Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Brett Trounson"'
Autor:
Scott B. Laffoon, James D. Doecke, Anne M. Roberts, Jennifer A. Vance, Benjamin D. Reeves, Kelly K. Pertile, Rebecca L. Rumble, Chris J. Fowler, Brett Trounson, David Ames, Ralph Martins, Ashley I. Bush, Colin L. Masters, Paul A. Grieco, Edward A. Dratz, Blaine R. Roberts
Publikováno v:
Proteome Science, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background The Australian Imaging and Biomarker Lifestyle (AIBL) study of aging is designed to aid the discovery of biomarkers. The current study aimed to discover differentially expressed plasma proteins that could yield a blood-based scree
Externí odkaz:
https://doaj.org/article/b5230de3ca49414eb8a11bef4ca6f19f
Autor:
Marcela Cespedes, Kelly R. Jacobs, Paul Maruff, Alan Rembach, Christopher J. Fowler, Brett Trounson, Kelly K. Pertile, Rebecca L. Rumble, Stephanie R. Rainey-Smithe, Christopher C. Rowe, Victor L. Villemagne, Pierrick Bourgeat, Chai K. Lim, Pratishtha Chatterjee, Ralph N. Martins, Arne Ittner, Colin L. Masters, James D. Doecke, Gilles J. Guillemin, David B. Lovejoy
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105783- (2022)
Increasing evidence suggests that kynurenine pathway (KP) dyshomeostasis may promote disease progression in dementia. Studies in Alzheimer's disease (AD) patients confirm KP dyshomeostasis in plasma and cerebrospinal fluid (CSF) which correlates with
Externí odkaz:
https://doaj.org/article/75df2cb1e7904b2c830ffb9d9588ebf8
Autor:
Yihan Li, Xin Huang, Christopher Fowler, Yen Y. Lim, Simon M. Laws, Noel Faux, James D. Doecke, Brett Trounson, Kelly Pertile, Rebecca Rumble, Vincent Doré, Victor L. Villemagne, Christopher C. Rowe, James S. Wiley, Paul Maruff, Colin L. Masters, Ben J. Gu
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7867 (2022)
Alzheimer’s disease (AD) has shown altered immune responses in the periphery. We studied P2X7 (a proinflammatory receptor and a scavenger receptor) and two integrins, CD11b and CD11c, on the surface of circulating leukocytes and analysed their asso
Externí odkaz:
https://doaj.org/article/8af6721597d74e71aa5875b5ecaf241c
Autor:
Xin Huang, Yihan Li, Christopher Fowler, James D. Doecke, Yen Ying Lim, Candace Drysdale, Vicky Zhang, Keunha Park, Brett Trounson, Kelly Pertile, Rebecca Rumble, John W. Pickering, Robert A. Rissman, Floyd Sarsoza, Sara Abdel‐Latif, Yong Lin, Vincent Doré, Victor Villemagne, Christopher C. Rowe, Jurgen Fripp, Ralph Martins, James S. Wiley, Paul Maruff, Jacobo E. Mintzer, Colin L. Masters, Ben J. Gu
Publikováno v:
Alzheimer's & Dementia. 19:2084-2094
Blood-based diagnostics and prognostics in sporadic Alzheimer's disease (AD) are important for identifying at-risk individuals for therapeutic interventions.In three stages, a total of 34 leukocyte antigens were examined by flow cytometry immunopheno
Leukocyte Surface Biomarkers Implicate Deficits of Innate Immunity in Late‐onset Alzheimer’s Disease
Autor:
Yihan Li, Xin Huang, Christopher Fowler, James D Doecke, Brett Trounson, Kelly Pertile, Rebecca Rumble, Yen Ying Lim, Paul Maruff, Jacobo E. Mintzer, Vincent Dore, Christopher Rowe, Jurgen Fripp, James S Wiley, Colin L. Masters, Ben J Gu
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Ying Xia, Vincent Dore, Victor L. Villemagne, Brendan S. Silbert, Jurgen Fripp, James D. Doecke, Elise J Harrison, Adrian Kamer, Robert Grenfell, Madeline Peretti, Simon McBride, Christopher C. Rowe, Paul Maruff, Lidija Milicic, Kelly K. Pertile, Steven J. Collins, Tania Taddei, Christine Thai, Andrea G. Louey, Michael Weinborn, Richard Head, Pierrick Bourgeat, Colin L. Masters, Olivier Salvado, Sabine Bird, S. Lance Macaulay, Rebecca L. Rumble, Michael Vacher, Simon Gibson, Lucy Lim, Amir Fazlollahi, Samantha C. Burnham, Kathryn A. Ellis, Yen Ying Lim, Regan Tyrrell, Julia Bomke, Michael Woodward, Belinda M. Brown, Joanne Robertson, Brett Trounson, Simon M. Laws, Carolyn Chadunow, Magdalene Soh, Liang Jin, Morgan Radler, Greg Savage, Christopher Fowler, Ralph N. Martins, Samantha L. Gardener, Fiona Lamb, Mark Rodrigues, Lucy Mackintosh, David Ames, Stephanie R. Rainey-Smith, Lis Evered, Alan Rembach, Tenielle Porter, Qiao-Xin Li, Nicola T. Lautenschlager, Shiji Varghese, Ashley I. Bush, Hamid R. Sohrabi, Kevin Taddei
Publikováno v:
Journal of Alzheimer's Disease Reports
Background: The Australian Imaging, Biomarkers and Lifestyle (AIBL) Study commenced in 2006 as a prospective study of 1,112 individuals (768 cognitively normal (CN), 133 with mild cognitive impairment (MCI), and 211 with Alzheimer’s disease dementi
Autor:
Scott B. Laffoon, James D. Doecke, Anne M. Roberts, Jennifer A. Vance, Benjamin D. Reeves, Kelly K. Pertile, Rebecca L. Rumble, Chris J. Fowler, Brett Trounson, David Ames, Ralph Martins, Ashley I. Bush, Colin L. Masters, Paul A. Grieco, Edward A. Dratz, Blaine R. Roberts
Publikováno v:
Proteome Science
Proteome Science, Vol 20, Iss 1, Pp 1-17 (2022)
Proteome Science, Vol 20, Iss 1, Pp 1-17 (2022)
Background The Australian Imaging and Biomarker Lifestyle (AIBL) study of aging is designed to aid the discovery of biomarkers. The current study aimed to discover differentially expressed plasma proteins that could yield a blood-based screening tool
Autor:
David Ames, Jennifer A. Vance, Kelly K. Pertile, Scott Laffoon, Rebecca L. Rumble, Paul A. Grieco, Brett Trounson, James D. Doecke, Ashley I. Bush, Blaine R. Roberts, Christopher Fowler, Ralph N. Martins, Colin L. Masters, Benjamin D. Reeves, Edward A. Dratz, Anne M. Roberts
The Australian Imaging and Biomarker Lifestyle (AIBL) study of aging is designed to aid the discovery of biomarkers. The current study aimed to discover differentially expressed plasma proteins that could yield a blood-based screening tool for Alzhei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e609da53cccde71efabd235b034e649
Autor:
Rebecca L. Rumble, Brendan S. Silbert, Kevin Taddei, Christopher Fowler, Shannon Sarros, Qiao-Xin Li, Stephanie R. Rainey-Smith, David Darby, Victor L. Villemagne, Shiji Varghese, David Ames, James D. Doecke, Simon M. Laws, Colin L. Masters, S. Lance Macaulay, Brett Trounson, Steven J. Collins, Alan Rembach, Lisbeth Evered, Kathryn A. Ellis, Kelly K. Pertile, Ashley I. Bush, Ralph N. Martins, Hugo Vanderstichele
Publikováno v:
Journal of Alzheimer's disease : JAD. 61(1)
BACKGROUND: To enhance the accuracy of clinical diagnosis for Alzheimer's disease (AD), pre-mortem biomarkers have become increasingly important for diagnosis and for participant recruitment in disease-specific treatment trials. Cerebrospinal fluid (
Autor:
Alan Rembach, Christopher Fowler, Keyla Perez, Brett Trounson, Rebecca L. Rumble, Victor L. Villemagne, Noel G. Faux, Kevin J. Barnham, Kelly K. Pertile, Andrew D Watt, Paul O'Donnell, Colin L. Masters, Ching-Seng Ang
Publikováno v:
Journal of Alzheimer's Disease. 44:1131-1143
Biomarkers enabling the preclinical identification of Alzheimer's disease (AD) remain one of the major unmet challenges in the field. The blood cellular fractions offer a viable alternative to current cerebrospinal fluid and neuroimaging modalities.