbi.nlm.nih.gov/35821488
Autor:
Eric D. Laing, Spencer L. Sterling, Dawn L. Weir, Chelsi R. Beauregard, Ina L. Smith, Sasha E. Larsen, Lin-Fa Wang, Andrew L. Snow, Brian C. Schaefer, Christopher C. Broder
Publikováno v:
Viruses, Vol 11, Iss 3, p 260 (2019)
Bats are increasingly implicated as hosts of highly pathogenic viruses. The underlying virus–host interactions and cellular mechanisms that promote co-existence remain ill-defined, but physiological traits such as flight and longevity are proposed
Externí odkaz:
https://doaj.org/article/24447aa6e3b64b23b8ec387e3a9ae465