Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Brian Buckley"'
Publikováno v:
Frontiers in Applied Mathematics and Statistics, Vol 10 (2024)
IntroductionBayesian approaches to patient phenotyping in clinical observational studies have been limited by the computational challenges associated with applying the Markov Chain Monte Carlo (MCMC) approach to real-world data. Approximate Bayesian
Externí odkaz:
https://doaj.org/article/c28465e534c04c5dbdaa50ee6be12f6a
Autor:
Florian Wittlinger, Blessing C. Ogboo, Ekaterina Shevchenko, Tahereh Damghani, Calvin D. Pham, Ilse K. Schaeffner, Brandon T. Oligny, Surbhi P. Chitnis, Tyler S. Beyett, Alexander Rasch, Brian Buckley, Daniel A. Urul, Tatiana Shaurova, Earl W. May, Erik M. Schaefer, Michael J. Eck, Pamela A. Hershberger, Antti Poso, Stefan A. Laufer, David E. Heppner
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Bivalent molecules consisting of groups connected through bridging linkers often exhibit strong target binding and unique biological effects. However, developing bivalent inhibitors with the desired activity is challenging due to the dual mo
Externí odkaz:
https://doaj.org/article/4d98b317db4743c79540cdb1697614f4
Autor:
Cathy Murphy, Mandy Fader, Donna Z. Bliss, Brian Buckley, Rowan Cockerell, Alan Cottenden, Jan Kottner, Joan Ostaszkiewicz
Publikováno v:
Continence, Vol 8, Iss , Pp 101049- (2023)
Aim:: To summarise the available evidence on the use of continence products to manage urinary or faecal incontinence published since the 6th International Consultation on Incontinence (2017) and provide key recommendations for the use of products in
Externí odkaz:
https://doaj.org/article/8e0b2686b6e1453f91a58e67a5b92a91
Autor:
Abigail Lazofsky, Anita Brinker, Ruby Gupta, Emily Barrett, Lauren M. Aleksunes, Zorimar Rivera-Núñez, Brian Buckley
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e16940- (2023)
Zearalenone and its metabolites, a group of endocrine disrupting mycotoxins, have been linked to adverse reproductive health effects. They cross the placental barrier, potentially reaching the fetus. In this study, we adapted and optimized our protoc
Externí odkaz:
https://doaj.org/article/860959ea07064e26a831be515840f5e1
Publikováno v:
Emerging Contaminants, Vol 8, Iss , Pp 318-328 (2022)
Quaternary ammonium compounds (QACs) are a class of antimicrobial disinfectants whose use in cleaning products increased during the COVID-19 pandemic. Chemically, their low vapor pressure indicates a proclivity to persist on surfaces, and their prese
Externí odkaz:
https://doaj.org/article/cff7a3a49fed483081a775e910902334
Autor:
Daniel Rizzolo, Bo Kong, Rulaiha E. Taylor, Anita Brinker, Michael Goedken, Brian Buckley, Grace L. Guo
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3847-3856 (2021)
Bile acids (BAs) are amphipathic molecules important for metabolism of cholesterol, absorption of lipids and lipid soluble vitamins, bile flow, and regulation of gut microbiome. There are over 30 different BA species known to exist in humans and mice
Externí odkaz:
https://doaj.org/article/0c440801a93b443080e61c7182e0677c
Autor:
Zorimar Rivera-Núñez, Megan Hansel, Camila Capurro, Danielle Kozlosky, Christina Wang, Cathleen L. Doherty, Brian Buckley, Pamela Ohman-Strickland, Richard K. Miller, Thomas G. O’Connor, Lauren M. Aleksunes, Emily S. Barrett
Publikováno v:
Toxics, Vol 11, Iss 7, p 589 (2023)
Cadmium exposure has been associated with adverse perinatal outcomes. One possible mechanism is endocrine disruption. Studies of non-pregnant adults suggest that cadmium impacts androgen production; here, we examined these associations during pregnan
Externí odkaz:
https://doaj.org/article/e1be5ec65e22499fa16865694e4f8927
Autor:
Chelsea M. Cary, Glen M. DeLoid, Zhenning Yang, Dimitrios Bitounis, Marianne Polunas, Michael J. Goedken, Brian Buckley, Byron Cheatham, Phoebe A. Stapleton, Philip Demokritou
Publikováno v:
Nanomaterials, Vol 13, Iss 4, p 720 (2023)
Recent studies in experimental animals found that oral exposure to micro- and nano-plastics (MNPs) during pregnancy had multiple adverse effects on outcomes and progeny, although no study has yet identified the translocation of ingested MNPs to the p
Externí odkaz:
https://doaj.org/article/c33eed4e9afc480ba6b4c39a8f5707ec
Autor:
Radosław Lewiński, Agnieszka Hernik, Monika Liszewska, Brian Buckley, Katarzyna Czaja, Wojciech Korcz, Anna Słomczyńska, Paweł Struciński
Publikováno v:
Molecules, Vol 28, Iss 2, p 842 (2023)
Honey is considered to be a health-promoting food product. Therefore, it is assumed that it should be free of contaminants. Although the use of organochlorine pesticides (OCPs) was banned a few decades ago in developed countries, persistent organic p
Externí odkaz:
https://doaj.org/article/c24a1ed4a9cb4a6d839658d4055e7e69
Autor:
Abigail Lazofsky, Brian Buckley
Publikováno v:
Molecules, Vol 27, Iss 24, p 8835 (2022)
Ingestion of water is a major route of human exposure to environmental contaminants. There have been numerous studies exploring the different compounds present in drinking water, with recent attention drawn to a new class of emerging contaminants: en
Externí odkaz:
https://doaj.org/article/4a9acdd14755486b985e8159f351b92c