Výsledky vyhledávání - "Brett P, DerGarabedian"

Distinct fibroblast progenitor subpopulation expedites regenerative mucosal healing by immunomodulation

Autor: Kang I. Ko, Brett P. DerGarabedian, Zhaoxu Chen, Rahul Debnath, Annette Ko, Brittany N. Link, Jonathan M. Korostoff, Dana T. Graves

Publikováno v: The Journal of experimental medicine. 220(3)

Injuries that heal by fibrosis can compromise organ function and increase patient morbidity. The oral mucosal barrier has a high regenerative capacity with minimal scarring, but the cellular mechanisms remain elusive. Here, we identify distinct postn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e5d6fd2cc07b013d1ef7d43459dd59
https://pubmed.ncbi.nlm.nih.gov/36584405

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NF-κB perturbation reveals unique immunomodulatory functions in Prx1

Autor: Kang I, Ko, Jean J, Merlet, Brett P, DerGarabedian, Huang, Zhen, Yoko, Suzuki-Horiuchi, Matthew L, Hedberg, Eileen, Hu, Anh T, Nguyen, Stephen, Prouty, Faizan, Alawi, Matthew C, Walsh, Yongwon, Choi, Sarah E, Millar, Ashley, Cliff, Jonathon, Romero, Michael R, Garvin, John T, Seykora, Daniel, Jacobson, Dana T, Graves

Publikováno v: Sci Transl Med

Skin is composed of diverse cell populations that cooperatively maintain homeostasis. Upregulation of the Nuclear factor-kappa B pathway may lead to the development of chronic inflammatory disorders of the skin, but its role during the early events r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::485b699771581d520d664c6eb9c4c375
https://pubmed.ncbi.nlm.nih.gov/35108061

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NF-κB perturbation reveals unique immunomodulatory functions in Prx1 + fibroblasts that promote development of atopic dermatitis

Autor: Kang I. Ko, Jean J. Merlet, Brett P. DerGarabedian, Huang Zhen, Yoko Suzuki-Horiuchi, Matthew L. Hedberg, Eileen Hu, Anh T. Nguyen, Stephen Prouty, Faizan Alawi, Matthew C. Walsh, Yongwon Choi, Sarah E. Millar, Ashley Cliff, Jonathon Romero, Michael R. Garvin, John T. Seykora, Daniel Jacobson, Dana T. Graves

Publikováno v: Science Translational Medicine. 14

Skin is composed of diverse cell populations that cooperatively maintain homeostasis. Up-regulation of the nuclear factor κB (NF-κB) pathway may lead to the development of chronic inflammatory disorders of the skin, but its role during the early ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8685ccd7bc70e70d4edb49387e0b38c2
https://doi.org/10.1126/scitranslmed.abj0324

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Diabetes-Induced NF-κB Dysregulation in Skeletal Stem Cells Prevents Resolution of Inflammation

Autor: Richard M Kralik, Brett P DerGarabedian, Abby L Syverson, Kang I. Ko, Chider Chen, Dana T. Graves, Jerry Choi

Publikováno v: Diabetes

Type 1 diabetes (T1D) imposes a significant health burden by negatively affecting tissue regeneration during wound healing. The adverse effect of diabetes is attributed to high levels of inflammation, but the cellular mechanisms responsible remain el

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bc8d03f829b50e381f772030492d129
https://doi.org/10.2337/db19-0496

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Impact of Periodonto-pathogenic Microbiota and Sociodemographic Variables on Periodontal Status during Pregnancy and Postpartum Period

Autor: Zhen, Huang, Brett P, DerGarabedian, Lu, He, Yueqin, Sha, Zhibin, Chen, Jun, Kang, Yu, Cai, Ping, Gao

Publikováno v: Oral healthpreventive dentistry. 18(1)

This study examines the difference in the oral microbiome during pregnancy and the postpartum period of a Chinese population, with the focus on P. gingivalis, P. intermedia and P. nigrescens and their shift during pregnancy, in order to understand th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6d94b1b88c6ac3a3026f9a87cd1b407e
https://pubmed.ncbi.nlm.nih.gov/33028053

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