Zobrazeno 1 - 10
of 372
pro vyhledávání: '"Brian, Kirby"'
Autor:
Enzo Errichetti, Peter Wolf, Saakshi Khattri, Patricia Gorecki, Megan Miller, Jingzhi Jiang, Chenglong Han, Brian Kirby
Publikováno v:
Acta Dermato-Venereologica, Vol 104 (2024)
Mild psoriasis may be burdensome; if symptoms are inadequately controlled, switching therapy may be warranted. In the Phase 3 NAVIGATE trial, patients with moderate-to-severe plaque psoriasis received ustekinumab for 16 weeks. Patients with inadequat
Externí odkaz:
https://doaj.org/article/c88434ac983840359fa3629d2fa93948
Autor:
David J. Morales-Heil, Li Cao, Cheryl Sweeney, Anna Malara, Frank Brown, Philip Milam, Milan Anadkat, Jessica Kaffenberger, Benjamin Kaffenberger, Peter Nagele, Brian Kirby, Elisha D.O. Roberson
Publikováno v:
HGG Advances, Vol 4, Iss 2, Pp 100187- (2023)
Summary: Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease for which few treatment options are available. While most HS is sporadic, some rare kindred show a high-penetrance, autosomal-dominant inheritance. We wanted to identify r
Externí odkaz:
https://doaj.org/article/798c27572ebe4d31ad252729363447b3
Autor:
Andreea Petrasca, Roisin Hambly, Oonagh Molloy, Sean Kearns, Barry Moran, Conor M Smith, Rosalind Hughes, Margaret O'Donnell, Alexandra Zaborowski, Desmond Winter, Jean M Fletcher, Brian Kirby, Anna Malara
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281688 (2023)
Hidradenitis suppurativa (HS) is a chronic relapsing inflammatory skin disease manifested as painful inflamed lesions including deep-seated nodules, abscesses and sinus tracts. The exact aetiology of HS is unclear. Recent evidence suggests that immun
Externí odkaz:
https://doaj.org/article/62b41f3c883844b0ac2ed03aa321a2d1
Autor:
Helen Rea, Brian Kirby
Publikováno v:
Acta Dermato-Venereologica, Vol 99, Iss 11, Pp 945-952 (2019)
Microdialysis is a minimally invasive technique to study metabolic, biochemical, and pharmacological events in tissue. Factors that influence microdialysate collection include molecular weight cutoff of the membrane, perfusion rate, perfusate viscosi
Externí odkaz:
https://doaj.org/article/1bca7ef6011d47c0af4d03e405afd729
Autor:
Mahendra DC, Ding-Fu Shao, Vincent D.-H. Hou, Arturas Vailionis, P. Quarterman, Ali Habiboglu, M. B. Venuti, Fen Xue, Yen-Lin Huang, Chien-Min Lee, Masashi Miura, Brian Kirby, Chong Bi, Xiang Li, Yong Deng, Shy-Jay Lin, Wilman Tsai, Serena Eley, Wei-Gang Wang, Julie A. Borchers, Evgeny Y. Tsymbal, Shan X. Wang
Publikováno v:
Nature Materials. 22:591-598
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d38ddfaf114ccdc6afc4e1677c519953
https://doi.org/10.1038/s41563-023-01522-3
https://doi.org/10.1038/s41563-023-01522-3
Publikováno v:
Case Reports in Dermatological Medicine, Vol 2020 (2020)
Externí odkaz:
https://doaj.org/article/04c5b749d65d40ca818f6a191aeb525f
Autor:
Amit Garg, Sahil Rawal, Oleg Akilov, Afsaneh Alavi, Christine Ardon, Falk G Bechara, Arnon D Cohen, Steven R Cohen, Steven Daveluy, Véronique del Marmol, Maïa Delage, Solveig Esmann, Shani Fisher, Evangelos J Giamarellos-Bourboulis, Amelia Glowaczewska, Noah Goldfarb, Elena Gonzalez Brant, Øystein Grimstad, Sandra Guilbault, Iltefat Hamzavi, Rosalind Hughes, John R Ingram, Gregor B E Jemec, Qiang Ju, Naomi Kappe, Brian Kirby, Joslyn S Kirby, Michelle A Lowes, Lukasz Matusiak, Stella Micha, Robert G Micheletti, Angela P Miller, Dagfinn Moseng, Haley B Naik, Aude Nassif, Georgios Nikolakis, So Yeon Paek, Jose Carlos Pascual, Errol Prens, Barry Resnik, Hassan Riad, Christopher Sayed, Saxon D Smith, Yssra Soliman, Jacek C Szepietowski, Jerry Tan, Linnea Thorlacius, Thrasyvoulos Tzellos, Hessel H van der Zee, Bente Villumsen, Lanqi Wang, Christos C Zouboulis, Andrew Strunk
Publikováno v:
British Journal of Dermatology. 188:808-810
Patients with hidradenitis suppurativa experience significant life impact related to their disease. Younger age, Black race, high BMI, active smoking, flares, depression, anxiety, high comorbidity burden, disability, and difficult access to a dermato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::460a9d966897825035aeb1015abebdbc
https://doi.org/10.1093/bjd/ljad069
https://doi.org/10.1093/bjd/ljad069
Autor:
Conor M Smith, Roisin Hambly, Solene Gatault, Luis F Iglesias-Martinez, Sean Kearns, Helen Rea, Vivien Marasigan, Kate Lynam-Loane, Shivashini Kirthi, Rosalind Hughes, Jean M Fletcher, Walter Kolch, Brian Kirby
Publikováno v:
British Journal of Dermatology. 188:290-310
Lesional HS skin was analysed using RNA-sequencing to assess the predicted functional interplay between B cells and macrophages. Our findings support the idea that TGF-beta plays a key role in HS pathogenesis. It is likely that the development of tun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b7b062d997af442b56762f8233db54
https://doi.org/10.1093/bjd/ljac048
https://doi.org/10.1093/bjd/ljac048
Autor:
Roisin Hambly, Solene Gatault, Conor M Smith, Luis F Iglesias-Martinez, Sean Kearns, Helen Rea, Vivien Marasigan, Kate Lynam-Loane, Shivashini Kirthi, Rosalind Hughes, Jean M Fletcher, Walter Kolch, Brian Kirby
Publikováno v:
British Journal of Dermatology. 188:52-63
Background Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder with significant morbidity. The pathogenesis remains incompletely understood although immune dysregulation plays an important role. It is challenging to treat and approx
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb8810b5a5465ec4ad8f49f4388140f6
https://doi.org/10.1093/bjd/ljac007
https://doi.org/10.1093/bjd/ljac007
Autor:
Agnes Szentpetery, Eric Heffernan, Martina Gogarty, Lisa Mellerick, Janet McCormack, Muhammad Haroon, Musaab Elmamoun, Phil Gallagher, Genevieve Kelly, Aurelie Fabre, Brian Kirby, Oliver FitzGerald
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-11 (2017)
Abstract Background The aim was to study changes in immunohistochemical expression markers of synovial and skin inflammation, clinical outcomes and magnetic resonance imaging (MRI) scores with abatacept treatment in patients with psoriatic arthritis
Externí odkaz:
https://doaj.org/article/24d946bf0ae744b8bb810a6626c223ce