Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Brian C, Gilger"'
Autor:
Jacob P. Nilles, Darby Roberts, Jacklyn H. Salmon, Liujiang Song, Carly O’Dea, Lindsay T. Marjoram, Jacquelyn J. Bower, Matthew L. Hirsch, Brian C. Gilger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 227-235 (2023)
Ocular graft versus host disease (OGvHD) develops after allogeneic hematopoietic stem cell transplantation (HSCT) and manifests as ocular surface inflammatory disease. This study evaluated the efficacy of adeno-associated virus (AAV) gene therapy enc
Externí odkaz:
https://doaj.org/article/c856cf60be50447ab1c43e9f6863c637
Publikováno v:
Journal of Fungi, Vol 9, Iss 10, p 966 (2023)
Fungal keratitis (FK) is an invasive infection of the cornea primarily associated with Aspergillus and Fusarium species. FK is treated empirically with a limited selection of topical antifungals with varying levels of success. Though clinical infecti
Externí odkaz:
https://doaj.org/article/71a3d395621a4e7ebe49f3481f1cdbac
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-9 (2021)
Abstract Background Superficial chronic corneal epithelial defects (SCCEDs) are spontaneous corneal defects in dogs that share many clinical and pathologic characteristics to recurrent corneal erosions (RCE) in humans. Boxer dogs are predisposed to S
Externí odkaz:
https://doaj.org/article/69d002e17865479dbcfc1f716fded2e8
Autor:
Liujiang Song, Jacquelyn J. Bower, Telmo Llanga, Jacklyn H. Salmon, Matthew L. Hirsch, Brian C. Gilger
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss , Pp 24-32 (2020)
The chronic ocular toxicity, tolerability, and inflammation following corneal intrastromal injection of saline or escalating doses of an adeno-associated virus (AAV) containing a codon-optimized α-l-iduronidase (AAV-opt-IDUA) expression cassette wer
Externí odkaz:
https://doaj.org/article/e2cdd5cfe5f34b9e86383fe2d4da7c9a
Autor:
Hiroki Tsujinaka, Jie Fu, Jikui Shen, Yun Yu, Zibran Hafiz, Joshua Kays, David McKenzie, Delia Cardona, David Culp, Ward Peterson, Brian C. Gilger, Christopher S. Crean, Jin-Zhong Zhang, Yogita Kanan, Weiling Yu, Jeffrey L. Cleland, Ming Yang, Justin Hanes, Peter A. Campochiaro
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Neovascular age-related macular degeneration and diabetic retinopathy are currently treated with repeated intravitreous injections of VEGF neutralizing proteins. Here the authors develop a microparticle-loaded tyrosine kinase inhibitor therapy, which
Externí odkaz:
https://doaj.org/article/2ec68ea8afa548e39d54ab7c4b1ff7de
Autor:
Elizabeth Crabtree, Katy Uribe, Sara M Smith, Darby Roberts, Jacklyn H Salmon, Jacquelyn J Bower, Liujiang Song, Prabhakar Bastola, Matthew L Hirsch, Brian C Gilger
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0270972 (2022)
Equine recurrent uveitis (ERU) is a spontaneous, painful, and vision threatening disease affecting up to 25% of equine populations worldwide. Current treatments of ERU are non-specific and have many side effects which limits them to short-term use. I
Externí odkaz:
https://doaj.org/article/09fa11cc71154043970cb391d0db4f03
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-10 (2017)
Abstract Background We aimed to determine and compare the in vitro effects of autologous bone marrow-derived mesenchymal stem cells (BM-MSCs) and mesenchymal stem cell supernatant (MSC-Sp) on the wound healing capacity of equine corneal fibroblasts u
Externí odkaz:
https://doaj.org/article/8d75107f327f465b939961f8e6119126
Autor:
Nasif Mahmood, Taylor Cook Suh, Kiran M. Ali, Eelya Sefat, Ummay Mowshome Jahan, Yihan Huang, Brian C. Gilger, Jessica M. Gluck
Publikováno v:
Stem Cell Reviews and Reports. 18:2817-2832
Deficiency and dysfunction of corneal cells leads to the blindness observed in corneal diseases such as limbal stem cell deficiency (LSCD) and bullous keratopathy. Regenerative cell therapies and engineered corneal tissue are promising treatments for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e27a10b4a997ff2e606990ba432301
https://doi.org/10.1007/s12015-022-10435-8
https://doi.org/10.1007/s12015-022-10435-8
Autor:
Megan Cullen, Megan E Jacob, Vicki Cornish, Ian Q VanderSchel, Henry Van T Cotter, Marc A Cubeta, Ignazio Carbone, Brian C Gilger
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214214 (2019)
Morphological characterization and multi-locus DNA sequence analysis of fungal isolates obtained from 32 clinical cases of equine fungal keratitis (FK) was performed to identify species and determine associations with antifungal susceptibility, respo
Externí odkaz:
https://doaj.org/article/bd097471a90542d59a69d50ae340d697
Autor:
Hannah L. Smith, Alix K. Berglund, James B. Robertson, Lauren V. Schnabel, Richard J. McMullen, Brian C. Gilger, Annie Oh
Publikováno v:
Veterinary Ophthalmology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::818c04f89f79603fc40ea1b304b0a741
https://doi.org/10.1111/vop.13098
https://doi.org/10.1111/vop.13098