Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Brian A. Kudlow"'
Autor:
Leonardo A. Meza-Zepeda, Ola Myklebost, Brian A. Kudlow, Else Munthe, Eva W. Stratford, Bodil Bjerkehagen, Susanne Lorenz, Tale Barøy, Skyler J. Mishkin, Kjetil Boye, Heidi M. Namløs
Supplementary Table 1. A detailed overview of the somatic KIT and PDGFRA mutations found in the tumour, and somatic mutations found in plasma of the 50 GIST patients; Supplementary Table 2. Overview of mutated allele frequencies of the somatic mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de094658e299eebbe01656ca2dc4469
https://doi.org/10.1158/1535-7163.22504626.v1
https://doi.org/10.1158/1535-7163.22504626.v1
Autor:
Leonardo A. Meza-Zepeda, Ola Myklebost, Brian A. Kudlow, Else Munthe, Eva W. Stratford, Bodil Bjerkehagen, Susanne Lorenz, Tale Barøy, Skyler J. Mishkin, Kjetil Boye, Heidi M. Namløs
Supplementary Figure 1. Radiological evaluation of response to treatment. Supplementary Figure 2. Histological grouping of FFPE sections according to normal tissue.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6717f273a98b9f4196738e633597be3b
https://doi.org/10.1158/1535-7163.22504629.v1
https://doi.org/10.1158/1535-7163.22504629.v1
Autor:
Leonardo A. Meza-Zepeda, Ola Myklebost, Brian A. Kudlow, Else Munthe, Eva W. Stratford, Bodil Bjerkehagen, Susanne Lorenz, Tale Barøy, Skyler J. Mishkin, Kjetil Boye, Heidi M. Namløs
Molecular analysis of circulating tumor DNA (ctDNA) has a large potential for clinical application by capturing tumor-specific aberrations through noninvasive sampling. In gastrointestinal stromal tumor (GIST), analysis of KIT and PDGFRA mutations is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a61ea34cc16b4c9d9db089d4d01abfa
https://doi.org/10.1158/1535-7163.c.6537810.v1
https://doi.org/10.1158/1535-7163.c.6537810.v1
Autor:
Zane Jaafar, Josh Haimes, Thomas Harrison, Lindsay Peterkin, Martin Ranik, Kristin Scott, Brian A. Kudlow
Publikováno v:
Cancer Research. 82:2288-2288
After a decade of NGS technology and workflow innovation, personalized medicine is starting to become a reality. DNA fragmentation is still a critical bottleneck during library preparation. Sonication methods have been the gold standard for consisten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf46cb4b8f5d4c89841fe0cb7e5389a2
https://doi.org/10.1158/1538-7445.am2022-2288
https://doi.org/10.1158/1538-7445.am2022-2288
Publikováno v:
PLoS Genetics, Vol 9, Iss 6, p e1003592 (2013)
Identifying the physiological functions of microRNAs (miRNAs) is often challenging because miRNAs commonly impact gene expression under specific physiological conditions through complex miRNA::mRNA interaction networks and in coordination with other
Externí odkaz:
https://doaj.org/article/053f90eb3fb74ddd870810b0a077252a
Autor:
W. Glenn McCluggage, Eleanor Koay, Brian A. Kudlow, Jen-Chieh Lee, Tony Ng, Josh Haimes, Cheng-Han Lee, Colin J.R. Stewart, Bo Meng, Brady P. Culver, Ann Whitehouse, Nichola Cope
Publikováno v:
American Journal of Surgical Pathology. 41:773-780
Inflammatory myofibroblastic tumor (IMT) can occur in a number of anatomic sites, including the uterus. Like its soft tissue counterpart, uterine IMT frequently expresses ALK and harbors ALK genetic rearrangements. The aim of this study is to fully c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dcfaf8a19f803bc2c29afb1003b2bd7
https://doi.org/10.1097/pas.0000000000000801
https://doi.org/10.1097/pas.0000000000000801
Publikováno v:
Molecular Cell. 46:530-541
Gene regulation by microRNAs (miRNAs) under specific physiological conditions often involves complex interactions between multiple miRNAs and a large number of their targets, as well as coordination with other regulatory mechanisms, limiting the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b13b4d3a76fa02ed40208bfc972bbcc5
https://doi.org/10.1016/j.molcel.2012.03.011
https://doi.org/10.1016/j.molcel.2012.03.011
Autor:
Josh D. Haimes, Thomas D. Harrison, Namitha M. Nair, Jennifer Sims, Ian McKittrick, Laura M. Griffin, Laura Johnson, Brian A. Kudlow
Publikováno v:
The Journal of Immunology. 200:120.30-120.30
Introduction NGS-based analysis of the immune repertoire (IR) is a powerful tool to monitor disease, adaptive immune responses to disease, vaccination and therapeutic interventions. IR characterization by NGS usually requires large primer panels, due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbf1f14badbc11b2781e6ad4dad6d2d0
https://doi.org/10.4049/jimmunol.200.supp.120.30
https://doi.org/10.4049/jimmunol.200.supp.120.30
Autor:
Christopher R. Burtner, Brian A. Kudlow, Brian K. Kennedy, Elijah D. Johnston, Monique N. Stanfel
Publikováno v:
Molecular Biology of the Cell. 19:5238-5248
Hutchinson-Gilford progeria syndrome (HGPS) is a rare, debilitating disease with early mortality and rapid onset of aging-associated pathologies. It is linked to mutations in LMNA, which encodes A-type nuclear lamins. The most frequent HGPS-associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361f1fbe5178217e247dff4efcdfd2f1
https://doi.org/10.1091/mbc.e08-05-0492
https://doi.org/10.1091/mbc.e08-05-0492
Publikováno v:
Nature Reviews Molecular Cell Biology. 8:394-404
Progeroid syndromes have been the focus of intense research in part because they might provide a window into the pathology of normal ageing. Werner syndrome and Hutchinson-Gilford progeria syndrome are two of the best characterized human progeroid di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d24505a7313dbf36a52459bd35d1fe8e
https://doi.org/10.1038/nrm2161
https://doi.org/10.1038/nrm2161