Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Brian A Keller"'
Autor:
Kaitlyn Grieves, PharmD, Brian C. Keller, MD, PhD, Georgina Waldman, PharmD, BCTXP, Jacqueline E. Clark, PharmD, BCPS, BCTXP
Publikováno v:
JHLT Open, Vol 6, Iss , Pp 100156- (2024)
Background: Mycophenolate mofetil (MMF) is a key immunosuppression agent for lung transplant recipients (LTR); however, the side effects often lead to dose modifications. Kidney transplant literature has shown reductions in MMF dosing led to an incre
Externí odkaz:
https://doaj.org/article/657363c750f644cebfbdd315a391c486
Autor:
Laura Evgin, Carolina S Ilkow, Marie-Claude Bourgeois-Daigneault, Christiano Tanese de Souza, Lawton Stubbert, Michael S Huh, Victoria A Jennings, Monique Marguerie, Sergio A Acuna, Brian A Keller, Charles Lefebvre, Theresa Falls, Fabrice Le Boeuf, Rebecca A Auer, John D Lambris, J Andrea McCart, David F Stojdl, John C Bell
Publikováno v:
Molecular Therapy: Oncolytics, Vol 3, Iss C (2016)
The systemic delivery of therapeutic viruses, such as oncolytic viruses or vaccines, is limited by the generation of neutralizing antibodies. While pseudotyping of rhabdoviruses with the lymphocytic choriomeningitis virus glycoprotein has previously
Externí odkaz:
https://doaj.org/article/03318fbb20d24026bc983751bf71f24d
Publikováno v:
Transplantation Direct, Vol 9, Iss 3, p e1445 (2023)
Background. Community-acquired respiratory viruses (CARVs) are an important cause of morbidity and mortality in lung transplant (LTx) recipients. Despite routine mask-wearing, LTx patients remain at a higher risk of CARV infection than the general po
Externí odkaz:
https://doaj.org/article/62afc4b2439249cc936fd9928e048485
Autor:
Marie-Eve Wedge, Victoria A. Jennings, Mathieu J. F. Crupi, Joanna Poutou, Taylor Jamieson, Adrian Pelin, Giuseppe Pugliese, Christiano Tanese de Souza, Julia Petryk, Brian J. Laight, Meaghan Boileau, Zaid Taha, Nouf Alluqmani, Hayley E. McKay, Larissa Pikor, Sarwat Tahsin Khan, Taha Azad, Reza Rezaei, Bradley Austin, Xiaohong He, David Mansfield, Elaine Rose, Emily E. F. Brown, Natalie Crawford, Almohanad Alkayyal, Abera Surendran, Ragunath Singaravelu, Dominic G. Roy, Gemma Migneco, Benjamin McSweeney, Mary Lynn Cottee, Egon J. Jacobus, Brian A. Keller, Takafumi N. Yamaguchi, Paul C. Boutros, Michele Geoffrion, Katey J. Rayner, Avijit Chatterjee, Rebecca C. Auer, Jean-Simon Diallo, Derrick Gibbings, Benjamin R. tenOever, Alan Melcher, John C. Bell, Carolina S. Ilkow
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
RNA-based viruses can be engineered to express artificial microRNAs (amiRNAs). Here, the authors identify a candidate amiRNA that confers a replicative advantage to oncolytic viruses, enhancing their anticancer potency, and show that intercellular tr
Externí odkaz:
https://doaj.org/article/4c63ee51ae0d403a99532dab542cb349
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0291905 (2023)
Polyethylene glycol-23 glyceryl distearate (GDS-23), a diacylglycerol polyethylene glycol adduct, forms niosomes with a liposome-like structure and functions as an active ingredient in drug delivery systems. In addition, it upregulates antioxidant pr
Externí odkaz:
https://doaj.org/article/1207f987d36a4c60a9a33aebd7370a31
Autor:
Arindam Singha, Pamela K. Burcham, April Logan, Zeinab El Boghdadly, Molly M. Howsare, David R. Nunley, Mark E. Lustberg, Brian C. Keller
Publikováno v:
Transplantology, Vol 2, Iss 2, Pp 129-139 (2021)
Cytomegalovirus (CMV) prophylaxis with valganciclovir is the standard of practice in most transplant centers, but treatment-related leukopenia can limit valganciclovir’s use. Therefore, we evaluated letermovir, a novel antiviral agent recently appr
Externí odkaz:
https://doaj.org/article/7dd09e0fab4d41d79674f857a7a0a8f7
Autor:
Jefferson M. Jones, Ian Kracalik, Meenakshi M. Rana, Ann Nguyen, Brian C. Keller, Aaron Mishkin, Charles Hoopes, Thomas Kaleekal, Abhinav Humar, Juan Vilaro, Gene Im, Lou Smith, April Justice, Collette Leaumont, Stephen Lindstrom, Brett Whitaker, Ricardo M. La Hoz, Marian G. Michaels, David Klassen, Wendi Kuhnert, Sridhar V. Basavaraju
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 2, Pp 552-555 (2021)
We conducted public health investigations of 8 organ transplant recipients who tested positive for severe acute respiratory syndrome coronavirus 2 infection. Findings suggest the most likely source of transmission was community or healthcare exposure
Externí odkaz:
https://doaj.org/article/2544bcf368bb4784b7b34476d18f8155
Autor:
Justin P. Rosenheck, DO, David J. Ross, MD, Mena Botros, MD, Alexander Wong, MD, Jonathan Sternberg, PhD, Yen-An Chen, MS, Nathan Liang, BA, Amy Baer, MS, Ebad Ahmed, PhD, Ryan Swenerton, PhD, Bernhard G. Zimmermann, PhD, Gordon Fehringer, PhD, Zachary P. Demko, PhD, Michael Olymbios, MD, Paul R. Billings, MD, PhD, Brian C. Keller, MD, PhD
Publikováno v:
Transplantation Direct, Vol 8, Iss 4, p e1317 (2022)
Background. Lung transplant patients are vulnerable to various forms of allograft injury, whether from acute rejection (AR) (encompassing acute cellular rejection [ACR] and antibody-mediated rejection [AMR]), chronic lung allograft dysfunction (CLAD)
Externí odkaz:
https://doaj.org/article/9edea27d61424d5caf9b33424f5d3cb2
Publikováno v:
Psychological Methods.
Publikováno v:
Behavior Research Methods. 54:2962-2980
Missing data such as data missing at random (MAR) are unavoidable in real data and have the potential to undermine the validity of research results. Multiple imputation is one of the most widely used MAR-based methods in education and behavioral scie