Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Brett Moreau"'
Autor:
Mayuresh M. Abhyankar, Barbara J. Mann, Jeffrey M. Sturek, Savannah Brovero, G. Brett Moreau, Anjali Sengar, Crystal M. Richardson, Sayeh Agah, Anna Pomés, Peter M. Kasson, Mark A. Tomai, Christopher B. Fox, William A. Petri
Publikováno v:
npj Vaccines, Vol 6, Iss 1, Pp 1-6 (2021)
Abstract We developed a SARS-CoV-2 spike subunit vaccine formulation containing dual TLR ligand liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and completely protected mice from a lethal challenge. Two immunizations pr
Externí odkaz:
https://doaj.org/article/da4da1c7c88a4956b31769225afbc2c2
Autor:
Alexandra N. Donlan, Tara E. Sutherland, Chelsea Marie, Saskia Preissner, Benjamin T. Bradley, Rebecca M. Carpenter, Jeffrey M. Sturek, Jennie Z. Ma, G. Brett Moreau, Jeffrey R. Donowitz, Gregory A. Buck, Myrna G. Serrano, Stacey L. Burgess, Mayuresh M. Abhyankar, Cameron Mura, Philip E. Bourne, Robert Preissner, Mary K. Young, Genevieve R. Lyons, Johanna J. Loomba, Sarah J. Ratcliffe, Melinda D. Poulter, Amy J. Mathers, Anthony J. Day, Barbara J. Mann, Judith E. Allen, William A. Petri Jr.
Publikováno v:
JCI Insight, Vol 6, Iss 15 (2021)
Immune dysregulation is characteristic of the more severe stages of SARS-CoV-2 infection. Understanding the mechanisms by which the immune system contributes to COVID-19 severity may open new avenues to treatment. Here, we report that elevated IL-13
Externí odkaz:
https://doaj.org/article/a6c6e0e467c54cfc87c0eba3f4b21036
Autor:
G. Brett Moreau, Girija Ramakrishnan, Heather L. Cook, Todd E. Fox, Uma Nayak, Jennie Z. Ma, E. Ross Colgate, Beth D. Kirkpatrick, Rashidul Haque, William A. Petri, Jr
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 597-606 (2019)
Background: Undernutrition is a serious global problem that contributes to increased child morbidity and mortality, impaired neurocognitive development, and decreased educational and economic attainment. Current interventions are only marginally effe
Externí odkaz:
https://doaj.org/article/6f5457841cc543b9add3f7033bc871f5
Autor:
Sayo E. McCowin, G. Brett Moreau, Rashidul Haque, Janelle A. Noble, Shana L. McDevitt, Jeffrey R. Donowitz, Md Masud Alam, Beth D. Kirkpatrick, William A. Petri, Chelsea Marie
Publikováno v:
EBioMedicine, Vol 67, Iss , Pp 103346- (2021)
Background: genetic susceptibility to infection is mediated by numerous host factors, including the highly diverse, classical human leukocyte antigen (HLA) genes, which are critical genetic determinants of immunity. We systematically evaluated the ef
Externí odkaz:
https://doaj.org/article/4983c00f9b184e1a93aa0066305af214
Publikováno v:
In Molecular Medical Microbiology Edition: Third Edition. 2024:1887-1904
Autor:
Andrea R. Merchak, Samuel Wachamo, Lucille C. Brown, Alisha Thakur, Brett Moreau, Ryan M. Brown, Courtney Rivet-Noor, Tula Raghavan, Alban Gaultier
Publikováno v:
bioRxiv
The gut microbiome consists of the trillions of bacteria, fungi, and viruses that inhabit the digestive tract. These communities are sensitive to disruption from environmental exposures ranging from diet changes to illness. Disruption of the communit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e47eabbd9c16798b5153ff4d6b06e8
https://europepmc.org/articles/PMC10197651/
https://europepmc.org/articles/PMC10197651/
Publikováno v:
Annals of Allergy, Asthma & Immunology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce7c8dcca52e60c46276b2d9930a72be
https://doi.org/10.1016/j.anai.2023.03.009
https://doi.org/10.1016/j.anai.2023.03.009
Autor:
Courtney Rivet-Noor, Andrea R Merchak, Caroline Render, Rebecca M. Beiter, Ryan Brown, Erica Slogar, Austin Keeler, G. Brett Moreau, Sihan Li, Deniz E. Olgun, Tobey Mihn Huu Phan, Jung-Bum Shin, Chris Deppmann, Alban Gaultier
Depression is a common mental health condition with a large social and economic impact. While depression etiology is multifactorial, chronic stress is a well-accepted contributor to disease onset. In addition, depression is associated with altered gu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c67d79d019f30214094cc579b32262c
https://doi.org/10.1101/2022.10.13.512135
https://doi.org/10.1101/2022.10.13.512135
Autor:
Gregory Brett Moreau, Alexandra N. Donlan, William A. Petri, Barbara J. Mann, Jeffrey M. Sturek, Stacey L. Burgess
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 103:1215-1219
Murine models of SARS-CoV-2 infection are critical for elucidating the biological pathways underlying COVID-19. Because human angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV-2, mice expressing the human ACE2 gene have shown promis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0687fbe6aae385078ca59addae24b2bd
https://doi.org/10.4269/ajtmh.20-0762
https://doi.org/10.4269/ajtmh.20-0762
Autor:
Beth D. Kirkpatrick, Stephanie A. Archer-Hartmann, Rashidul Haque, William A. Petri, G. Brett Moreau, Girija Ramakrishnan, Parastoo Azadi, Sara Porfírio
Publikováno v:
Glycobiology
Human breast milk is an incredibly rich and complex biofluid composed of proteins, lipids and complex carbohydrates, including a diverse repertoire of free human milk oligosaccharides (HMOs). Strikingly, HMOs are not digested by the infant but functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12d48c555f7dd8db993bce9643af09a
https://doi.org/10.1093/glycob/cwaa028
https://doi.org/10.1093/glycob/cwaa028