Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Brian A. Pryce"'
Autor:
Guak-Kim Tan, Brian A Pryce, Anna Stabio, John V Brigande, ChaoJie Wang, Zheng Xia, Sara F Tufa, Douglas R Keene, Ronen Schweitzer
Publikováno v:
eLife, Vol 9 (2020)
Studies of cell fate focus on specification, but little is known about maintenance of the differentiated state. In this study, we find that the mouse tendon cell fate requires continuous maintenance in vivo and identify an essential role for TGFβ si
Externí odkaz:
https://doaj.org/article/08b49814dff4413798a4ba6fddbb0ae8
Publikováno v:
Stem Cell Reports
Summary Understanding cell recruitment in damaged tendons is critical for improvements in regenerative therapy. We recently reported that targeted disruption of transforming growth factor beta (TGFβ) type II receptor in the tendon cell lineage (Tgfb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f453f6bdeeab848ab04187133375f29c
http://europepmc.org/articles/PMC8693658
http://europepmc.org/articles/PMC8693658
Understanding the role of cell recruitment in tendon disorders is critical for improvements in regenerative therapy. We recently reported that targeted disruption of TGFβ type II receptor in the tendon cell lineage (Tgfbr2ScxCre) resulted in tenocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c3b851b57083f98a4aeb6f28e3410db
https://doi.org/10.1101/2020.11.11.378505
https://doi.org/10.1101/2020.11.11.378505
Autor:
Saundra Y. Schlesinger, Alice H. Huang, Ronen Schweitzer, Brian A. Pryce, Sara F. Tufa, Seongkyung Seo, Douglas R. Keene
Publikováno v:
Developmental biology. 470
Growth of the musculoskeletal system requires precise coordination between bone, muscle, and tendon during development. Insufficient elongation of the muscle-tendon unit relative to bone growth results in joint contracture, a condition characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2488f20d5f9e4dd77db152275d50f4c2
https://pubmed.ncbi.nlm.nih.gov/33248111
https://pubmed.ncbi.nlm.nih.gov/33248111
Autor:
Sigmar Stricker, Andreas Schedl, Betty Féret, Katherine Exelby, Fabio Da Silva, Pedro Vallecillo Garcia, Ronen Schweitzer, James Briscoe, Norbert B. Ghyselinck, Jozef Kaiser, Shahragim Tajbakhsh, Leif Carlsson, Pascal Dollé, Brian A. Pryce, Tomáš Zikmund, Marketa Tesarova, Glenda Comai, Muriel Rhinn, François Spitz, Valérie Dupé
Coordinated development of muscles, tendons, and their attachment sites ensures emergence of functional musculoskeletal units that are adapted to diverse anatomical demands among different species. How these different tissues are patterned and functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c9458b7a66545d9fe640680f204627
Autor:
Ronen Schweitzer, Chaojie Wang, John V. Brigande, Zheng Xia, Douglas R. Keene, Sara F. Tufa, Guak-Kim Tan, Brian A. Pryce, Anna Stabio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0d0aa0bfd6f0ccbe26d73103e007d1c
https://doi.org/10.7554/elife.52695.sa2
https://doi.org/10.7554/elife.52695.sa2
Publikováno v:
Connective Tissue Research. 59:295-308
Tendon injuries are clinically challenging due to poor healing. A better understanding of the molecular events that regulate tendon differentiation would improve current strategies for repair. The mouse model system has been instrumental to tendon st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986a053bdbeecaeb95021d04ac1ad982
https://doi.org/10.1080/03008207.2017.1383403
https://doi.org/10.1080/03008207.2017.1383403
Autor:
Ronen Schweitzer, John V. Brigande, Chaojie Wang, Zheng Xia, Sara F. Tufa, Guak-Kim Tan, Douglas R. Keene, Anna Stabio, Brian A. Pryce
Studies of cell fate focus on specification, but little is known about maintenance of the differentiated state. We find that TGFβ signaling plays an essential role in maintenance of the tendon cell fate. To examine the role TGFβ signaling in tenocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cc72d8c4a08a37ab5bf0531332c7a4
https://doi.org/10.1101/823021
https://doi.org/10.1101/823021
Autor:
John V. Brigande, Zheng Xia, Guak Kim Tan, Anna Stabio, Brian A. Pryce, Sara F. Tufa, Douglas R. Keene, Ronen Schweitzer, Chaojie Wang
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Studies of cell fate focus on specification, but little is known about maintenance of the differentiated state. In this study, we find that the mouse tendon cell fate requires continuous maintenance in vivo and identify an essential role for TGFβ si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6757b1a996dfb6bb1c09aee278fe609d
https://pubmed.ncbi.nlm.nih.gov/31961320
https://pubmed.ncbi.nlm.nih.gov/31961320
Autor:
Deepanwita Pal, Ronen Schweitzer, Sharon Krief, Neta Felsenthal, Elazar Zelzer, Brian A. Pryce, Sarah Rubin, Tomer Stern
Publikováno v:
Development.
Tendon-bone attachment sites, called entheses, are essential for musculoskeletal function. They are formed embryonically by Sox9+ progenitors and continue to develop postnatally utilizing Gli1 lineage cells. Despite their importance, we lack informat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e382d430227d852bd1ed128f6986fe5
https://doi.org/10.1242/dev.165381
https://doi.org/10.1242/dev.165381