Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Brian Bonish"'
Autor:
Stephen Wood, Vijayakumar Jayaraman, Erica J Huelsmann, Brian Bonish, Derick Burgad, Gayathri Sivaramakrishnan, Shanshan Qin, Luisa A DiPietro, Andrew Zloza, Chunxiang Zhang, Sasha H Shafikhani
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91574 (2014)
Prior studies suggest that the impaired healing seen in diabetic wounds derives from a state of persistent hyper-inflammation characterized by harmful increases in inflammatory leukocytes including macrophages. However, such studies have focused on w
Externí odkaz:
https://doaj.org/article/8b4305a4763a4a0fa7518fdc1bf50a85
Autor:
Kenneth B. Gordon, Brian Bonish, Deborah J. Marble, Kellean A. Schriedel, Brian J. Nickoloff, Mark W. Lingen, Luisa A. DiPietro
Publikováno v:
Journal of Investigative Dermatology Symposium Proceedings. 11:16-29
Following injury, skin establishes a balance between too little inflammation increasing risk of infection, and excessive inflammation contributing to delayed wound healing and scarring. Mounting evidence indicates both initiation and termination of i
Autor:
Manuel O. Diaz, Patricia Bacon, Kimberly E. Foreman, Jian Zhong Qin, Brian Bonish, Brian J. Nickoloff, June K. Robinson, Mitchell F. Denning, Vijaya Chaturvedi
Publikováno v:
Experimental Dermatology. 12:255-260
It has been established that Id proteins can block the basic helix-loop-helix (HLH) transcription factors, thereby impacting the onset of senescence in keratinocytes, as well as influencing tumorigenesis involving squamous cell carcinomas. However, t
Publikováno v:
Experimental Dermatology. 11:573-583
Properly regulated keratinocyte cell death is fundamentally important to maintain structural integrity and homeostatic function of epidermis. Moreover, from an oncological perspective, therapeutic approaches selectively targeting apoptosis of maligna
Autor:
Lucio Miele, Vijaya Chaturvedi, Mitchell F. Denning, J-Z Qin, Brian J. Nickoloff, Brian Bonish
Publikováno v:
Cell Death & Differentiation. 9:842-855
Establishing an effective epidermal barrier requires a series of coordinated molecular events involving keratinocytes (KCs) within a stratified epithelium. Epidermal maturation depends on convergence of pathways involving components of NF-kappaB and
Publikováno v:
Journal of Dermatological Science. 24:212-225
T cells bearing natural killer receptors (NKRs) such as CD94 and CD161 are present in psoriasis. These immunocytes express several receptors for both classical and non-classical class I MHC molecules. Whether T cells bearing NKRs in psoriatic lesions
Autor:
Steven A. Porcelli, Denis Jullien, Robert L. Modlin, Franca M. Spada, Brian Bonish, Yves Dutronc, Brian J. Nickoloff, Barbara Bei Huang
Publikováno v:
The Journal of Immunology. 165:4076-4085
The MHC class I-like protein CD1d is a nonpolymorphic molecule that plays a central role in development and activation of a subset of T cells that coexpress receptors used by NK cells (NK-T cells). Recently, T cells bearing NK receptors were identifi
Autor:
Susan M. Eddy, Ara A. Vaporciyan, Kent J. Johnson, Michael L. Jones, Peter A. Ward, Kimberly E. Foreman, M. Michael Glovsky, Brian Bonish
Publikováno v:
Journal of Clinical Investigation. 94:1147-1155
Human umbilical vein endothelial cells have recently been shown to respond to C5a with increases in intracellular Ca2+, production of D-myo-inositol 1,4,5-triphosphate and superoxide anion generation. In the current studies, C5a had been found to cau
Publikováno v:
Journal of drugs in dermatology : JDD. 5(9)
Acrodermatitis continua of Hallopeau (ACH) is a rare disease. Little is known about its etiology or relative effectiveness of the various therapeutic approaches. However, in the literature a pattern seems to be developing on successfully treated pati
Publikováno v:
The British journal of dermatology. 153(5)
Summary Background The pathophysiology of psoriasis is poorly understood, and the mechanism of action of biological agents interfering with tumour necrosis factor (TNF)-α that improve psoriatic plaques is completely unknown. Objectives To begin to u