Výsledky vyhledávání - "Brian Brissoni"

CARMA1 is a critical lipid raft–associated regulator of TCR-induced NF-κB activation

Autor: Claude Bron, Salvatore Valitutti, Daniel F. Legler, Brian Brissoni, David Bonnet, Olivier Gaide, Jürg Tschopp, Benoit Favier, Margot Thome

Publikováno v: Nature Immunology. 3:836-843

CARMA1 is a lymphocyte-specific member of the membrane-associated guanylate kinase (MAGUK) family of scaffolding proteins, which coordinate signaling pathways emanating from the plasma membrane. CARMA1 interacts with Bcl10 via its caspase-recruitment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::966bbe533f9ad633e13944078ebc2618
https://doi.org/10.1038/ni830

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Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

Autor: Jürg Tschopp, Natalia Olivos, Brian Brissoni, Rudi Beyaert, Sophie Janssens, Kimberly Burns

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 197, no. 2, pp. 263-8

Toll-like receptors (TLRs) and members of the proinflammatory interleukin 1 receptor (IL-1R) family are dependent on the presence of MyD88 for efficient signal transduction. The bipartite nature of MyD88 (N-terminal death domain [DD] and COOH-termina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892b88a42b1d95d3eb105ab3d6c2fd49
https://pubmed.ncbi.nlm.nih.gov/12538665

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