Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Brett H. Pogostin"'
Autor:
Brett H. Pogostin, Kevin J. McHugh
Publikováno v:
Bioengineering, Vol 8, Iss 11, p 155 (2021)
Future infectious disease outbreaks are inevitable; therefore, it is critical that we maximize our readiness for these events by preparing effective public health policies and healthcare innovations. Although we do not know the nature of future patho
Externí odkaz:
https://doaj.org/article/88eece1186a845368375618a50e7e78f
Publikováno v:
Molecules, Vol 24, Iss 3, p 405 (2019)
Determining the pKa of key functional groups is critical to understanding the pH-dependent behavior of biological proteins and peptide-based biomaterials. Traditionally, 1H NMR spectroscopy has been used to determine the pKa of amino acids; however,
Externí odkaz:
https://doaj.org/article/ad1dd3a684c74c9e9b95394d51c2881e
Publikováno v:
Nature Reviews Drug Discovery. 22:387-409
Autor:
Brett H. Pogostin, Gabriel Saenz, Carson C. Cole, Erin M. Euliano, Jeffrey D. Hartgerink, Kevin J. McHugh
Publikováno v:
Bioconjugate Chemistry. 34:193-203
Recently, there has been increased interest in using mannan as an immunomodulatory bioconjugate. Despite notable immunological and functional differences between the reduced (R-Man) and oxidized (O-Man) forms of mannan, little is known about the impa
Autor:
Kathryn R. Brink, Maxwell G. Hunt, Andrew M. Mu, Ken Groszman, Ky V. Hoang, Kevin P. Lorch, Brett H. Pogostin, John S. Gunn, Jeffrey J. Tabor
Publikováno v:
Nature Chemical Biology. 19:451-459
Autor:
Tyler P. Graf, Sherry Yue Qiu, Dhruv Varshney, Mei‐Li Laracuente, Erin M. Euliano, Pujita Munnangi, Brett H. Pogostin, Tsvetelina Baryakova, Arnav Garyali, Kevin J. McHugh
Publikováno v:
Advanced Materials.
Autor:
Brett H. Pogostin, Marina H. Yu, Alon R. Azares, Erin M. Euliano, Cheuk Sun Edwin Lai, Gabriel Saenz, Samuel X. Wu, Adam C. Farsheed, Sarah M. Melhorn, Tyler P. Graf, Darren G. Woodside, Jeffrey D. Hartgerink, Kevin J. McHugh
Publikováno v:
Biomaterials Science. 10:6217-6229
Adjuvants play a critical role in enhancing vaccine efficacy; however, there is a need to develop new immunomodulatory compounds to address emerging pathogens and to expand the use of immunotherapies. Multidomain peptides (MDPs) are materials compose
Publikováno v:
Advanced materials (Deerfield Beach, Fla.).
3D printing has become one of the primary fabrication strategies used in biomedical research. Recent efforts have focused on the 3D printing of hydrogels to create structures that better replicate the mechanical properties of biological tissues. Thes
Autor:
Kevin J. McHugh, Brett H Pogostin
Publikováno v:
Bioengineering
Bioengineering, Vol 8, Iss 155, p 155 (2021)
Bioengineering, Vol 8, Iss 155, p 155 (2021)
Future infectious disease outbreaks are inevitable; therefore, it is critical that we maximize our readiness for these events by preparing effective public health policies and healthcare innovations. Although we do not know the nature of future patho
Autor:
Kathryn R, Brink, Maxwell G, Hunt, Andrew M, Mu, Ken, Groszman, Ky V, Hoang, Kevin P, Lorch, Brett H, Pogostin, John S, Gunn, Jeffrey J, Tabor
Publikováno v:
Nature chemical biology.
Bacteria use two-component system (TCS) signaling pathways to sense and respond to peptides involved in host defense, quorum sensing and inter-bacterial warfare. However, little is known about the broad peptide-sensing capabilities of TCSs. In this s