Zobrazeno 1 - 10
of 278
pro vyhledávání: '"Brian C, Healy"'
Autor:
Evan Madill, Brian C. Healy, Negar Molazadeh, Mariann Polgar‐Turcsanyi, Bonnie I. Glanz, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 10, Pp 2719-2730 (2024)
Abstract Objective Glial fibrillary acidic protein (GFAP) is expressed in astrocytes and may be a useful marker of non‐active progressive multiple sclerosis (MS). We evaluate serum GFAP (sGFAP) in a large cohort of MS patients to determine if it pr
Externí odkaz:
https://doaj.org/article/966a08e2c53e4a22b825ebb28ba94705
Autor:
Alicia Gonzalez-Martinez, Gauruv Bose, Hrishikesh Lokhande, Shrishti Saxena, Brian C. Healy, Mariann Polgar-Turcsanyi, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-8 (2023)
Abstract Background Multiple sclerosis (MS) is a chronic demyelinating autoimmune disorder which may cause long-term disability. MicroRNA (miRNA) are stable, non-coding molecules that have been identified in our Comprehensive Longitudinal Investigati
Externí odkaz:
https://doaj.org/article/73a3adb279fc4ea89043543b396d0804
Autor:
Alicia Gonzalez-Martinez, Rohit Patel, Brian C. Healy, Hrishikesh Lokhande, Anu Paul, Shrishti Saxena, Mariann Polgar-Turcsanyi, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-8 (2023)
Abstract Background Multiple sclerosis (MS) is a disabling autoimmune demyelinating disorder affecting young people and causing significant disability. In the last decade, different microRNA (miRNA) expression patterns have been associated to several
Externí odkaz:
https://doaj.org/article/dc8a9c5060d94362ad72bda2d15d0d9a
Autor:
Rachel A. Millstein, Julia Golden, Brian C. Healy, Hermioni L. Amonoo, Lauren E. Harnedy, Alba Carrillo, Christopher M. Celano, Jeff C. Huffman
Publikováno v:
Health Psychology and Behavioral Medicine, Vol 10, Iss 1, Pp 713-730 (2022)
Background: Physical activity is critical for preventing and treating Type 2 diabetes (T2D). It is important to identify different profiles of physical activity change among those participating in behavioral interventions to optimize intervention-per
Externí odkaz:
https://doaj.org/article/2a0448632a5746afb1135df9b67fe5b9
Autor:
Neda Sattarnezhad, Brian C. Healy, Moogeh Baharnoori, Camilo Diaz-Cruz, James Stankiewicz, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
BMC Neurology, Vol 22, Iss 1, Pp 1-8 (2022)
Abstract Background To compare the effectiveness of dimethyl fumarate (DMF) with subcutaneous interferon beta-1a (IFNβ-1a) in controlling disease activity in patients with relapsing–remitting Multiple Sclerosis (MS). Methods Clinical and imaging d
Externí odkaz:
https://doaj.org/article/d7f3ee1685bf49ccb707649015e23369
Autor:
Tanuja Chitnis, Belinda J. Kaskow, Junning Case, Katherine Hanus, Zhenhua Li, Johnna F. Varghese, Brian C. Healy, Christian Gauthier, Taylor J. Saraceno, Shrishti Saxena, Hrishikesh Lokhande, Thais G. Moreira, Jonathan Zurawski, Rachel E. Roditi, Regan W. Bergmark, Federico Giovannoni, Maria F. Torti, Zhaorong Li, Francisco Quintana, William A. Clementi, Kunwar Shailubhai, Howard L. Weiner, Clare M. Baecher-Allan
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundParenteral anti-CD3 Mab (OKT3) has been used to treat transplant rejection and parental administration of a humanized anti-CD3 Mab (Teplizumab) showed positive effects in diabetes. Nasal administration of anti-CD3 Mab has not been carried o
Externí odkaz:
https://doaj.org/article/ee25d63832984d8fb1ef65c1fa2ffd07
Autor:
Emily H Feig, Lauren E Harnedy, Anne N Thorndike, Christina Psaros, Brian C Healy, Jeff C Huffman
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 10, p e39856 (2022)
BackgroundPhysical activity levels after bariatric surgery are usually low, despite the significant protective health benefits of physical activity in this population. Positive psychological well-being is associated with improved adherence to health
Externí odkaz:
https://doaj.org/article/595c7825541746cea951430eaea563c8
Autor:
Kristin Galetta, Chinmay Deshpande, Brian C. Healy, Bonnie Glanz, Marina Ziehn, Shrishti Saxena, Anu Paul, Fermisk Saleh, Mikaela Collins, Patricia Gaitan‐Walsh, Paola Castro‐Mendoza, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 3, Pp 631-638 (2021)
Abstract Objective Serum neurofilament light (sNfL) is a promising new biomarker in multiple sclerosis (MS). We explored the relationship between sNfL and health outcomes and resource use in MS patients. Methods MS patients with serum samples and hea
Externí odkaz:
https://doaj.org/article/4b7c25b42f854aa1a018f07ebfcd118e
Autor:
Mai Fujiwara, Radhika Raheja, Lucien P. Garo, Amrendra K. Ajay, Ryoko Kadowaki-Saga, Sukrut H. Karandikar, Galina Gabriely, Rajesh Krishnan, Vanessa Beynon, Anu Paul, Amee Patel, Shrishti Saxena, Dan Hu, Brian C. Healy, Tanuja Chitnis, Roopali Gandhi, Howard L. Weiner, Gopal Murugaiyan
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 10 (2022)
A disequilibrium between immunosuppressive Tregs and inflammatory IL-17–producing Th17 cells is a hallmark of autoimmune diseases, including multiple sclerosis (MS). However, the molecular mechanisms underlying the Treg and Th17 imbalance in CNS au
Externí odkaz:
https://doaj.org/article/f89dcb7cef1c42e89481250a5cdf5db1
Autor:
Mattia Rosso, Cindy T. Gonzalez, Brian C. Healy, Shrishti Saxena, Anu Paul, Kjetil Bjornevik, Jens Kuhle, Pascal Benkert, David Leppert, Charles Guttmann, Rohit Bakshi, Howard L. Weiner, Tanuja Chitnis
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 6, Pp 945-955 (2020)
Abstract Objective Multiple sclerosis (MS) is an autoimmune demyelinating disorder, which is characterized by relapses and remissions. Serum neurofilament light chain (sNfL) is an emerging biomarker of disease activity but its clinical use is still l
Externí odkaz:
https://doaj.org/article/803a62e77ea64fa5b7bb2923000a7e6e