Zobrazeno 1 - 10
of 322
pro vyhledávání: '"Brian Bressler"'
Autor:
Susanna Meade, Jeremy Liu Chen Kiow, Cristian Massaro, Gurpreet Kaur, Elizabeth Squirell, Brian Bressler, Genelle Lunken
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTLoss of response to therapy in inflammatory bowel disease (IBD) has led to a surge in research focusing on precision medicine. Three systematic reviews have been published investigating the associations between gut microbiota and disease acti
Externí odkaz:
https://doaj.org/article/fdb2052ff4984c238bed211c7a10682a
Autor:
Brian Bressler
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 16 (2023)
Over the past two decades, 11 biologic agents have been approved for use in most countries for the treatment of moderate-to-severe inflammatory bowel disease (IBD). Antitumor necrosis factor α (anti-TNF) agents are commonly used as the first biologi
Externí odkaz:
https://doaj.org/article/b9bc10fd1e9b4c10ac3a062b7a3ca792
Autor:
Joannie M. Allaire, Anita Poon, Shauna M. Crowley, Xiao Han, Zohreh Sharafian, Navjit Moore, Martin Stahl, Brian Bressler, Pascal M. Lavoie, Kevan Jacobson, Xiaoxia Li, Bruce A. Vallance
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Intestinal epithelial cells (IEC) reside in close proximity to the gut microbiota and are hypo-responsive to bacterial products, likely to prevent maladaptive inflammatory responses. This is in part due to their strong expression of Single I
Externí odkaz:
https://doaj.org/article/15d2427d54394e72ab94d917fb2ea064
Autor:
Laura Cook, Daniel J. Lisko, May Q. Wong, Rosa V. Garcia, Megan E. Himmel, Ernest G. Seidman, Brian Bressler, Megan K. Levings, Theodore S. Steiner
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 485-506 (2020)
Background & Aims: Bacterial flagellin is an important antigen in inflammatory bowel disease, but the role of flagellin-specific CD4+ T cells in disease pathogenesis remains unclear. Also unknown is how changes in intestinal microbiome intersect with
Externí odkaz:
https://doaj.org/article/63c7574960da43a49aefc4bb623932ef
Autor:
Simon Sutcliffe, Shirin Kalyan, Jim Pankovich, Jenny M. H. Chen, Rashieda Gluck, Darby Thompson, Momir Bosiljcic, Mark Bazett, Richard N. Fedorak, Remo Panaccione, Jeffrey Axler, John K. Marshall, David W. Mullins, Boyko Kabakchiev, Dermot P. B. McGovern, Julie Jang, Andrew Coldman, Gillian Vandermeirsch, Brian Bressler, Hal Gunn
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Background: Current Crohn's disease (CD) therapies focus on suppressing immune function and come with consequent risk, such as infection and cancer. Notwithstanding, most CD patients still experience disease progression. There is a need for new CD tr
Externí odkaz:
https://doaj.org/article/16ebca018dc54a3db4c12643872ffe03
Autor:
Ho Pan Sham, Mark Bazett, Momir Bosiljcic, Hyungjun Yang, Beryl Luk, Hong T. Law, Vijay Morampudi, Hong B. Yu, Jim Pankovich, Simon Sutcliffe, Brian Bressler, John K. Marshall, Richard N. Fedorak, Jenny Chen, Michelle Jones, Hal Gunn, Shirin Kalyan, Bruce A. Vallance
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Current ulcerative colitis (UC) treatments are focused on symptom management primarily via immune suppression. Despite the current arsenal of immunosuppressant treatments, the majority of patients with UC still experience disease progress
Externí odkaz:
https://doaj.org/article/60605729c3b44b1cbbdab2ced5054902
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 29, Iss 7, Pp 369-372 (2015)
BACKGROUND: Objective monitoring of the severity of inflammation in patients with inflammatory bowel disease (IBD) is an essential part of disease management. However, repeat endoscopy to define extent and severity of inflammation is not practical. F
Externí odkaz:
https://doaj.org/article/b24956e1d1154bf196d744d7f311e985
Autor:
Glynis Byrne, Greg Rosenfeld, Yvette Leung, Hong Qian, Julia Raudzus, Carlos Nunez, Brian Bressler
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2017 (2017)
Background. Inflammatory bowel disease (IBD) patients are not routinely screened for depression and anxiety despite knowledge of an increased prevalence in people with chronic disease and negative effects on quality of life. Methods. Prevalence of an
Externí odkaz:
https://doaj.org/article/ffc03e04a5064200a694ea6aef14a667
Autor:
Yvonne Tse, David Armstrong, Christopher N. Andrews, Alain Bitton, Brian Bressler, John Marshall, Louis W. C. Liu
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2017 (2017)
Background. Chronic idiopathic constipation (CIC) and constipation-predominant irritable bowel syndrome (IBS-C) are common functional lower gastrointestinal disorders that impair patients’ quality of life. In a national survey, we aimed to evaluate
Externí odkaz:
https://doaj.org/article/42bfe82d6f0f48d4aad9a17781f75bbd
Autor:
Alan Hoi Lun Yau, George Ou, Cherry Galorport, Jack Amar, Brian Bressler, Fergal Donnellan, Hin Hin Ko, Eric Lam, Robert Allan Enns
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 28, Iss 2, Pp 72-76 (2014)
BACKGROUND: Hemospray (Cook Medical, USA) has recently been approved in Canada for the management of nonvariceal upper gastrointestional bleeding (UGIB).
Externí odkaz:
https://doaj.org/article/7eafbde55e4a473384a0eee427c53580