Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Brian A. Horger"'
Publikováno v:
Journal of Neurochemistry. 66:1959-1962
Systemic administration of the anxiogenic benzodiazepine inverse agonist FG 7142 has been shown to increase selectively dopamine utilization in the medial prefrontal cortex and the shell, but not core, subregion of the nucleus accumbens. In the prese
Autor:
Jane R. Taylor, Brian A. Horger
Publikováno v:
Psychopharmacology. 142:31-40
The mesolimbic dopamine (DA) system has been implicated in conditioned reward (CR), locomotor sensitization, and the reinforcing properties of psychomotor stimulants. Stimuli with formerly motivationally neutral properties that gain incentive propert
Autor:
Arnon Rosenthal, Mary Hynes, Richard Vandlen, Laura C. Simmons, Eugene M. Johnson, Deniz Kirik, Brian A. Horger, Barbara Moffat, Heidi S. Phillips, Anders Björklund, Li-Chong Wang, Mark Armanini, Merry C. Nishimura, Kristian Todd Poulsen, Carl Rosenblad, Jeffrey Milbrandt
Publikováno v:
The Journal of Neuroscience. 18:4929-4937
Glial cell line-derived neurotrophic factor (GDNF) exhibits potent effects on survival and function of midbrain dopaminergic (DA) neurons in a variety of models. Although other growth factors expressed in the vicinity of developing DA neurons have be
Publikováno v:
Life Sciences. 55:1245-1251
This study assessed the ability of cocaine to increase synaptic levels of dopamine (DA) in the ventral striatum (VS) and medial prefrontal cortex (mPFC) following repeated daily exposure to amphetamine or nicotine. In vivo microdialysis was used to a
Publikováno v:
Brain Research. 543:227-235
The effects of neurotoxic lesions to the medial prefrontal cortex on both the acquisition and maintenance of intravenous cocaine self-administration were examined. In one experiment, acquisition of intravenous cocaine self-administration (0.25, 0.5 o
Autor:
Jack R. Nation, Cathy A. Grover, Juan A. Salinas, C. Kyle Pugh, Rachel Peltier, Brian A. Horger, Gerald D. Bratton
Publikováno v:
Behavioral Neuroscience. 105:998-1003
Publikováno v:
NeuroReport. 2:53-56
The present study examined the effect of pre-exposure to a moderate dose of caffeine (20 mg kg-1) on the acquisition of self-administration of cocaine (0.125 mg kg-1/infusion or 0.25 mg kg-1/infusion) in the rat. Rats pre-exposed to caffeine acquired
Publikováno v:
Alcohol. 7:17-20
Adult male rats were exposed to a standard laboratory diet (N = 20), or an adulterated diet containing 100 ppm added cadmium (N = 20), for 60 days. On Day 61, half the animals from each dietary condition received subcutaneous implants of two 30 mg na
Autor:
Chad J. Messer, Brian A. Horger, Jane R. Taylor, Christiana Iyasere, Eric J. Nestler, Melissa T. Berhow
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 19(10)
The mesolimbic dopamine (DA) system has been implicated in drug reward, locomotor sensitization, and responding for reward-related stimuli [termed conditioned reinforcers (CR)]. Here, we investigated the effect of brain-derived neurotrophic factor (B
Publikováno v:
Brain research. 733(1)
The present study assessed the ability of cocaethylene to induce sensitization to the behavioral activating effects of cocaine in the male Sprague-Dawley rat. Preexposure to cocaethylene (15 or 25 mg/kg) significantly enhanced the locomotor activatin