Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Brian, Armstrong"'
Autor:
Dan Zhao, Haiqing Li, Isa Mambetsariev, Tamara Mirzapoiazova, Chen Chen, Jeremy Fricke, Deric Wheeler, Leonidas Arvanitis, Raju Pillai, Michelle Afkhami, Bihong T. Chen, Martin Sattler, Loretta Erhunmwunsee, Erminia Massarelli, Prakash Kulkarni, Arya Amini, Brian Armstrong, Ravi Salgia
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract We conducted spatial immune tumor microenvironment (iTME) profiling using formalin-fixed paraffin-embedded (FFPE) samples of 25 KRAS-mutated non-small cell lung cancer (NSCLC) patients treated with immune checkpoint inhibitors (ICIs), includ
Externí odkaz:
https://doaj.org/article/84e066ed9cad48ee852f6917439d4ae5
Publikováno v:
PeerJ, Vol 12, p e17478 (2024)
Bolt’s Farm is the name given to a series of non-hominin bearing fossil sites that have often been suggested to be some of the oldest Pliocene sites in the Cradle of Humankind, South Africa. This article reports the results of the first combined Ur
Externí odkaz:
https://doaj.org/article/24073989a56f47f89c357cfdaa7da329
Autor:
Tamara Mirzapoiazova, Liz Tseng, Bolot Mambetsariev, Haiqing Li, Chih-Hong Lou, Alex Pozhitkov, Sravani Keerthi Ramisetty, Sangkil Nam, Isa Mambetsariev, Brian Armstrong, Jyoti Malhotra, Leonidas Arvanitis, Mohd Wasim Nasser, Surinder K. Batra, Steven T. Rosen, Deric L. Wheeler, Sharad S. Singhal, Prakash Kulkarni, Ravi Salgia
Publikováno v:
iScience, Vol 27, Iss 6, Pp 110132- (2024)
Summary: Although up to 80% small cell lung cancer (SCLC) patients’ response is good for first-line chemotherapy regimen, most patients develop recurrence of the disease within weeks to months. Here, we report cytostatic effect of leflunomide (Lefl
Externí odkaz:
https://doaj.org/article/c1d2afcf8682490aa1a6bb5963b1e1f1
Autor:
Kiran Sriram, Zhijie Qi, Dongqiang Yuan, Naseeb Kaur Malhi, Xuejing Liu, Riccardo Calandrelli, Yingjun Luo, Alonso Tapia, Shengyan Jin, Ji Shi, Martha Salas, Runrui Dang, Brian Armstrong, Saul J Priceman, Ping H Wang, Jiayu Liao, Rama Natarajan, Sheng Zhong, Zhen Bouman Chen
Publikováno v:
eLife, Vol 13 (2024)
Chromatin-associated RNAs (caRNAs) form a relatively poorly recognized layer of the epigenome. The caRNAs reported to date are transcribed from the nuclear genome. Here, leveraging a recently developed assay for detection of caRNAs and their genomic
Externí odkaz:
https://doaj.org/article/323739c0fbfa47fda16f95c298657bec
Autor:
Ameish Govindarajan, Nicholas J. Salgia, Haiqing Li, Daniela V. Castro, Tamara Mirzapoiazova, Brian Armstrong, Dan Zhao, Benjamin D. Mercier, Nazli Dizman, Neal Chawla, Zeynep Zengin, Luis Meza, Nishita Tripathi, Nicolas Sayegh, Alex Chehrazi-Raffle, Abhishek Tripathi, Sumanta K. Pal
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
ObjectiveTo characterize and further compare the immune cell populations of the tumor microenvironment (TME) in both clear cell and papillary renal cell carcinoma (RCC) using heavy metal-labeled antibodies in a multiplexed imaging approach (imaging m
Externí odkaz:
https://doaj.org/article/151b8f04129a483a9b5f27668a5f2782
Autor:
Ayantika Sen, Jeanna Enriquez, Mahil Rao, Marla Glass, Yarl Balachandran, Sharjeel Syed, Clare J. Twist, Kenneth Weinberg, Scott D. Boyd, Daniel Bernstein, Amber W. Trickey, Dita Gratzinger, Brent Tan, Mary Gay Lapasaran, Mark A. Robien, Merideth Brown, Brian Armstrong, Dev Desai, George Mazariegos, Clifford Chin, Thomas M. Fishbein, Robert S. Venick, Akin Tekin, Heiner Zimmermann, Ralf U. Trappe, Ioannis Anagnostopoulos, Carlos O. Esquivel, Olivia M. Martinez, Sheri M. Krams
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Post-transplant lymphoproliferative disorder (PTLD) is a serious complication of solid organ transplantation. Predisposing factors include primary Epstein-Barr virus (EBV) infection, reactivation of EBV in recipient B cells, and decreased T cell immu
Externí odkaz:
https://doaj.org/article/ed499bedc49041f58b9bff0fd05f3920
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 300-303 (2020)
Abstract Lymph nodes are important front‐line defense immune tissues, which also act against inflammatory diseases and cancer. Lymph nodes undergo extensive upheavals within newly formed germinal centers (GCs) when exposed to antigens, the molecula
Externí odkaz:
https://doaj.org/article/c534ea0929494478869d33333636f25c
Autor:
Andy I. R. Herries, Lee J. Arnold, Giovanni Boschian, Alexander F. Blackwood, Coen Wilson, Tom Mallett, Brian Armstrong, Martina Demuro, Fiona Petchey, Matthew Meredith-Williams, Paul Penzo-Kajewski, Matthew V. Caruana
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Amanzi Springs is a series of inactive thermal springs located near Kariega in the Eastern Cape of South Africa. Excavations in the 1960s exposed rare, stratified Acheulian-bearing deposits that were not further investigated over the next 50 years. R
Externí odkaz:
https://doaj.org/article/2815376eb5a8433094c2a8a470be4c0f
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 14, Iss , Pp 131-141 (2019)
Human glioblastoma (GBM) is the most aggressive malignancy of the CNS, with less than 5% survival. Despite great efforts to find effective therapeutics, current options remain very limited. To develop a targeted cancer therapeutic, we selected RNA ap
Externí odkaz:
https://doaj.org/article/2e2b1bdf5e424cc8a8d9c8dab8174e8a
Autor:
Olivia M. Martinez, Sheri M. Krams, Mark A. Robien, Mary G. Lapasaran, Matthew P. Arvedson, Andrea Reitsma, Yarl Balachandran, Aleishia Harris-Arnold, Kenneth Weinberg, Scott D. Boyd, Brian Armstrong, Amber Trickey, Clare J. Twist, Dita Gratzinger, Brent Tan, Merideth Brown, Clifford Chin, Dev M. Desai, Thomas M. Fishbein, George V. Mazariegos, Akin Tekin, Robert S. Venick, Daniel Bernstein, Carlos O. Esquivel
Publikováno v:
American Journal of Transplantation. 23:611-618
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ffefcd194dc3c1b844ba058f738bd4
https://doi.org/10.1016/j.ajt.2023.02.014
https://doi.org/10.1016/j.ajt.2023.02.014