Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Brian, Turpin"'
Autor:
Lucas Moreno, Pierre Teira, James M. Croop, Nicolas U. Gerber, Nicolas André, Isabelle Aerts, Luis Gros Subias, Bram De Wilde, Francisco Bautista, Brian Turpin, Srinivasa Kunduri, Ali Hamidi, Tatiana Lawrence, Keri A. Streby
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
BackgroundThe survival rates for pediatric patients with relapsed and refractory tumors are poor. Successful treatment strategies are currently lacking and there remains an unmet need for novel therapies for these patients. We report here the results
Externí odkaz:
https://doaj.org/article/f28a1250c8b1469e8458cf378d213834
Autor:
Jo Cooke-Barber, Joseph G. Brungardt, Michael Sorger, Joseph G. Pressey, Brian Turpin, Rajaram Nagarajan, Sara Szabo, Joel Sorger, Neil Johnson, Roshni Dasgupta
Publikováno v:
Annals of Surgical Oncology. 30:3658-3665
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04b9bf1ea081160cbd4a9e5e320bfabf
https://doi.org/10.1245/s10434-023-13097-z
https://doi.org/10.1245/s10434-023-13097-z
Autor:
Kristin Baird, John Glod, Seth M. Steinberg, Denise Reinke, Joseph G. Pressey, Leo Mascarenhas, Noah Federman, Neyssa Marina, Sant Chawla, Joanne P. Lagmay, John Goldberg, Mohammed Milhem, David M. Loeb, James E. Butrynski, Brian Turpin, Arthur Staddon, Sheri L. Spunt, Robin L. Jones, Eve T. Rodler, Scott M. Schuetze, Scott H. Okuno, Lee Helman
Publikováno v:
Sarcoma, Vol 2020 (2020)
Purpose. Osteosarcoma is a rare cancer and a third of patients who have completed primary treatment will develop osteosarcoma recurrence. The Src pathway has been implicated in the metastatic behavior of osteosarcoma; about 95% of samples examined ex
Externí odkaz:
https://doaj.org/article/167aeada11894cf68e9583bfc2edd879
Publikováno v:
Journal of Pediatric Surgery Case Reports, Vol 29, Iss C, Pp 9-13 (2018)
Malignant pediatric tracheal tumors are rare and often present with non-specific findings. Here we present the first case of a primary Ewing tracheal sarcoma in a pediatric patient. Initial presentation, surgical management, post-operative care, and
Externí odkaz:
https://doaj.org/article/4d248887a8aa45608be16068c2316d48
Autor:
Brigitte C. Widemann, Yao Lu, Denise Reinke, Scott H. Okuno, Christian F. Meyer, Gregory M. Cote, Rashmi Chugh, Mohammed M. Milhem, Angela C. Hirbe, AeRang Kim, Brian Turpin, Joseph G. Pressey, Eva Dombi, Nalini Jayaprakash, Lee J. Helman, Ndidi Onwudiwe, Karen Cichowski, John P. Perentesis
Publikováno v:
Sarcoma, Vol 2019 (2019)
Purpose. There are no known effective medical treatments for refractory MPNST. Inactivation of the NF1 tumor suppressor in MPNST results in upregulation of mTOR (mammalian target of rapamycin) signaling and angiogenesis, which contributes to disease
Externí odkaz:
https://doaj.org/article/401c98540a2a455a8f01beecb09b82fe
Autor:
Joseph S. Palumbo, Brett Monia, Alexey Revenko, David P. Witte, Maureen Shaw, Eric S. Mullins, Eleana Harmel-Laws, Kris A. Steinbrecher, Matthew J. Flick, Keith Kombrinck, Leah Rosenfeldt, Whitney Miller, Brian Turpin
PDF file - 1869KB, Modest ASO-mediated decrease in circulating prothrombin does not significantly affect mucosal injury, inflammatory cell accumulation or local inflammatory cytokine production following DSS challenge (S1). Resolution of inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d04c9fd2aa970a0580c6314a07c8d57
https://doi.org/10.1158/0008-5472.22399734
https://doi.org/10.1158/0008-5472.22399734
Autor:
Donna, Perazzo, Ryan, Moore, Nadine A, Kasparian, Megan, Rodts, Tzipi, Horowitz-Kraus, Lori, Crosby, Brian, Turpin, Andrew F, Beck, John, Hutton
Publikováno v:
Pediatric Research. 92:966-978
Abstract Literacy is a major social determinant of health, rooted in skills that develop during early childhood. Children arriving at kindergarten unprepared to learn to read are more likely to have low reading proficiency thereafter. General and hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6be9c23ba67f2d735a6f4e7853ffafa
https://doi.org/10.1038/s41390-022-01934-y
https://doi.org/10.1038/s41390-022-01934-y
Autor:
Benjamin Mizukawa, Vanessa A Fabrizio, Neerav Shukla, Sharon M. Castellino, Daniel S. Wechsler, Marilyn Winchester, Nancy Bouvier, Ahmet Zehir, Brian Turpin, David S. Shulman, Himalee S. Sabnis, Jason Fangusaro, Julia Glade-Bender, Steven G. DuBois, Chanta Whitlow, Laura Agresta
Publikováno v:
J Clin Oncol
PURPOSE The US Food and Drug Administration–expanded access program (EAP) uses a single patient use (SPU) mechanism to provide patient access to investigational agents in situations where no satisfactory or comparable therapy is available. Genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca0f29b257451d4d334e3337311226c
https://doi.org/10.1200/jco.21.01213
https://doi.org/10.1200/jco.21.01213
Autor:
Tuna Toptan, Marion G Brusadelli, Brian Turpin, David P Witte, Jordi Surrallés, Eunike Velleuer, Martin Schramm, Ralf Dietrich, Ruud H Brakenhoff, Patrick S Moore, Yuan Chang, Susanne I Wells
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209235 (2018)
Fanconi anemia is a rare genome instability disorder with extreme susceptibility to squamous cell carcinoma of the head and neck and anogenital tract. In patients with this inherited disorder, the risk of head and neck cancer is 800-fold higher than
Externí odkaz:
https://doaj.org/article/051fef512a1849bdabf6f17fabc8c014
Autor:
Berkley E. Gryder, Joseph G. Pressey, Vladimir V. Kalinichenko, Johnny Donovan, Athena Pyros, Parvathi Sudha, Sushmitha Vallabh, Douglas P. Millay, Sara Szabo, Samriddhi Shukla, Artem Barski, Brian Turpin, Tanya V. Kalin, Javed Khan, David Milewski, Arun Pradhan, Yan Xu
Publikováno v:
Oncogene
The PAX3-FOXO1 fusion protein is the key oncogenic driver in fusion positive rhabdomyosarcoma (FP-RMS), an aggressive soft tissue malignancy with a particularly poor prognosis. Identifying key downstream targets of PAX3-FOXO1 will provide new therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786b6ffe7846f3f7958f2a15c9922e77
https://doi.org/10.1038/s41388-021-01694-9
https://doi.org/10.1038/s41388-021-01694-9