Bench to bedside development of GMP grade Rhenium-188-HEDP, a radiopharmaceutical for targeted treatment of painful bone metastases.

Autor: ter Heine R; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands. Electronic address: rob@terheine.nl., Lange R; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands., Breukels OB; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands., Bloemendal HJ; Department of Internal Medicine, Meander Medical Center, Amersfoort, The Netherlands., Rummenie RG; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands., Wakker AM; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands., de Graaf H; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands., Beekman FJ; Section Radiation, Detection & Medical Imaging, TU Delft & MILabs B.V., Utrecht, The Netherlands., van der Westerlaken MM; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands., Malingré MM; Department of Clinical Pharmacy, Meander Medical Center, Amersfoort, The Netherlands., Wielders JP; Department of Clinical Chemistry, Meander Medical Center, Amersfoort, The Netherlands., van den Berg L; Department of Radiology & Nuclear Medicine, Meander Medical Center, Amersfoort, The Netherlands., Hendrikse NH; Department of Clinical Pharmacology & Pharmacy, VU University Medical Center, Amsterdam, The Netherlands., de Klerk JM; Department of Radiology & Nuclear Medicine, Meander Medical Center, Amersfoort, The Netherlands.

Publikováno v: International journal of pharmaceutics [Int J Pharm] 2014 Apr 25; Vol. 465 (1-2), pp. 317-24. Date of Electronic Publication: 2014 Feb 19.