Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Brett Harman"'
Autor:
Daniel Zewge, Xiaoyi Gong, Yizhou Liu, Zhu Liu, Brett Harman, Xiaodong Bu, Huaming Sheng, Mikhail Reibarkh
Publikováno v:
Reaction Chemistry & Engineering. 3:146-150
A hemiaminal derivative identified during preparation of the penultimate of ceftolozane 1, mandated a thorough investigation of the source of the impurity. N,N-Dimethylacetamide (DMAc) subjected to oxidation was found to be the culprit generating oxi