Zobrazeno 1 - 10
of 181
pro vyhledávání: '"Brett M Collins"'
Autor:
Boris Simonetti, Qian Guo, Manuel Giménez-Andrés, Kai-En Chen, Edmund R R Moody, Ashley J Evans, Mintu Chandra, Chris M Danson, Tom A Williams, Brett M Collins, Peter J Cullen
Publikováno v:
PLoS Biology, Vol 20, Iss 4, p e3001601 (2022)
Coat complexes coordinate cargo recognition through cargo adaptors with biogenesis of transport carriers during integral membrane protein trafficking. Here, we combine biochemical, structural, and cellular analyses to establish the mechanistic basis
Externí odkaz:
https://doaj.org/article/844881cd71af4ba98857830ac0cd310b
Autor:
Kirsty J McMillan, Paul J Banks, Francesca LN Hellel, Ruth E Carmichael, Thomas Clairfeuille, Ashley J Evans, Kate J Heesom, Philip Lewis, Brett M Collins, Zafar I Bashir, Jeremy M Henley, Kevin A Wilkinson, Peter J Cullen
Publikováno v:
eLife, Vol 10 (2021)
The endosome-associated cargo adaptor sorting nexin-27 (SNX27) is linked to various neuropathologies through sorting of integral proteins to the synaptic surface, most notably AMPA receptors. To provide a broader view of SNX27-associated pathologies,
Externí odkaz:
https://doaj.org/article/37f2888d4612454586ef6c3bee532043
Autor:
Aashutosh Tripathi, Megha Jain, Mintu Chandra, Sameena Parveen, Rupali Yadav, Brett M Collins, Sankar Maiti, Sunando Datta
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008489 (2020)
Remodelling of the actin cytoskeleton in response to external stimuli is obligatory for many cellular processes in the amoebic cell. A rapid and local rearrangement of the actin cytoskeleton is required for the development of the cellular protrusions
Externí odkaz:
https://doaj.org/article/37e052b5786e4b389599f3852aec6f55
Autor:
Michael D Healy, Manuela K Hospenthal, Ryan J Hall, Mintu Chandra, Molly Chilton, Vikas Tillu, Kai-En Chen, Dion J Celligoi, Fiona J McDonald, Peter J Cullen, J Shaun Lott, Brett M Collins, Rajesh Ghai
Publikováno v:
eLife, Vol 7 (2018)
The COMMD proteins are a conserved family of proteins with central roles in intracellular membrane trafficking and transcription. They form oligomeric complexes with each other and act as components of a larger assembly called the CCC complex, which
Externí odkaz:
https://doaj.org/article/52ef44e3fdd642e78e446da5ae0c2ac6
Autor:
Blessy Paul, Hyun Sung Kim, Markus C Kerr, Wilhelmina M Huston, Rohan D Teasdale, Brett M Collins
Publikováno v:
eLife, Vol 6 (2017)
During infection chlamydial pathogens form an intracellular membrane-bound replicative niche termed the inclusion, which is enriched with bacterial transmembrane proteins called Incs. Incs bind and manipulate host cell proteins to promote inclusion e
Externí odkaz:
https://doaj.org/article/3dc635016835437293196d954486dd77
Autor:
Michelle P Christie, Shu-Hong Hu, Andrew E Whitten, Asma Rehman, Russell J Jarrott, Gordon J King, Brett M Collins, Jennifer L Martin
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0187302 (2017)
The efficient delivery of cellular cargo relies on the fusion of cargo-carrying vesicles with the correct membrane at the correct time. These spatiotemporal fusion events occur when SNARE proteins on the vesicle interact with cognate SNARE proteins o
Externí odkaz:
https://doaj.org/article/e1d5bce38ddc4d1b98de692d745175e8
Autor:
Asma Rehman, Shu-Hong Hu, Zakir Tnimov, Andrew E Whitten, Gordon J King, Russell J Jarrott, Suzanne J Norwood, Kirill Alexandrov, Brett M Collins, Michelle P Christie, Jennifer L Martin
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183366 (2017)
Vesicular transport of cellular cargo requires targeted membrane fusion and formation of a SNARE protein complex that draws the two apposing fusing membranes together. Insulin-regulated delivery and fusion of glucose transporter-4 storage vesicles at
Externí odkaz:
https://doaj.org/article/b085b7d07209489292faba0427e15430
Autor:
Rebeka Butkovič, Alexander P. Walker, Michael D. Healy, Kerrie E. McNally, Meihan Liu, Tineke Veenendaal, Kohji Kato, Nalan Liv, Judith Klumperman, Brett M. Collins, Peter J. Cullen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Commander is a multiprotein complex that orchestrates endosomal recycling of integral cargo proteins and is essential for normal development. While the structure of this complex has recently been described, how cargo proteins are selected fo
Externí odkaz:
https://doaj.org/article/85deafa608c9468da12e9b3d0fe09ce1
Autor:
Yann Gambin, Nicholas Ariotti, Kerrie-Ann McMahon, Michele Bastiani, Emma Sierecki, Oleksiy Kovtun, Mark E Polinkovsky, Astrid Magenau, WooRam Jung, Satomi Okano, Yong Zhou, Natalya Leneva, Sergey Mureev, Wayne Johnston, Katharina Gaus, John F Hancock, Brett M Collins, Kirill Alexandrov, Robert G Parton
Publikováno v:
eLife, Vol 3 (2014)
In mammalian cells three closely related cavin proteins cooperate with the scaffolding protein caveolin to form membrane invaginations known as caveolae. Here we have developed a novel single-molecule fluorescence approach to directly observe interac
Externí odkaz:
https://doaj.org/article/3222892030ff4bd78593681b9cee2d10
Autor:
Asma Rehman, Russell J Jarrott, Andrew E Whitten, Gordon J King, Shu-Hong Hu, Michelle P Christie, Brett M Collins, Jennifer L Martin
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83499 (2013)
Vesicle fusion is an indispensable cellular process required for eukaryotic cargo delivery. The Sec/Munc18 protein Munc18c is essential for insulin-regulated trafficking of glucose transporter4 (GLUT4) vesicles to the cell surface in muscle and adipo
Externí odkaz:
https://doaj.org/article/1f122e2f27a84a0b9f9201719cfb7460