Výsledky vyhledávání - "Brian Bodemann"

Akademický článek

Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells.

Autor: Anand K Ganesan, Hsiang Ho, Brian Bodemann, Sean Petersen, Jayavani Aruri, Shiney Koshy, Zachary Richardson, Lu Q Le, Tatiana Krasieva, Michael G Roth, Pat Farmer, Michael A White

Publikováno v: PLoS Genetics, Vol 4, Iss 12, p e1000298 (2008)

Melanin protects the skin and eyes from the harmful effects of UV irradiation, protects neural cells from toxic insults, and is required for sound conduction in the inner ear. Aberrant regulation of melanogenesis underlies skin disorders (melasma and

Externí odkaz: https://doaj.org/article/6e8cb1d7e6c9434d943c7b29e3b17084

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Harnessing Functional Genomics to Reverse Chemoresistance in Breast Cancer

Autor: Brian Bodemann

Targeted therapy has proven to be an effective strategy in the treatment of breast cancer. An example of successful targeted therapy is trastuzumab, a humanized monoclonal antibody that binds to the extracellular domain of HER2, a receptor which is o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4b4bbfdd45f9ac8aba07816443d04c
https://doi.org/10.21236/ada484470

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