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of 6
pro vyhledávání: '"Brian A.B. Martin"'
Publikováno v:
Journal of Medical Virology. 84:912-922
A mutant of murine cytomegalovirus (MCMV), tsm5, which is temperature-sensitive for replication in murine embryo fibroblasts at 40°C, failed to replicate to detectable levels in mice. A total of 18 non-synonymous mutations have been identified in ts
Publikováno v:
Journal of Medical Virology
Identification of mutations in mutants derived chemically is a difficult and relatively random process. NimbleGen Comparative Genome Sequencing (CGS) was assessed as an inexpensive, rapid method of identifying mutations in the temperature‐sensitive
Autor:
Brian A.B. Martin, Elizabeth A. Dragon, David A. Rand, Paul McMaster, Howard Tang, Katharina O'Donnell, Scott L. Barmat, Elwyn Elias, Patricia A. Cane, Elizabeth H. Boxall, Jean Shaw, Sandy Buchan, Monz Ahmed, Nigel J. Burroughs, Karen Gutekunst, Deenan Pillay, David Mutimer
Publikováno v:
Journal of Hepatology. 30:715-721
Background/Aims: Orthotopic liver transplantation has an established role for the treatment of patients with chronic liver failure secondary to hepatitis B virus (HBV)infection. Unfortunately, recurrent infection of the graft can be associated with a
Autor:
Chukwudum P. Ilobi, Brian A.B. Martin
Publikováno v:
Journal of Virological Methods. 23:137-148
A plaque assay procedure has been adapted for VZV which, by obviating the need of a preformed cell monolayer, shortens the assay time, and provides improved sensitivity. The size and clarity of the plaques obtained are comparable to those seen in pre
Autor:
Christoph Jungwirth, Brian A.B. Martin, Peter H. Hofschneider, Hans Kroath, Gerd Wengler, Gehard Bodo
Publikováno v:
Pathobiology. 48:31-44
In primary chick embryo cells aged in vitro, vaccinia virus replication is drastically inhibited by pretreatment with low doses of interferon. The antiviral state was established with doses about ten times smaller than those required with normal prim
Publikováno v:
Virology. (1):114-122
Twenty-six non-synonymous and synonymous mutations have been identified in the temperature-sensitive (ts) mutant (tsm5) of the K181 (Birmingham) variant of murine cytomegalovirus that is deficient in DNA synthesis, processing and packaging at the non