Zobrazeno 1 - 10 of 102 pro vyhledávání: '"Brian Barber"'
1
Akademický článek
Humanization of Pan-HLA-DR mAb 44H10 Hinges on Critical Residues in the Antibody Framework
Autor: Audrey Kassardjian, Danton Ivanochko, Brian Barber, Arif Jetha, Jean-Philippe Julien
Publikováno v: Antibodies, Vol 13, Iss 3, p 57 (2024)
Reducing the immunogenicity of animal-derived monoclonal antibodies (mAbs) for use in humans is critical to maximize therapeutic effectiveness and preclude potential adverse events. While traditional humanization methods have primarily focused on gra
Externí odkaz: https://doaj.org/article/f9f377da9ca54f4e8b648ec54573ffd2
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2
Akademický článek
Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses
Autor: Audrey Kassardjian, Eric Sun, Jamie Sookhoo, Krithika Muthuraman, Kayluz Frias Boligan, Iga Kucharska, Edurne Rujas, Arif Jetha, Donald R. Branch, Shawn Babiuk, Brian Barber, Jean-Philippe Julien
Publikováno v: Cell Reports, Vol 42, Iss 4, Pp 112391- (2023)
Summary: Subunit vaccines typically require co-administration with an adjuvant to elicit protective immunity, adding development hurdles that can impede rapid pandemic responses. To circumvent the need for adjuvant in a severe acute respiratory syndr
Externí odkaz: https://doaj.org/article/281ea69d22824c1bb136266379c38f62
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3
Akademický článek
Lipoprotein‐Like Nanoparticle Carrying Small Interfering RNA Against Spalt‐Like Transcription Factor 4 Effectively Targets Hepatocellular Carcinoma Cells and Decreases Tumor Burden
Autor: William Cruz, Huang Huang, Brian Barber, Elisa Pasini, Lili Ding, Gang Zheng, Juan Chen, Mamatha Bhat
Publikováno v: Hepatology Communications, Vol 4, Iss 5, Pp 769-782 (2020)
Patients with advanced hepatocellular carcinoma (HCC) are often unable to tolerate chemotherapy due to liver dysfunction in the setting of cirrhosis. We investigate high‐density lipoprotein (HDL)‐mimicking peptide phospholipid scaffold (HPPS), wh
Externí odkaz: https://doaj.org/article/6a5a5f4f41904d73b777e4a7b53cb122
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4
Akademický článek
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5
Elektronická kniha
How to Cheat at Designing a Windows Server 2003 Active Directory Infrastructure
Autor: Melissa M. Meyer, Michael Cross, Hal Kurz, Brian Barber
Windows 2003 Server is unquestionably the dominant enterprise level operating system in the industry, with 95% of all companies running it. And for the last tow years, over 50% of all product upgrades have been security related. Securing Windows Serv
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9
The Wirrall Family: Doncaster Merchants, Yorkshire Gentry, and Settlers in Ulster, 1514–1641
Autor: Brian Barber
Publikováno v: Yorkshire Archaeological Journal. 92:98-114
The Wirrall family emerged as leading figures in the borough of Doncaster in the early sixteenth century and by mid-century had begun to establish themselves firmly amongst the gentry. From time to...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bc864985cc2f027479f113e7101748df
https://doi.org/10.1080/00844276.2020.1803610
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10
Working in ‘The Cause of Bibliomania Throughout the World’: Sir Thomas Brooke (1830–1908), a Yorkshire Businessman-Bibliophile
Autor: Brian Barber
Publikováno v: Yorkshire Archaeological Journal. 90:158-177
Sir Thomas Brooke (1830–1908), a Huddersfield woollen cloth manufacturer and company director, was a major collector of books and manuscripts. His library, valued at his death at over £25,000, was one of the more notable of Victorian Britain. This
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce4d7e9e640d7fcba0c9f0ca49bf2038
https://doi.org/10.1080/00844276.2018.1465684
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