Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brian A. Pink"'
Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humans.
Autor:
Henrik Zetterberg, Erik Mörtberg, Linan Song, Lei Chang, Gail K Provuncher, Purvish P Patel, Evan Ferrell, David R Fournier, Cheuk W Kan, Todd G Campbell, Ray Meyer, Andrew J Rivnak, Brian A Pink, Kaitlin A Minnehan, Tomasz Piech, David M Rissin, David C Duffy, Sten Rubertsson, David H Wilson, Kaj Blennow
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28263 (2011)
Amyloid β (Aβ) peptides are proteolytic products from amyloid precursor protein (APP) and are thought to play a role in Alzheimer disease (AD) pathogenesis. While much is known about molecular mechanisms underlying cerebral Aβ accumulation in fami
Externí odkaz:
https://doaj.org/article/bd279e68e5df447f8caafa35e86ed2e2
Autor:
Cheuk W. Kan, David C. Duffy, David M. Rissin, Todd G. Campbell, Derek R. DuPont, Andrew J. Rivnak, Carlos Cabrera, David Fournier, Sean Sullivan, Melissa Gardel, Brian A. Pink, Matthew W. Fishburn, Tomasz Piech, Linan Song
Publikováno v:
Journal of Immunological Methods. 424:20-27
We report a system and assay for performing fully-automated measurement of 6 proteins simultaneously with single molecule sensitivity. The system combines handling of samples, reagents, and consumables, with a module for imaging single molecule array
Autor:
Dandan Shan, Linan Song, Ryan B. Hayman, Sean Sullivan, Brian A. Pink, Melissa Gardel, Lyndsey York, David C. Duffy, Kaitlin A. Minnehan, Mingwei Zhao, Aaron F. Phillips, David R. Walt
Publikováno v:
Analytical Chemistry. 85:1932-1939
We report a method for the sensitive measurement of genomic DNA based on the direct detection of single molecules of DNA in arrays of femtoliter wells. The method begins by generating short fragments of DNA from large, double-stranded molecules of ge
Autor:
David H. Wilson, Purvish P. Patel, Linan Song, Andrew J. Rivnak, Brian A. Pink, Mary A. Till, Lei Chang, Cheuk W. Kan, David C. Duffy, Gail K. Provuncher, David Hanlon, Kaitlin A. Minnehan, David Fournier, William A. Faubion, Evan P. Ferrell, Todd G. Campbell
Publikováno v:
Journal of Immunological Methods. 372:177-186
The quantitative measurement of inflammatory cytokines in blood has been limited by insufficient sensitivity of conventional immunoassays. This limitation has prevented the widespread clinical monitoring of cytokine concentrations in chronic inflamma
Autor:
Cheuk W. Kan, Brian A. Pink, David H. Wilson, Purvish P. Patel, David C. Duffy, David M. Rissin, Linan Song, David Fournier, Evan P. Ferrell, Andrew J. Rivnak, Tomasz Piech, Gail K. Provuncher, Stuart C. Howes, Lei Chang, Kaitlin A. Minnehan, Todd G. Campbell
Publikováno v:
Analytical Chemistry. 83:2279-2285
We report a method for combining the detection of single molecules (digital) and an ensemble of molecules (analog) that is capable of detecting enzyme label from 10(-19) M to 10(-13) M, for use in high sensitivity enzyme-linked immunosorbent assays (
Autor:
Kaitlin A. Minnehan, Cheuk W. Kan, Brian A. Pink, David Hanlon, David Fournier, David C. Duffy, David H. Wilson, Lei Chang, Purvish P. Patel, Linan Song, Evan P. Ferrell
Publikováno v:
Journal of virological methods. 188(1-2)
Nucleic acid amplification techniques have become the mainstay for ultimate sensitivity for detecting low levels of virus, including human immunodeficiency virus (HIV). As a sophisticated technology with relative expensive reagents and instrumentatio
Autor:
Kaj Blennow, Brian A. Pink, Erik Mörtberg, David Fournier, Sten Rubertsson, Gail K. Provuncher, Lei Chang, Ray E. Meyer, Andrew J. Rivnak, David H. Wilson, Purvish P. Patel, Evan P. Ferrell, David M. Rissin, Henrik Zetterberg, Linan Song, Todd G. Campbell, Kaitlin A. Minnehan, Cheuk W. Kan, David C. Duffy, Tomasz Piech
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28263 (2011)
PLoS ONE
PLoS ONE
Amyloid β (Aβ) peptides are proteolytic products from amyloid precursor protein (APP) and are thought to play a role in Alzheimer disease (AD) pathogenesis. While much is known about molecular mechanisms underlying cerebral Aβ accumulation in fami