Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Brian, Orr"'
Autor:
Lixin Zhang, Robert Edwards, Mary Strange, Anda Vlad, Syed Zaidi, Mackenzy Radolec, Brian Orr
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/9f37c6fa53504f269f166165af420744
Autor:
Shalkar Adambekov, Samia Lopa, Robert P. Edwards, Lara Lemon, Shu Wang, Sarah E. Taylor, Brian Orr, Faina Linkov
Publikováno v:
Cancer Medicine, Vol 9, Iss 20, Pp 7388-7397 (2020)
Abstract Background Intraperitoneal/intravenous chemotherapy (IP/IV) was associated with improved survival for ovarian cancer (OC) patients in several randomized clinical trials. However, the uptake of IP/IV in clinical practice is varied due to conf
Externí odkaz:
https://doaj.org/article/b2eda42893b04c659876a32abf46333e
Autor:
Lara S. Lemon, Brian Orr, Francesmary Modugno, Ronald J. Buckanovich, Lan Coffman, Robert P. Edwards, Sarah Taylor
Publikováno v:
Gynecologic Oncology. 165:60-66
Evaluate the association between metformin and survival in women with Type 2 diabetes (T2DM) and breast, endometrial and ovarian cancer- 3 hormonally mediated cancers.We evaluated outcomes in a cohort of 6225 women with T2DM with a new diagnosis of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847f3ab1eac09b13262ce3a290425d29
https://doi.org/10.1016/j.ygyno.2022.01.022
https://doi.org/10.1016/j.ygyno.2022.01.022
Publikováno v:
Environmental Education Research. 28:560-580
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e63d2615a6f9e90c2284e5e0b0dc7b
https://doi.org/10.1080/13504622.2022.2045905
https://doi.org/10.1080/13504622.2022.2045905
Autor:
Pawel Kalinski, Robert P. Edwards, David L. Bartlett, Per H. Basse, Melissa Grimm, Weijian Jiang, Francesmary Modugno, Jamie Voyten, Ravikumar Muthuswamy, Brian Orr, Saumendra N. Sarkar, Saigopalakrishna Yerneni, Marie-Nicole Theodoraki
Interplay between IFNα and COX-2/PGE2 system in the regulation of and suppressive inflammatory mediators.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b561787e5a885a50314b1e9802c24b1
https://doi.org/10.1158/0008-5472.22418853.v1
https://doi.org/10.1158/0008-5472.22418853.v1
Autor:
Pawel Kalinski, Robert P. Edwards, David L. Bartlett, Per H. Basse, Melissa Grimm, Weijian Jiang, Francesmary Modugno, Jamie Voyten, Ravikumar Muthuswamy, Brian Orr, Saumendra N. Sarkar, Saigopalakrishna Yerneni, Marie-Nicole Theodoraki
Presence of cytotoxic CD8+ T cells (CTL) in tumor microenvironments (TME) is critical for the effectiveness of immune therapies and patients' outcome, whereas regulatory T(reg) cells promote cancer progression. Immune adjuvants, including double-stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7214199175b15584b7afe0949d9ff3a9
https://doi.org/10.1158/0008-5472.c.6510240.v1
https://doi.org/10.1158/0008-5472.c.6510240.v1
Autor:
Pawel Kalinski, Robert P. Edwards, David L. Bartlett, Per H. Basse, Melissa Grimm, Weijian Jiang, Francesmary Modugno, Jamie Voyten, Ravikumar Muthuswamy, Brian Orr, Saumendra N. Sarkar, Saigopalakrishna Yerneni, Marie-Nicole Theodoraki
Dose-dependent response to rintatolimod (RINT) and poly-I:C (pIC) in macrophage cultures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab7f3ae3d11d2bb139696a06eb9b8ea9
https://doi.org/10.1158/0008-5472.22418862.v1
https://doi.org/10.1158/0008-5472.22418862.v1
Autor:
Pawel Kalinski, Robert P. Edwards, David L. Bartlett, Per H. Basse, Melissa Grimm, Weijian Jiang, Francesmary Modugno, Jamie Voyten, Ravikumar Muthuswamy, Brian Orr, Saumendra N. Sarkar, Saigopalakrishna Yerneni, Marie-Nicole Theodoraki
IFNα enhances the response to TLR3 triggering by either poly-I:C or rintatolimod, but prostaglandin inhibition is selectively needed to optimize the pattern of inflammation induced by poly-I:C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05e5d611a1dd9d85dc8b74bab0f3a40
https://doi.org/10.1158/0008-5472.22418859
https://doi.org/10.1158/0008-5472.22418859
Autor:
Anda M. Vlad, Pawel Kalinski, Robert P. Edwards, William Gooding, George Tseng, Chaeryon Kang, Esther Elishaev, Alexandra Pusateri, Adria Suarez Mora, Lixin Zhang, Mainpal Rana, Ibrahim Uygun, Mary Strange, Yusi Fang, Haider Mahdi, Brian Orr
Purpose:Increased prevalence of cytotoxic T lymphocytes (CTL) in the tumor microenvironment (TME) predicts positive outcomes in patients with epithelial ovarian cancer (EOC), whereas the regulatory T cells (Treg) predict poor outcomes. Guided by the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1dc48e5d92deea7c53f59862d61d167
https://doi.org/10.1158/1078-0432.c.6532676
https://doi.org/10.1158/1078-0432.c.6532676
Autor:
Pawel Kalinski, Robert P. Edwards, David L. Bartlett, Per H. Basse, Melissa Grimm, Weijian Jiang, Francesmary Modugno, Jamie Voyten, Ravikumar Muthuswamy, Brian Orr, Saumendra N. Sarkar, Saigopalakrishna Yerneni, Marie-Nicole Theodoraki
The model: Molecular separation of pro-inflammatory and suppressive pathways of dsRNA signaling in cancer TME.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5607636853793a7884ca23f4020dbd42
https://doi.org/10.1158/0008-5472.22418850
https://doi.org/10.1158/0008-5472.22418850