Výsledky vyhledávání - "Brett N. Cain"

Akademický článek

Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane

Autor: Adrián González-López, Daniel S. D. Larsson, Ravi Kiran Koripella, Brett N. Cain, Martin Garcia Chavez, Paul J. Hergenrother, Suparna Sanyal, Maria Selmer

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)

Abstract The antibiotic fusidic acid (FA) is used to treat Staphylococcus aureus infections. It inhibits protein synthesis by binding to elongation factor G (EF-G) and preventing its release from the ribosome after translocation. While FA, due to per

Externí odkaz: https://doaj.org/article/688e7a88add545d890d90508e053347f

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Akademický článek

Using permeation guidelines to design new antibiotics—A PASsagE into Pseudomonas aeruginosa

Autor: Brett N. Cain, Paul J. Hergenrother

Publikováno v: Clinical and Translational Medicine, Vol 14, Iss 3, Pp n/a-n/a (2024)

Externí odkaz: https://doaj.org/article/7cd0bab23ae44f5691a1b6987002c689

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An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections

Publikováno v: ACS Central Science. 8:1145-1158

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4adde94bed6860a67d6f9ddf73adce83
https://doi.org/10.1021/acscentsci.2c00598

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Correction to 'An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections'

Publikováno v: ACS Central Science. 8:1362-1362

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::43d1a39f63b9524f0a8fb2ebb1ec1293
https://doi.org/10.1021/acscentsci.2c00969

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