Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Brett NIXON"'
Autor:
Cottrell T Tamessar, Amanda L Anderson, Elizabeth G Bromfield, Natalie A Trigg, Shanmathi Parameswaran, Simone J Stanger, Judith Weidenhofer, Hui-Ming Zhang, Sarah A Robertson, David J Sharkey, Brett Nixon, John E Schjenken
Publikováno v:
Reproduction and Fertility, Vol 5, Iss 3, Pp 1-20 (2024)
Seminal fluid extracellular vesicles (SFEVs) have previously been shown to interact with spermatozoa and influence their fertilisation capacity. Here, we sought to extend these studies by exploring the functional consequences of SFEV interactions wit
Externí odkaz:
https://doaj.org/article/383eea1f4ac24984a6676952ae206d05
Autor:
Jacinta H. Martin, Ilana R. Bernstein, Jess M. Lyons, Ariel R. Brady, Nishani S. Mabotuwana, Simone J. Stanger, Camila Salum De Oliveira, Katerina B. Damyanova, Brett Nixon, Tessa Lord
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Oxygen availability can have profound effects on cell fate decisions and survival, in part by regulating expression of hypoxia-inducible factors (HIFs). In the ovary, HIF expression has been characterised in granulosa cells, however, any req
Externí odkaz:
https://doaj.org/article/5dda65dc8bf448c0add10432000f1a06
Autor:
Leah Calvert, Jacinta H Martin, Amanda L Anderson, Ilana R Bernstein, Nathan D Burke, Geoffry N De Iuliis, Andrew L Eamens, Matthew D Dun, Brett D Turner, Shaun D Roman, Mark P Green, Brett Nixon
Publikováno v:
Reproduction and Fertility, Vol 5, Iss 1, Pp 1-16 (2024)
Poly- and per-fluoroalkyl substances (PFAS) are synthetic environmentally persistent chemicals. Despite the phaseout of specific PFAS, their inherent stability has resulted in ubiquitous and enduring environmental contamination. PFAS bioaccumulation
Externí odkaz:
https://doaj.org/article/9d2ac0b7a3964696ab4f2cb10f831f4f
Autor:
Barbara Fraser, Alex Wilkins, Sara Whiting, Mingtao Liang, Diane Rebourcet, Brett Nixon, Robert John Aitken
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0292198 (2024)
The surgical sterilization of cats and dogs has been used to prevent their unwanted breeding for decades. However, this is an expensive and invasive procedure, and often impractical in wider contexts, for example the control of feral populations. A s
Externí odkaz:
https://doaj.org/article/974d321b8e2142d695d057497791a90c
Autor:
Ilana R. Bernstein, Brett Nixon, Jess M. Lyons, Katerina B. Damyanova, Camila S. De Oliveira, Nishani S. Mabotuwana, Simone J. Stanger, Gerard E. Kaiko, Tan Hui Ying, Jon M. Oatley, Nicole M. Skillen, Alyssa J. Lochrin, Jera L. Peters, Tessa Lord
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108424- (2023)
Summary: In this study we explored the role of hypoxia and the hypoxia-inducible transcription factor EPAS1 in regulating spermatogonial stem cell (SSC) function in the mouse testis. We have demonstrated that SSCs reside in hypoxic microenvironments
Externí odkaz:
https://doaj.org/article/2fa4f90c3ac04a43b6a08638c06119ad
Autor:
Yu-Syuan WEI, Wan-Zhen LIN, Tse-En WANG, Wei-Yun LEE, Sheng-Hsiang LI, Fu-Jung LIN, Brett NIXON, Petra SIPILÄ, Pei-Shiue TSAI
Publikováno v:
The Journal of Reproduction and Development, Vol 68, Iss 3, Pp 198-208 (2022)
Spermatozoa acquire fertilization ability through post-translational modifications. These membrane surface alterations occur in various segments of the epididymis. Quiescin sulfhydryl oxidases, which catalyze thiol-oxidation reactions, are involved i
Externí odkaz:
https://doaj.org/article/2941fb26482a4b9da52682752c9d74da
Autor:
Brett Nixon, John E. Schjenken, Nathan D. Burke, David A. Skerrett-Byrne, Hanah M. Hart, Geoffry N. De Iuliis, Jacinta H. Martin, Tessa Lord, Elizabeth G. Bromfield
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Male infertility is a commonly encountered pathology that is estimated to be a contributory factor in approximately 50% of couples seeking recourse to assisted reproductive technologies. Upon clinical presentation, such males are commonly subjected t
Externí odkaz:
https://doaj.org/article/25e45fc90d49407989ed08241cbbef04
Autor:
David A. Skerrett-Byrne, Brett Nixon, Elizabeth G. Bromfield, James Breen, Natalie A. Trigg, Simone J. Stanger, Ilana R. Bernstein, Amanda L. Anderson, Tessa Lord, R. John Aitken, Shaun D. Roman, Sarah A. Robertson, John E. Schjenken
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-22 (2021)
Abstract Background The seminal vesicles synthesise bioactive factors that support gamete function, modulate the female reproductive tract to promote implantation, and influence developmental programming of offspring phenotype. Despite the significan
Externí odkaz:
https://doaj.org/article/627867058628482e8338e8767450f0aa
Autor:
Natalie A. Trigg, David A. Skerrett-Byrne, Jacinta H. Martin, Geoffry N. De Iuliis, Matthew D. Dun, Shaun D. Roman, Andrew L. Eamens, Brett Nixon
Publikováno v:
Data in Brief, Vol 42, Iss , Pp 108032- (2022)
This article reports the proteomic legacy of in vivo exposure to the xenobiotic, acrylamide, on the epithelial cell population of the proximal segments of the mouse epididymis. Specifically, adult male mice were administered acrylamide (25 mg/kg bw/d
Externí odkaz:
https://doaj.org/article/617b62a60f5d4604bcf836a8e3a423c8
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Spermatogonial stem cell (SSC) function is essential for male fertility, and these cells hold potential therapeutic value spanning from human infertility treatments to wildlife conservation. As in vitro culture is likely to be an integral component o
Externí odkaz:
https://doaj.org/article/aaf24434206a4e13bde53469b5909897