Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Brian, Belmontes"'
Autor:
Qiming Zhang, Siyuan Liu, Yedan Liu, Dev Bhatt, Juan Estrada, Brian Belmontes, Xianwen Ren, Jude Canon, Wenjun Ouyang
Publikováno v:
Advanced Genetics, Vol 3, Iss 4, Pp n/a-n/a (2022)
Abstract Liver metastasis is associated with immunotherapy resistance, although the underlying mechanisms remain incompletely understood. By applying single cell RNA‐sequencing to a concurrent subcutaneous and liver tumor murine model to recapitula
Externí odkaz:
https://doaj.org/article/f1e2283ed7594857ac645ecd89069993
Autor:
Jennie C. Kim, Xian Liu, Karen Fitzgerald, Jason S. Eng, Jessica Orf, Sarah A. O’Brien, Brian Belmontes, Amy-Jo Casbon, Sergey V. Novitskiy, Kristin V. Tarbell, Jason DeVoss, Jackson G. Egen
Publikováno v:
Cancer Immunology, Immunotherapy. 72:1327-1335
Type I interferon-mediated activation of immune cells can facilitate the generation of productive tumor antigen-specific T cell responses in solid tumors. The cGAS/STING DNA sensing pathway is a critical upstream mediator of type I interferon product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0c1085f9aa0140df9bbf9ebb6eac27d
https://doi.org/10.1007/s00262-022-03327-w
https://doi.org/10.1007/s00262-022-03327-w
Autor:
Frank J. Calzone, Robert Radinsky, Richard Kendall, Renato Baserga, Steven Vonderfecht, Min Zhu, Mei Mei Tsai, Joanne Ho, Brian Belmontes, John Lu, Elaina Cajulis, Young-A Chung, Petia Mitchell, Pedro J. Beltran
Pancreatic carcinoma is a leading cause of cancer deaths, and recent clinical trials of a number of oncology therapeutics have not substantially improved clinical outcomes. We have evaluated the therapeutic potential of AMG 479, a fully human monoclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d848837cc9c0c0143eba8b9957be18
https://doi.org/10.1158/1535-7163.c.6532043
https://doi.org/10.1158/1535-7163.c.6532043
Autor:
Gottfried E. Konecny, Dennis J. Slamon, Jingwei Qi, Guorong Yang, Victor E. Velculescu, Steven Vonderfecht, Chi-Ming Li, Brian Belmontes, Gordon Moody, Elaina Cajulis, Young-Ah Chung, Petia Mitchell, Frank J. Calzone, Pedro J. Beltran
PDF file - 47KB, Expression analysis in ovarian cancer cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd1df21110e573befdbd946792780ac
https://doi.org/10.1158/1078-0432.22454783.v1
https://doi.org/10.1158/1078-0432.22454783.v1
Autor:
Teresa L. Burgess, Richard Kendall, Robert Radinsky, Brian Belmontes, Hue Kha, Manory Fernando, Martin A. Broome, Karthik Nagapudi, Adrian L. Smith, Joseph L. Kim, Steven Vonderfecht, Mark J. Rose, Quynh Le, Carol Babij, Pedro J. Beltran, Josette Carnahan
Raf inhibitors are under clinical investigation, specifically in patients with tumor types harboring frequent activating mutations in B-Raf. Here, we show that cell lines and tumors harboring mutant B-Raf were sensitive to a novel series of Raf inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0856e6a8497363b776f8b5446fd65d
https://doi.org/10.1158/1535-7163.c.6531411.v1
https://doi.org/10.1158/1535-7163.c.6531411.v1
Autor:
Teresa L. Burgess, Richard Kendall, Robert Radinsky, Brian Belmontes, Hue Kha, Manory Fernando, Martin A. Broome, Karthik Nagapudi, Adrian L. Smith, Joseph L. Kim, Steven Vonderfecht, Mark J. Rose, Quynh Le, Carol Babij, Pedro J. Beltran, Josette Carnahan
Supplementary Data from Selective and Potent Raf Inhibitors Paradoxically Stimulate Normal Cell Proliferation and Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c9218983b878b17334b0ead6834a74
https://doi.org/10.1158/1535-7163.22484454
https://doi.org/10.1158/1535-7163.22484454
Autor:
Gottfried E. Konecny, Dennis J. Slamon, Jingwei Qi, Guorong Yang, Victor E. Velculescu, Steven Vonderfecht, Chi-Ming Li, Brian Belmontes, Gordon Moody, Elaina Cajulis, Young-Ah Chung, Petia Mitchell, Frank J. Calzone, Pedro J. Beltran
Purpose: Insulin-like growth factor 1 receptor (IGF-IR) has been implicated in the pathogenesis of ovarian cancer. Ganitumab is an investigational, fully human monoclonal antibody against IGF-IR. Here, we explore the therapeutic potential of ganituma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3983470ec59a164f7996c351415866
https://doi.org/10.1158/1078-0432.c.6522836.v1
https://doi.org/10.1158/1078-0432.c.6522836.v1
Autor:
Gottfried E. Konecny, Dennis J. Slamon, Jingwei Qi, Guorong Yang, Victor E. Velculescu, Steven Vonderfecht, Chi-Ming Li, Brian Belmontes, Gordon Moody, Elaina Cajulis, Young-Ah Chung, Petia Mitchell, Frank J. Calzone, Pedro J. Beltran
PDF file - 114KB, Expression of Akt and PTEN in OV-90 and TOV-21G cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc538cb1a92ebb99af5688bbe8bdb33
https://doi.org/10.1158/1078-0432.22454798.v1
https://doi.org/10.1158/1078-0432.22454798.v1
Autor:
Gottfried E. Konecny, Dennis J. Slamon, Jingwei Qi, Guorong Yang, Victor E. Velculescu, Steven Vonderfecht, Chi-Ming Li, Brian Belmontes, Gordon Moody, Elaina Cajulis, Young-Ah Chung, Petia Mitchell, Frank J. Calzone, Pedro J. Beltran
PDF file - 56KB, Inhibition of cell growth by ganitumab.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53032e9a8c0ecd90a64bad7fa9bf41c8
https://doi.org/10.1158/1078-0432.22454786
https://doi.org/10.1158/1078-0432.22454786
Autor:
Gottfried E. Konecny, Dennis J. Slamon, Jingwei Qi, Guorong Yang, Victor E. Velculescu, Steven Vonderfecht, Chi-Ming Li, Brian Belmontes, Gordon Moody, Elaina Cajulis, Young-Ah Chung, Petia Mitchell, Frank J. Calzone, Pedro J. Beltran
PDF file - 46KB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fd1e9ee5f092ec3e037e8ea000d8279
https://doi.org/10.1158/1078-0432.22454795.v1
https://doi.org/10.1158/1078-0432.22454795.v1