Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Brian, Fox"'
Autor:
Barry J. Byrne, Giancarlo Parenti, Benedikt Schoser, Ans T. van der Ploeg, Hung Do, Brian Fox, Mitchell Goldman, Franklin K. Johnson, Jia Kang, Nickita Mehta, John Mondick, M. Osman Sheikh, Sheela Sitaraman Das, Steven Tuske, Jon Brudvig, Jill M. Weimer, Tahseen Mozaffar
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
Enzyme replacement therapy (ERT) is the only approved disease-modifying treatment modality for Pompe disease, a rare, inherited metabolic disorder caused by a deficiency in the acid α-glucosidase (GAA) enzyme that catabolizes lysosomal glycogen. Fir
Externí odkaz:
https://doaj.org/article/80f9631db5ec471a9488eaff38c0f152
Autor:
Kristl G. Claeys, Hani Kushlaf, Syed Raza, Noemi Hummel, Simon Shohet, Ian Keyzor, Agnieszka Kopiec, Ryan Graham, Brian Fox, Benedikt Schoser
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background The minimal clinically important difference (MCID) is the smallest change in outcome that physicians or patients would consider meaningful and is relevant when evaluating disease progression or the efficacy of interventions. Studi
Externí odkaz:
https://doaj.org/article/038589708d914771b4227aa70fd5c9b8
Autor:
Carla Casulo, Armando Santoro, Guillaume Cartron, Kiyoshi Ando, Javier Munoz, Steven Le Gouill, Koji Izutsu, Simon Rule, Pieternella Lugtenburg, Jia Ruan, Luca Arcaini, Marie‐Laure Casadebaig, Brian Fox, Nurgul Kilavuz, Nils Rettby, Justine Dell'Aringa, Lilia Taningco, Richard Delarue, Myron Czuczman, Thomas Witzig
Publikováno v:
Cancer Reports, Vol 6, Iss 1, Pp n/a-n/a (2023)
Abstract Background Studies suggest that immune checkpoint inhibitors may represent a promising strategy for boosting immune responses and improving the antitumor activity of standard therapies in patients with relapsed/refractory hematologic maligna
Externí odkaz:
https://doaj.org/article/53982eb6c7094c0dbc546b6a65f550a0
Autor:
Ian Keyzor, Simon Shohet, Jeff Castelli, Sheela Sitaraman, Biliana Veleva-Rotse, Jill M. Weimer, Brian Fox, Tobias Willer, Steve Tuske, Louise Crathorne, Klara J. Belzar
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1227 (2023)
The treatment landscape for lysosomal storage disorders (LSDs) is rapidly evolving. An increase in the number of preclinical and clinical studies in the last decade has demonstrated that pharmacological chaperones are a feasible alternative to enzyme
Externí odkaz:
https://doaj.org/article/77e7ce7c2b764f51880d261188c06a9c
Autor:
Dayle Sampson, Thomas D. Yager, Brian Fox, Laura Shallcross, Leo McHugh, Therese Seldon, Antony Rapisarda, Richard B. Brandon, Krupa Navalkar, Nandi Simpson, Sian Stafford, Eliza Gil, Cristina Venturini, Evi Tsaliki, Jennifer Roe, Benjamin Chain, Mahdad Noursadeghi
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Abstract Background There is an urgent need to develop biomarkers that stratify risk of bacterial infection in order to support antimicrobial stewardship in emergency hospital admissions. Methods We used computational machine learning to derive a rul
Externí odkaz:
https://doaj.org/article/f49351239a2f427ab2056944955526c8
Publikováno v:
EURASIP Journal on Wireless Communications and Networking, Vol 2019, Iss 1, Pp 1-17 (2019)
Abstract This paper describes several aspects of the physical layer and over the air interface of Loon. Loon utilizes stratospheric balloon-based high-altitude platforms (HAPs) that use Long-Term Evolution (LTE) to connect people with standard User E
Externí odkaz:
https://doaj.org/article/df6b5b00e3fd436e97db52b49c74d058
Autor:
Samuel A Danziger, Mark McConnell, Jake Gockley, Mary H Young, Adam Rosenthal, Frank Schmitz, David J Reiss, Phil Farmer, Daisy V Alapat, Amrit Singh, Cody Ashby, Michael Bauer, Yan Ren, Kelsie Smith, Suzana S Couto, Frits van Rhee, Faith Davies, Maurizio Zangari, Nathan Petty, Robert Z Orlowski, Madhav V Dhodapkar, Wilbert B Copeland, Brian Fox, Antje Hoering, Alison Fitch, Katie Newhall, Bart Barlogie, Matthew W B Trotter, Robert M Hershberg, Brian A Walker, Andrew P Dervan, Alexander V Ratushny, Gareth J Morgan
Publikováno v:
PLoS Medicine, Vol 17, Iss 11, p e1003323 (2020)
BackgroundThe tumor microenvironment (TME) is increasingly appreciated as an important determinant of cancer outcome, including in multiple myeloma (MM). However, most myeloma microenvironment studies have been based on bone marrow (BM) aspirates, wh
Externí odkaz:
https://doaj.org/article/48a59d8f2fb64baa9b747522459ffea9
Autor:
Jan Philipp Bewersdorf, Vanessa Hasle, Rory Michael Shallis, Ethan G. Thompson, Daniel Lopes de Menezes, Shelonitda Rose, Isaac W. Boss, Stephanie Halene, Torsten Haferlach, Brian Fox, Amer M. Zeidan
Publikováno v:
Blood. 140:6247-6249
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ede1941e7ebc32a71c8fa9b6868ce109
https://doi.org/10.1182/blood-2022-156460
https://doi.org/10.1182/blood-2022-156460
Autor:
Sara Marie Atkinson, Ute Hoffmann, Alf Hamann, Emil Bach, Niels Banhos Danneskiold-Samsøe, Karsten Kristiansen, Kyle Serikawa, Brian Fox, Kim Kruse, Claus Haase, Søren Skov, Anneline Nansen
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 4, Pp 427-440 (2016)
Rodent models of arthritis have been extensively used in the elucidation of rheumatoid arthritis (RA) pathogenesis and are instrumental in the development of therapeutic strategies. Here we utilise delayed-type hypersensitivity arthritis (DTHA), a mo
Externí odkaz:
https://doaj.org/article/5ed44e8c71e447e2b7d84fa30b0d84ec
Autor:
Dayle Sampson, Thomas D. Yager, Brian Fox, Laura Shallcross, Leo McHugh, Therese Seldon, Antony Rapisarda, Roslyn A. Hendriks, Richard B. Brandon, Krupa Navalkar, Nandi Simpson, Sian Stafford, Eliza Gil, Cristina Venturini, Evi Tsaliki, Jennifer Roe, Benjamin Chain, Mahdad Noursadeghi
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/d740ed64c3ac49a68c827986110142dc