Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Brian Myhr"'
Autor:
Melvin Lloyd, Jenness B. Majeska, Robert R. Delongchamp, Takashi Omori, Leon F. Stankowski, Sai-Mei Hou, Colin Riach, B. Bhaskar Gollapudi, Peter Jenkinson, Julie Clements, Masamitsu Honma, Shinobu Wakuri, George Bolcsfoldi, Jane Clarke, Freddy Van Goethem, Maria A. Cifone, Brian Burlinson, Isao Yoshimura, Richard H.C. San, Michael D. Fellows, Robert Durward, Michael R. O’Donovan, Martha M. Moore, Ajit K. Thakur, Brian Myhr
Publikováno v:
Environmental and Molecular Mutagenesis. 47:1-5
The Mouse Lymphoma Assay (MLA) Workgroup of the International Workshop on Genotoxicity Testing (IWGT), comprised of experts from Japan, Europe, and the United States, met on August 29, 2003, in Aberdeen, Scotland, United Kingdom. This meeting of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::928879f0d5ade537f6642c80585dfc39
https://doi.org/10.1002/em.20159
https://doi.org/10.1002/em.20159
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 548:1-7
Syrian hamster embryo (SHE) cell transformation has been used for many years to study chemical carcinogenesis in vitro. It has been shown that this assay is probably the most predictive short-term test system for identifying rodent carcinogens. Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f7e67b3553cd1cc93b83b4f3c78879
https://doi.org/10.1016/j.mrfmmm.2003.05.002
https://doi.org/10.1016/j.mrfmmm.2003.05.002
Autor:
Michael R. O’Donovan, George Bolcsfoldi, Martha M. Moore, Robert Preston, Stephan Kirchner, Michael D. Fellows, Paul Kirby, Richard H.C. San, Ajit K. Thakur, Brian Myhr, Takashi Omori, Isao Yoshimura, Wolfgang Muster, Masamitsu Honma, Maria A. Cifone, B. Bhaskar Gollapudi, Peter Jenkinson, Robert R. Delongchamp, Shinobu Wakuri, Julie Clements, Marie-Claude Ouldelhkim, Colin Riach, Jo Oliver, Kamala Pant, Leon F. Stankowski
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 540:127-140
The Mouse Lymphoma Assay (MLA) Workgroup of the International Workshop on Genotoxicity Tests (IWGT) met on June 28th and 29th, 2002, in Plymouth, England. This meeting of the MLA group was devoted to discussing the criteria for assay acceptance and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9fa36bfb90fe6743c29df407360e734
https://doi.org/10.1016/j.mrgentox.2003.07.003
https://doi.org/10.1016/j.mrgentox.2003.07.003
Autor:
Jane Cole, Ann D. Mitchell, Martha M. Moore, George Bolcsfoldi, Karen Harrington-Brock, Marie-Claude Ouldelhkim, B. Bhaskar Gollapudi, Takumi Awogi, Brian Myhr, Julie Clements, Richard H.C. San, Michael R. O’Donovan, Wolfgang Muster, Hiroyasu Shimada, Masamitsu Honma, Leon F. Stankowski
Publikováno v:
Environmental and Molecular Mutagenesis. 35:185-190
The Mouse Lymphoma Assay (MLA) Workgroup addressed and reached consensus on a number of issues. Discussion focused on five areas: (1) acceptable assay versions; (2) cytotoxicity measure; (3) 24-hr treatment; (4) microwell colony counting and sizing;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e25ed013b256a977fb2f9d23759c9636
https://doi.org/10.1002/(sici)1098-2280(2000)35:3<185::aid-em5>3.0.co
https://doi.org/10.1002/(sici)1098-2280(2000)35:3<185::aid-em5>3.0.co
Publikováno v:
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 394:177-303
The L5178Y/tk+/−-3.7.2C mouse lymphoma assay (MLA) which detects mutations affecting the heterozygous thymidine kinase (tk) locus is capable of responding to chemicals acting as clastogens as well as point mutagens. Improvements in the assay to enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c1757e1ed39394552127e28ff2b7a5d
https://doi.org/10.1016/s1383-5718(97)00115-0
https://doi.org/10.1016/s1383-5718(97)00115-0
Autor:
Lutz Müller, Julie Clements, Philip Wilcox, Jane Cole, Marie-Claude Oudelhkim, Masamitsu Homna, T.J. Oberly, Véronique Thybaud, Colette J. Rudd, George Bolcsfoldi, Brian Myhr, Martha M. Moore, Jenness B. Majeska, Hiroyasu Shimada, Donald Clive, Toshio Sofuni
Publikováno v:
Environmental and Molecular Mutagenesis. 25:165-168
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9935bfcbcfd13f9248ac1dddc7a26f04
https://doi.org/10.1002/em.2850250211
https://doi.org/10.1002/em.2850250211
Publikováno v:
Mutation Research Letters. 325:145-148
Transgenic mouse models are being used with increasing frequency for mutational and toxicological studies. One such system. MutaMouse, contains a stably integrated lambda-gt10LacZ shuttle vector in the mouse genome. We describe the use of dual color
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e04dd35c1ee6e761e123ede653841f3
https://doi.org/10.1016/0165-7992(94)90077-9
https://doi.org/10.1016/0165-7992(94)90077-9
Autor:
Owen R. Moss, György A. Csanády, James A. Bond, Leslie Recio, Brian Myhr, Siv M. Osterman-Golkar, Max J. Turner
Publikováno v:
Toxicology and Applied Pharmacology. 117:58-64
1,3-Butadiene (BD) is carcinogenic in the B6C3F1 mouse in multiple organs, including lung and liver. We conducted a study to measure the frequency of BD mutations in mouse tissues using a transgenic mouse (Muta mouse; MM). MM is a BALB c × DBA 2 (CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::399f799d888f0bd64343dad82c7d62bc
https://doi.org/10.1016/0041-008x(92)90217-g
https://doi.org/10.1016/0041-008x(92)90217-g
Autor:
Brian Myhr, Motoi Ishidate, Sheila M. Galloway, John Ashby, David Scott, Richard R. Marshall, David J. Brusick
Publikováno v:
Mutation Research/Reviews in Genetic Toxicology. 257:147-205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::843992711c3cc7aa256ed26004f78801
https://doi.org/10.1016/0165-1110(91)90024-p
https://doi.org/10.1016/0165-1110(91)90024-p
Autor:
Brian Myhr
Publikováno v:
Environmental and Molecular Mutagenesis. 18:308-315
MutaMouse is a transgenic mouse engineered to detect mutations in vivo in any tissue of choice by using simple laboratory methods. The target is a bacterial lacZ gene incorporated via lambda phage into the genome of each mouse cell such that a concat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef89c1374a3a2bece6f9c62d73b271e9
https://doi.org/10.1002/em.2850180420
https://doi.org/10.1002/em.2850180420